Publications (484)
ARTICLE
Oligosaccharides in colostrum of Italian and Burkinabe women
Maria Musumeci, Jacques Simpore, Alfonsina D'Agata, Stefano Sotgiu, Salvatore Musumeci
Human milk contains a large number of compounds to provide nutrition and defense for the newborn. Among these, oligosaccharides are present in concentrations up to 12 g/L, and their composition varies during lactation. Colostrum from 53 Burkinabe women were collected at the maternity department of St Camille Medical Centre in Ouagadougou (Burk(...)
Colostrum, Oligosaccharides, Burkinabe women, Italian women, Lactation, Human milk composition, 2-fucosyllactose
ARTICLE
Synchronic macrophage response and Plasmodium falciparum malaria
Maria Musumecia , Jacques Simporeb , Rita Baronec , Andrea Angiusd & Salvatore Musumeci
aDepartment of Biomedical Sciences, University of Catania; bCentre Medical Saint Camille, Ouagadougou and UFR/SVT
Université de Ouagadougou, Burkina Faso; c
Institute of Chemistry and Technology of Polymers – National Research Council
(CNR) – Catania, dInstitute of Population Genetics, CNR, Alghero, eDepartment of Pharmacology, Gynecology/O(...)
Macrophage – Plasmodium falciparum – severe malaria – uncomplicated malaria
ARTICLE
Methylenetetrahydrofolate Reductase (MTHFR) from Mediterranean to Sub-Saharan Areas
Rosa Chillemi, Andrea Angius, Ivana Persico, Alessandro Sassu, Dionigio A. Prodi, Salvatore Musumeci
There are differences in the allele frequency of MTHFR polymorphism between Western and African population. The aim of this study is to determinate the prevalence of MTHFR C677T and A1298C polymorphisms in young and old people living in different areas from Mediterranean to sub-Saharan areas. The observed vs expected genotype frequencies of 67(...)
MTHFR, Sardinia, Sicily, Burkina Faso, young people, old people, nutrition, folic acid, malaria
ARTICLE
Network of sexual contacts and sexually transmitted HIV infection in Burkina Faso
Vito Latora, André Nyamba, Jacques Simpore, Bahiré Sylvette, Sandwidi Diane, Bukiki Sylvére, Salvatore Musumeci
Two thirds of the people who have been infected by human immunodeficiency virus (HIV) in the world live in Sub-Saharan African countries. The results of a study measuring the degree distribution of the network of sexual contacts in Burkina Faso are described. Such a network is responsible for the spread of sexually transmitted diseases, and in(...)
HIV, sexual contacts network, sexually transmitted infections, Burkina Faso, scale-free networks, epidemiology
ARTICLE
Toxoplasma gondii, HCV, and HBV seroprevalence and co‐infection among HIV‐positive and‐negative pregnant women in Burkina Faso
Jacques Simpore, Aly Savadogo, Denise Ilboudo, Marie Christelle Nadambega, Maria Esposito, Justine Yara, Salvatore Pignatelli, Virginio Pietra, Salvatore Musumeci
Toxoplasma gondii (T. gondii) infections can cause serious complications in HIV‐infected pregnant women, leading to miscarriage, stillbirth, birth defects (eg, mental retardation, blindness, epilepsy etc.) and could favor or enhance the mother‐to‐child transmission of HCV, HBV, and HIV vertical transmission. From May 20, 2004 to August 3, 2005(...)
Toxoplasma gondii, HCV, HBV, HIV, pregnant women, Burkina Faso
ARTICLE
[Prevalence of Hepatitis C virus infection in pregnant women and mother-child transmission in Ouagadougou, Burkina Faso]
A K Serme, P D Ilboudo, A Samandoulgou, J Simpore, A Bougouma, A R Sombie
The aim of our study was to estimate the prevalence of Hepatitis C virus (HCV) among pregnant women and the rate of mother-child transmission. Over one month (April 26 to May 25, 2002) blood samples of 200 pregnant women who gave birth at the maternity of the university hospital and Gounguin center medical of Ouagadougou were tested for anti-H(...)
Hépatite C, prévalence, femmes enceintes, transmission mère-enfant, Burkina Faso
ARTICLE
Reduction of mother-to-child transmission of HIV at Saint Camille Medical Centre in Burkina Faso
J Simpore, V Pietra, A Savadogo, S Pignatelli, J B Nikiema, W M C Nadembega, J Yara, N Zoungrana, D Bakouan, V Colizzi, F Castelli, S Musumeci
One thousand three hundred and twenty-eight pregnant women with less than 32 weeks of amenorrhea received voluntary counseling and testing at Saint Camille Medical Center from May 1, 2002 to December 30, 2004. Following informed consent and pre-test counseling, HIV screening was performed in 1,202 women. According to the prevention protocol, H(...)
Mother-to-child transmission, HIV, Nevirapine, RT-PCR, breastfeeding, artificial feeding, Burkina Faso
ARTICLE
Nutrition rehabilitation of undernourished children utilizing Spiruline and Misola
Jacques Simpore, Fatoumata Kabore, Frederic Zongo, Deleli Dansou, Augustin Bere, Salvatore Pignatelli, Daniela M Biondi, Giuseppe Ruberto, Salvatore Musumeci
Malnutrition constitutes a public health problem throughout the world and particularly in developing countries. The objective of the study is to assess the impact of an elementary integrator composed of Spiruline (Spirulina platensis) and Misola (millet, soja, peanut) produced at the Centre Medical St Camille (CMSC) of Ouagadougou, Burkina Fas(...)
Nutrition, undernourished children, Spiruline, Misola, Burkina Faso
ARTICLE
Chitotriosidase activity in colostrum from African and Caucasian women
Maria Musumeci, Lucia Malaguarnera, Jacques Simpore, Rita Barone, Michael Whalen, Salvatore Musumeci
hitotriosidase (ChT), a protein produced by activated macrophages, belongs to the chitinases, a group of enzymes able to hydrolyze chitin, a structural component of fungi and nematodes. A codominant inherited deficiency in ChT activity is frequently reported in plasma of Caucasian subjects, whereas in the African population this deficiency is(...)
Chitotriosidase, colostrum, macrophages, femmes africaines, femmes caucasiennes, activité enzymatique, immunité néonatale, génétique
ARTICLE
Elevated levels of plasma homocysteine in postmenopausal women in Burkina Faso
Rosa Chillemi, Jacques Simpore, Silvia Persichilli, Angelo Minucci, Alfonsina D'Agata, Salvatore Musumeci
Background: Low levels of plasma homocysteine have been found in children and adult populations living in Burkina Faso in association with a low prevalence of coronary heart disease.
Methods: Based on this finding, the levels of plasma homocysteine and other thiols (cysteine, cysteinylglycine, glutathione) in postmenopausal women living in(...)
Plasma homocysteine, postmenopausal women, Burkina Faso, thiol levels, aging, cysteine, glutathione, cysteinylglycine
ARTICLE
Nutrition rehabilitation of HIV-infected and HIV-negative undernourished children utilizing spirulina
Simpore J, Zongo F, Kabore F, Dansou D, Bere A, Nikiema JB, Pignatelli S, Biondi DM, Ruberto G, Musumeci S.
The objective of this study was to assess the impact of an alimentary integrator composed of spirulina (Spirulina platensis; SP), produced at the Centre Médical St Camille of Ouagadougou, Burkina Faso, on the nutritional status of undernourished HIV-infected and HIV-negative children. We compared two groups of children: 84 were HIV-infected an(...)
Malnutrition, Rehabilitation, Spirulina (Spirulina platensis), HIV-infected children, HIV-negative children, Burkina Faso
ARTICLE
Prevalence of blaSHV genes in clinical isolates of Klebsiella pneumoniae at Saint Camille medical Center in Ouagadougou. Isolation of blaSHV11-like gene
Boukaré Zeba, Pere Jacques Simporé, Odile G. Nacoulma, Jean-Marie Frère
Five bacterial strains (4 Klebsiella pneumoniae and 1 Escherichia coli) representative of pathogenic species and resistant to b-lactam antibiotics are investigated to isolate the genes responsible of b-lactamase activity. The use of engineering techniques enables us to show the widespread of blaSHV genes particularly in clinical isolates of K.(...)
b-Lactamases, Klebsiella pneumoniae, blaSHV gene, Saint Camille medical centre, Ouagadougou
ARTICLE
Identification of metallo-b-lactamase from a clinical isolate at Saint Camillle Hospital Center of Ouagadougou/ Burkina Faso
Boukaré Zeba, Pere Jacques Simporé, Odile G. Nacoulma, Jean-Marie Frère
A metallo-b-lactamase was identified from a clinical sample. The host bacteria was identified to be Chryseobacterium Indologenes. This preliminary characterization of the enzyme is reported here.
b-lactamase, metallo-b-lactamase, Chryseobacterium indologenes, Ouagadougou
ARTICLE
Biologic substances present in human colostrums demonstrate the evolution of this essential nutrient for growth and development: Insulin-like growth factor-I and prolactin
Maria Musumeci, Jacques Simporè, Alfonsina D'Agata, Lucia Malaguarnera, Cinzia Carrozza, Cecelia Zuppi, Salvatore Musumeci
The aim of the present study was to see whether the level of both insulin-like growth factor-I (IGF-I) and prolactin (PRL) present in the colostrums of women coming from fairly different environmental conditions showed any significant difference. To this end, the IGF-I and PRL levels of African and Italian women still living in their countries(...)
Nutrition, Santé, Recherche clinique, Afrique, Biologie moléculaire
ARTICLE
HCV and HIV co-infection in pregnant women attending St. Camille Medical Centre in Ouagadougou (Burkina Faso)
J Simpore, D Ilboudo, A Samandoulougou, P Guardo, P Castronovo, Salvatore Musumeci
Five hundred and forty-seven pregnant women with less than 32 weeks of amenorrhoea, attending an antenatal clinic of St. Camille Medical Centre (SCMC) of Ouagadougou were enrolled for a hepatitis C virus (HCV) and HIV co-infection study. Fifty-eight (10.6%) were HIV positive and 18 (3.3%) were anti-HCV positive. Only seven pregnant women (i.e.(...)
HCV, HIV, Co-infection, Pregnant women, Burkina Faso, Genotype 2a, Mother-to-child transmission