Publications (121)
ARTICLE
Optimization and Standardization of the Extraction Method of Balanites aegyptiaca Del. Seeds (Zygophyllaceae) Used in the Formulation of an Antiparasitic Phytomedicine
Mohamed Bonewendé Belemlilga, Salfo Ouedraogo, Gilchrist Abdoul Laurent Boly, Do Harouna Dao, Jonas Tiami Coulibaly, Jean Claude Romaric Pingdwindé Ouedraogo, Souleymane Compaoré, Sidiki Traore, Moumouni Koala, Estelle Noëla Hoho Youl, Lazare Belemnaba, Félix Bondo Kini, Aristide Traore, Séni Kouanda and Sylvin Ouedraogo
Background/Objectives: Balanites aegyptiaca Del. (Zygophyllaceae) is widely used in traditional medicine, both human and veterinary, throughout Africa for its many properties, including antiparasitic properties. This experimental study aims to optimize the extraction conditions of the seeds of Balanites aegyptiaca Del. Methods: Aqueous macerat(...)
optimization; standardization; Balanites aegyptiaca; antiparasitic phytomedicine
ARTICLE
PROTECTIVE EFFECT OF COMBINATION OF ETHANOLIC EXTRACTS OF XIMENIA AMERICANA AND TERMINALIA MACROPTERA AGAINST ALCOHOL-INDUCED HEPATOTOXICITY IN RATS
Mahamadou Ballo, Sekou Bah, Estelle NH Youl
Objective: The aim of this study was to evaluate the hepatoprotective effect of the combination
Methods: Serum liver markers, tissue antioxidant activity, and histological changes in the livers of rats from the blank, negative (distilled water), positive (silymarin 100 mg/kg bw), and test (combination 500 mg/kg bw) groups were measured after(...)
Antioxidant, Hepatoprotective, Ximenia americana, Terminalia macroptera, Combination$
ARTICLE
Pharmaceutical approaches for enhancing solubility and oral bioavailability of poorly soluble drugs
Isaïe Nyamba , Charles B Sombié, Moussa Yabré , Hermine Zimé-Diawara , Josias Yaméogo , Salfo Ouedraogo , Anna Lechanteur, Rasmané Semdé , Brigitte Evrard
High solubility in water and physiological fluids is an indispensable requirement for the pharmacological efficacy of an active pharmaceutical ingredient. Indeed, it is well established that pharmaceutical substances exhibiting limited solubility in water are inclined towards diminished and inconsistent absorption following oral administration(...)
Formulation, Solubility, Dissolution rate, Bioavailability
COMMUNICATION
Advancing Interprofessional Education in Pharmacy in French-speaking countries: Insights from CIDpharmef Survey
BARDET J-Didier; SCHNEIDER Marie P; KAUFMANN Béatrice; FLORA Luigi; STANDAERT Annie; YOUL Estelle NH; JANOLY-DUMENIL Audrey; VANIER Marie-Claude
The aim of this study was to Identify which Faculties of Pharmacy in the network have implemented IPE training activities and draw up a portrait of these IPE training courses, of the teaching resources and of the expertise available
In 2023, a survey was sent to deans of the 62 Faculties of Pharmacy to identify those offering IPE and map ava(...)
Interprofessional Education, Pharmacy, French-speaking countries, CIDpharmef
ARTICLE
The flavonoid resokaempferol improves insulin secretion from healthy and dysfunctional pancreatic β-cells
Guillaume Gautheron, Sylvie Péraldi-Roux, Justine Vaillé, Sahla Belhadj, Andrzej Patyra, Morgane Bayle, Estelle Youl, Soufiyan Omhmmed, Gérard Cros, Jean-Francois Guichou, Benjamin Uzan, Jérémie Neasta, Catherine Oiry
Background and Purpose: The pharmacology of flavonoids on β-cell function is largely undefined especially in the context of defective secretion of insulin. We sought to identify flavonoids that increased the insulin-secreting function of β-cells and to explore the underlying mechanisms.
Experimental Approach: INS-1 β-cells in culture and isle(...)
flavonoid, resokaempferol, insulin secretion, pancreatic β-cells
ARTICLE
Association de polymères pour le développement de dispersions solides à base d’acide ellagique par extrusion à chaud
Isaïe NYAMBA, Charles B SOMBIE , Hermine ZIME, Josias B.G. YAMÉOGO , Rasmané SEMDE
Dans cette étude, l’extrusion à chaud a été utilisée comme stratégie d’amélioration des
propriétés physicochimiques de l’acide ellagique. En effet, l'acide ellagique est un
composé polyphénolique de classe IV selon la classification biopharmaceutique. Il
possède des propriétés antipaludiques. Cependant, son potentiel thérapeutique reste
in(...)
Acide ellagique, Eudragit EPO, Soluplus, dissolution, dispersions solides
ARTICLE
Potential of Native Cyclodextrins and L-Lysine for Enhancing Ellagic Acid Aqueous Solubility
Isaïe Nyamba, Charles B Sombie, Anna Lechanteur, Rasmané Semde, Brigitte Evrard
This study aimed to examine the influence of β cyclodextrin (βCD) and γ cyclodextrin (γCD) alone and in combination with L-lysine on ellagic acid (EA) solubility. Indeed, complexation with cyclodextrins can be used to improving the solubility of drugs poorly soluble in water such as EA. EA is a Biopharamceutical Classification System (BCS) IV(...)
Antimalarial, L-lysine, Cyclodextrins, Ellagic acid
ARTICLE
Study of harmful vaginal practices of women in the Municipality of Ouagadougou, Burkina Faso
Daniel Dori, Ramata Porgo, Hyacinthe Zamané, Nicolas Méda, Rasmané Semdé
Introduction: Vaginal practices include washing, altering, cutting, cleaning, enhancing, drying, tightening, lubricating, or loosening of the vagina, labia, clitoris, or hymen. This study aimed to investigate the different vaginal practices of women using non-pharmaceutical products. Methodology: This was a cross-sectional study with descripti(...)
Vaginal Practices, Women, Adverse Events
ARTICLE
Systematic Review of Chemical Compounds with Immunomodulatory Action Isolated from African Medicinal Plants
by Wendwaoga Arsène Nikiema ,Moussa Ouédraogo ,Windbedma Prisca Ouédraogo ,Souleymane Fofana ,Boris Honoré Amadou Ouédraogo,Talwendpanga Edwige Delma, Belem Amadé ,Gambo Moustapha Abdoulaye ,Aimé Serge Sawadogo ,Raogo Ouédraogo and Rasmané Semde ,
A robust, well-functioning immune system is the cornerstone of good health. Various factors may influence the immune system’s effectiveness, potentially leading to immune system failure. This review aims to provide an overview of the structure and action of immunomodulators isolated from African medicinal plants. The research was conducted acc(...)
medicinal plants; phytochemicals; immunomodulators; transduction mechanisms
ARTICLE
Chapter 22 - Supercritical fluid methods for liposome production and sterilization
Noémie Penoy, Kouka Luc Delma, Manon Berger, Brigitte Evrard, Géraldine Piel
Despite the numerous laboratory-scale methods available for producing liposomes, only a few are used for commercial manufacturing, delivering liposomes with the necessary critical quality attributes without the use of organic solvents, in Good Manufacturing Practices conditions, and with a low number of unit operations. Similarly, conventional(...)
Mots clés non renseignés
ARTICLE
Etude des connaissances, attitudes et pratiques sur la consommation de tabac des étudiants en sciences de la santé de l’Université Joseph KI-ZERBO
Abdoul Ouadoudou MANDE, Daniel DORI, Kouka Luc DELMA, Bavouma Charles SOMBIE, Rasmané SEMDÉ
Introduction : L’Organisation mondiale de la santé (OMS) estime que la consommation de tabac tue six millions de personnes chaque année. Ses conséquences sur la santé sont multiples. Cependant, il existe peu de données récentes sur le tabagisme des étudiants en sciences de la santé au Burkina Faso. Notre étude a donc pour but d’étudier ce phén(...)
Tabagisme, effets nocifs, attitudes, étudiants
ARTICLE
Study of the Management and Disposal Practices of Unused or Out-of-Date Medicines by Households in the Municipality of Ouagadougou, Burkina Faso
Dori, D., Guembré, A., Ouoba, K., Méda, N. and Semdé, R.
Introduction: Not all medicines that pass-through consumers’ hands are used, and some often expire in households. These health products can be sources of accidental risks and pollution when they are not properly disposed of. In Burkina Faso, there are as yet no guidelines for the disposal of unused medicines in households. The aim of this stud(...)
Unused Medicines, Expired Medicines, Disposal, Household
ARTICLE
Analysis of the conditions for the creation of pharmaceutical university spin-offs within a public university in Burkina Faso
Dori D, Nassouri SG, Toe Djiguimde SLNTM, Ouedraogo R, Semdé R
This study aimed to analyze the legal framework for the creation of university spinoffs, particularly those in the fields of medicine and pharmacy in Burkina Faso. This was carried out through a literature review, supplemented by interviews with resource persons from the sectors in charge of commerce, industry, finance, scientific research and(...)
Spin-off, economic development, research, innovation
ARTICLE
Dengue epidemic in Burkina Faso: concerns about the informal use of traditional herbal remedies
Kampadilemba Ouoba, Daniel Dori, Rasmané Semdé
In response to this latest outbreak of dengue fever, the Ministry of Health and Public Hygiene has undertaken several vector control measures to stop the transmission of this arbovirosis. It has also urged the public to refrain from self-medicating with any suspected symptoms of dengue fever, particularly to avoid using non-steroidal anti-infl(...)
Dengue epidemic, traditional herbal remedies, public health issues
ARTICLE
Pharmacognostical studies and phytochemical evaluation of four Meliaceae plants widely use in ethnomedicine across West Africa.
Aminata P Nacoulma, Yissé Kassoum Combia, Naamwin-So-Bawfu R Meda, Cheick A Noukami Palm, Alain Bambara, Boubacar Yaro and Elie Kabre
Meliaceae plants are widely used in traditional medicine across West Africa, including well-documented
analgesic and anti-inflammatory effects. This study describes assessments for the standardization of
powders from the leaves and bark of these plant materials. Pharmacognostical studies carried out by
macroscopic and microscopic evaluation(...)
Standardization, pharmacognostical studies, phytochemical evaluation