Publications (149)
ARTICLE
Acute toxicity and anti-inflammatory activity of an improved traditional medicine developed in Burkina Faso
Mohamed Bonewendé BELEMLILGA1,3*, Tata Kadiatou TRAORE1, Gilchrist Abdoul Laurent BOLY1, Séripouguin Rihanata BOURGOU1,2, Ladji TRAORE1,2, Salfo OUEDRAOGO1, Jean Claude R. P. OUEDRAOGO1, Sylvain ILBOUDO1,3, Moussa OUEDRAOGO2, Dieudonné KINDA 2, Félix B. KINI1, Aristide TRAORE1, Noufou OUEDRAOGO1,3
practitioners in Burkina Faso as used for hepatoprotective and hepatocurative treatment for viral hepatitis B. The study's main objective was to investigate the anti-inflammatory properties of this ITM, which is used in treating viral hepatitis B in traditional medicine in Burkina Faso. Phytochemical screening revealed the presence of flavonoi(...)
ITM, Phytochemical, Acute toxicity, Anti-inflammatory, Antioxidants
ARTICLE
Pharmaceutical approaches for enhancing solubility and oral bioavailability of poorly soluble drugs
Isaïe Nyamba , Charles B Sombié, Moussa Yabré , Hermine Zimé-Diawara , Josias Yaméogo , Salfo Ouedraogo , Anna Lechanteur, Rasmané Semdé , Brigitte Evrard
High solubility in water and physiological fluids is an indispensable requirement for the pharmacological efficacy of an active pharmaceutical ingredient. Indeed, it is well established that pharmaceutical substances exhibiting limited solubility in water are inclined towards diminished and inconsistent absorption following oral administration(...)
Formulation, Solubility, Dissolution rate, Bioavailability
COMMUNICATION
Advancing Interprofessional Education in Pharmacy in French-speaking countries: Insights from CIDpharmef Survey
BARDET J-Didier; SCHNEIDER Marie P; KAUFMANN Béatrice; FLORA Luigi; STANDAERT Annie; YOUL Estelle NH; JANOLY-DUMENIL Audrey; VANIER Marie-Claude
The aim of this study was to Identify which Faculties of Pharmacy in the network have implemented IPE training activities and draw up a portrait of these IPE training courses, of the teaching resources and of the expertise available
In 2023, a survey was sent to deans of the 62 Faculties of Pharmacy to identify those offering IPE and map ava(...)
Interprofessional Education, Pharmacy, French-speaking countries, CIDpharmef
ARTICLE
Evaluation of the Med Safety mobile app for reporting adverse events in Burkina Faso
Joël Ouoba, Sougrimani Haro‑Lankoandé, Aminata P. Nacoulma, Corinne Simone, Collette Merle, Branwen Johanna Hennig , Souleymane Fofana, Lassané Kaboré, Emile Ouédraogo, Ruth Sawadogo, Sekou Samadoulougou, Fati Kirakoya‑Samadoulougou
Introduction Smartphone applications (apps) for pharmacovigilance present an opportunity for integration as cost-efective
healthcare service intervention into basic healthcare services in low-resource settings. This study aimed to (i) evaluate the
implementation of the Med Safety app in Burkina Faso, and (ii) compare the characteristics of t(...)
Med Safety, reporting adverse events
ARTICLE
Essai de formulation de suppositoires à base d’extraits aqueux des écorces de tronc de Parkia biglobosa jacq. (Fabaceae-Mimosoideae) pour la prise en charge de l’inflammation due à la crise hémorroïdaire
Boladé Constantin ATCHADE, Salfo OUEDRAOGO, Kadiatou Tata TRAORE, Josias B. G YAMEOGO, Charles B. SOMBIE, Hermine ZIME/DIAWARA, Rasmané SEMDE
La maladie hémorroïdaire est un état pathologique caractérisé par une dilatation de la veine recto-anale plexus. Une enquête ethnobotanique a révélé l’utilisation des écorces de tronc de Parkia biglobosa (Jacq.) sous forme de pommade ou décoction en lavement anal pour son traitement. L’objectif de cette étude était de caractériser l’extrait af(...)
Parkia biglobosa, Suppositoires, Activité antioxydante et anti-inflammatoire
ARTICLE
Conditions d’élaboration du Formulaire Thérapeutique au Centre Hospitalier Universitaire Pr Bocar Sidy SALL de Kati
Traoré Mohamed dit Sarmoye, Coulibaly Issa, Traoré Sylvestre, Traoré Alassane, Traore Ousmane, Bah Sékou, Youl Estelle Noëla Hoho
L’objet de ce travail était d’étudier les paramètres à prendre en compte lors de l’élaboration du formulaire thérapeutique du CHU Pr Bocar Sidy SALL de Kati. Il s’agissait d’une étude transversale descriptive. La collecte des données s’est déroulée sur une période de six mois en 2022. Elle a concerné 70 % de l’effectif des médecins prescripteu(...)
Conditions d’élaboration ; Formulaire thérapeutique ; CHU Pr Bocar Sidy SALL
ARTICLE
Traditional, pharmacological uses and phytochemical of 2 annona Review: Annona senegalensis pers and Annona squamosa L.
Mindiediba Jean Bangou, Hermann Yempabou Ouoba, Baguiboe Olivier Bama, Mamadou Sawadogo and Aminata P Nacoulma
The Annonaceae family is widespread and widely used in traditional medicine worldwide. Two species
of this namely Annona senegalensis and Annona squamosa are used in the treatment of breast and
prostate cancers, respiratory diseases, snake and insect bites, rheumatic pains, infertility care and syphilis
to name a few. The aim of this study(...)
Annona senegalensis, Annona squamosa, traditional uses, acetogenins, pharmacological investigations
ARTICLE
The flavonoid resokaempferol improves insulin secretion from healthy and dysfunctional pancreatic β-cells
Guillaume Gautheron, Sylvie Péraldi-Roux, Justine Vaillé, Sahla Belhadj, Andrzej Patyra, Morgane Bayle, Estelle Youl, Soufiyan Omhmmed, Gérard Cros, Jean-Francois Guichou, Benjamin Uzan, Jérémie Neasta, Catherine Oiry
Background and Purpose: The pharmacology of flavonoids on β-cell function is largely undefined especially in the context of defective secretion of insulin. We sought to identify flavonoids that increased the insulin-secreting function of β-cells and to explore the underlying mechanisms.
Experimental Approach: INS-1 β-cells in culture and isle(...)
flavonoid, resokaempferol, insulin secretion, pancreatic β-cells
ARTICLE
Association de polymères pour le développement de dispersions solides à base d’acide ellagique par extrusion à chaud
Isaïe NYAMBA, Charles B SOMBIE , Hermine ZIME, Josias B.G. YAMÉOGO , Rasmané SEMDE
Dans cette étude, l’extrusion à chaud a été utilisée comme stratégie d’amélioration des
propriétés physicochimiques de l’acide ellagique. En effet, l'acide ellagique est un
composé polyphénolique de classe IV selon la classification biopharmaceutique. Il
possède des propriétés antipaludiques. Cependant, son potentiel thérapeutique reste
in(...)
Acide ellagique, Eudragit EPO, Soluplus, dissolution, dispersions solides
ARTICLE
Potential of Native Cyclodextrins and L-Lysine for Enhancing Ellagic Acid Aqueous Solubility
Isaïe Nyamba, Charles B Sombie, Anna Lechanteur, Rasmané Semde, Brigitte Evrard
This study aimed to examine the influence of β cyclodextrin (βCD) and γ cyclodextrin (γCD) alone and in combination with L-lysine on ellagic acid (EA) solubility. Indeed, complexation with cyclodextrins can be used to improving the solubility of drugs poorly soluble in water such as EA. EA is a Biopharamceutical Classification System (BCS) IV(...)
Antimalarial, L-lysine, Cyclodextrins, Ellagic acid
ARTICLE
Study of harmful vaginal practices of women in the Municipality of Ouagadougou, Burkina Faso
Daniel Dori, Ramata Porgo, Hyacinthe Zamané, Nicolas Méda, Rasmané Semdé
Introduction: Vaginal practices include washing, altering, cutting, cleaning, enhancing, drying, tightening, lubricating, or loosening of the vagina, labia, clitoris, or hymen. This study aimed to investigate the different vaginal practices of women using non-pharmaceutical products. Methodology: This was a cross-sectional study with descripti(...)
Vaginal Practices, Women, Adverse Events
ARTICLE
Phytochemical and Pharmacological Properties of Opilia amentacea Roxb (Previously Opilia celtidifolia (Opiliaceae) Guill. Perr.): A Review
Ollo Youl, Gérard Josias Yaméogo, Ernest N. Sombié, Sibidou Yougbaré, Rainatou Boly, Adama Hilou, Maminata Traoré/Coulibaly
The genus Opilia (Opiliaceae) includes only two species: amentacea and campestris. Opilia amentacea Roxb. (O. amentacea), also called Opilia celtidifolia Guill. & Perr) is a West African woody climber plant, a heavily-branched shrub or tree up to 10 m. O. amentacea grows in fringing forests and savannah, often on anthills. It is widespread fro(...)
Opilia amentacea; phytochemistry; pharmacological properties; review
ARTICLE
Systematic Review of Chemical Compounds with Immunomodulatory Action Isolated from African Medicinal Plants
by Wendwaoga Arsène Nikiema ,Moussa Ouédraogo ,Windbedma Prisca Ouédraogo ,Souleymane Fofana ,Boris Honoré Amadou Ouédraogo,Talwendpanga Edwige Delma, Belem Amadé ,Gambo Moustapha Abdoulaye ,Aimé Serge Sawadogo ,Raogo Ouédraogo and Rasmané Semde ,
A robust, well-functioning immune system is the cornerstone of good health. Various factors may influence the immune system’s effectiveness, potentially leading to immune system failure. This review aims to provide an overview of the structure and action of immunomodulators isolated from African medicinal plants. The research was conducted acc(...)
medicinal plants; phytochemicals; immunomodulators; transduction mechanisms
ARTICLE
Chapter 22 - Supercritical fluid methods for liposome production and sterilization
Noémie Penoy, Kouka Luc Delma, Manon Berger, Brigitte Evrard, Géraldine Piel
Despite the numerous laboratory-scale methods available for producing liposomes, only a few are used for commercial manufacturing, delivering liposomes with the necessary critical quality attributes without the use of organic solvents, in Good Manufacturing Practices conditions, and with a low number of unit operations. Similarly, conventional(...)
Mots clés non renseignés
ARTICLE
Etude des connaissances, attitudes et pratiques sur la consommation de tabac des étudiants en sciences de la santé de l’Université Joseph KI-ZERBO
Abdoul Ouadoudou MANDE, Daniel DORI, Kouka Luc DELMA, Bavouma Charles SOMBIE, Rasmané SEMDÉ
Introduction : L’Organisation mondiale de la santé (OMS) estime que la consommation de tabac tue six millions de personnes chaque année. Ses conséquences sur la santé sont multiples. Cependant, il existe peu de données récentes sur le tabagisme des étudiants en sciences de la santé au Burkina Faso. Notre étude a donc pour but d’étudier ce phén(...)
Tabagisme, effets nocifs, attitudes, étudiants