Publications (155)
ARTICLE
Comparison of good review practices of seven countries participating in the ECOWAS medicines regulatory harmonisation initiative: identifying opportunities for improvement
Owusu-Asante M, Darko DM, Seaneke S, Nacoulma A, Traore OIO, Adeyeye CM, Akinyemi A, Assane C, Clamoungou CÉKM, Ndao OK, Kande RN, Komeh J, Mansaray S, Lamboni D, Agba M, Walker S and Salek S
Introduction: When implemented by national and regional regulatory agencies
good review practices (GRevPs) support the timely high-quality review of
medicines for enhanced patients’ availability to safe, quality and efficacious
innovative and generic products. It is important that all aspects of GRevPs are
continuously evaluated and update(...)
Economic Community of West African States Medicines Regulatory Harmonisation (ECOWAS-MRH), good review practices, African Medicines Agency (AMA), regulatory reliance, Optimising Efficiencies in Regulatory Agencies (OpERA)
ARTICLE
Optimization and Standardization of the Extraction Method of Balanites aegyptiaca Del. Seeds (Zygophyllaceae) Used in the Formulation of an Antiparasitic Phytomedicine
Mohamed Bonewendé Belemlilga, Salfo Ouedraogo, Gilchrist Abdoul Laurent Boly, Do Harouna Dao, Jonas Tiami Coulibaly, Jean Claude Romaric Pingdwindé Ouedraogo, Souleymane Compaoré, Sidiki Traore, Moumouni Koala, Estelle Noëla Hoho Youl, Lazare Belemnaba, Félix Bondo Kini, Aristide Traore, Séni Kouanda and Sylvin Ouedraogo
Background/Objectives: Balanites aegyptiaca Del. (Zygophyllaceae) is widely used in traditional medicine, both human and veterinary, throughout Africa for its many properties, including antiparasitic properties. This experimental study aims to optimize the extraction conditions of the seeds of Balanites aegyptiaca Del. Methods: Aqueous macerat(...)
optimization; standardization; Balanites aegyptiaca; antiparasitic phytomedicine
ARTICLE
Guidelines for rational use of drug based data extracted from the APURMED application in Burkina Faso
Tinguéri L. B., Ki A. , Nikiema S., Kafando H. , Bationo B. G., Coulibaly M.1 , Zan I., Rouamba M. , Zoungrana A. B. , Semdé S., Zohoncon T. M., Somé P. C., Bonkoungou V. and Ouédraogo M.
Fortunately, proper use of available medicinal resources could contribute to greater efficiency within
the health system. This study, using data extracted from the APURMED application, aims to guide the
rational use of drugs in practice within Burkina Faso. Treatments for infectious and non-communicable
diseases represent a significant p(...)
APURMED, data extraction, rational use of drug, avoidable risk, Burkina Faso
ARTICLE
Investigation on chemical composition and insecticidal activity against Anopheles gambiae of essential oil obtained by co-distillation of Cymbopogon citratus and Hyptis suaveolens from Western Burkina Faso
Bily Nebié, Constantin M. Dabiré, Remy K. Bationo, Dieudonné D. Soma, Moussa Namountougou, Siaka Sosso, Roger C. H. Nebié, Roch K. Dabiré, Eloi Palé and Pierre Duez
Background Essential oils of Cymbopogon citratus and Hyptis suaveolens are known for their insecticidal propertiesbut remain ineffective against mosquitoes resistant to synthetic insecticides. In order to improve insecticidal properties of these plants, this study aimed to investigate the chemical composition and insecticidal activity against A(...)
Cymbopogon citratus, Hyptis suaveolens, Co-distillation, Essential oil, Insecticidal activity, Resistant Anopheles gambiae
ARTICLE
Development of a digital application for the rational use of medicine in Burkina Faso
Tinguéri L. B.1 , Ki A.2 , Nikiema S.1 , Kafando H.1 , Bationo B. G.3 , Coulibaly M.1 , Zan I.4 , Rouamba M.5 , Zoungrana A. B.1 , Semdé S.1 , Zohoncon T. M. 6,7, Somé P. C.1 , Bonkoungou V. 8 and Ouédraogo M.9
Developing countries lack enough human and financial resources, making it difficult for them to
respond adequately to the population's essential health needs. Using digital applications to promote
the rational use of medicines presents a solution to increase the health system's efficiency and
encourage saving limited medicinal resources.(...)
Digital application, rational use of medicines, drug database, equivalence search option, prescription analysis options.
ARTICLE
PROTECTIVE EFFECT OF COMBINATION OF ETHANOLIC EXTRACTS OF XIMENIA AMERICANA AND TERMINALIA MACROPTERA AGAINST ALCOHOL-INDUCED HEPATOTOXICITY IN RATS
Mahamadou Ballo, Sekou Bah, Estelle NH Youl
Objective: The aim of this study was to evaluate the hepatoprotective effect of the combination
Methods: Serum liver markers, tissue antioxidant activity, and histological changes in the livers of rats from the blank, negative (distilled water), positive (silymarin 100 mg/kg bw), and test (combination 500 mg/kg bw) groups were measured after(...)
Antioxidant, Hepatoprotective, Ximenia americana, Terminalia macroptera, Combination$
ARTICLE
Acute toxicity and anti-inflammatory activity of an improved traditional medicine developed in Burkina Faso
Mohamed Bonewendé BELEMLILGA1,3*, Tata Kadiatou TRAORE1, Gilchrist Abdoul Laurent BOLY1, Séripouguin Rihanata BOURGOU1,2, Ladji TRAORE1,2, Salfo OUEDRAOGO1, Jean Claude R. P. OUEDRAOGO1, Sylvain ILBOUDO1,3, Moussa OUEDRAOGO2, Dieudonné KINDA 2, Félix B. KINI1, Aristide TRAORE1, Noufou OUEDRAOGO1,3
practitioners in Burkina Faso as used for hepatoprotective and hepatocurative treatment for viral hepatitis B. The study's main objective was to investigate the anti-inflammatory properties of this ITM, which is used in treating viral hepatitis B in traditional medicine in Burkina Faso. Phytochemical screening revealed the presence of flavonoi(...)
ITM, Phytochemical, Acute toxicity, Anti-inflammatory, Antioxidants
ARTICLE
Pharmaceutical approaches for enhancing solubility and oral bioavailability of poorly soluble drugs
Isaïe Nyamba , Charles B Sombié, Moussa Yabré , Hermine Zimé-Diawara , Josias Yaméogo , Salfo Ouedraogo , Anna Lechanteur, Rasmané Semdé , Brigitte Evrard
High solubility in water and physiological fluids is an indispensable requirement for the pharmacological efficacy of an active pharmaceutical ingredient. Indeed, it is well established that pharmaceutical substances exhibiting limited solubility in water are inclined towards diminished and inconsistent absorption following oral administration(...)
Formulation, Solubility, Dissolution rate, Bioavailability
COMMUNICATION
Advancing Interprofessional Education in Pharmacy in French-speaking countries: Insights from CIDpharmef Survey
BARDET J-Didier; SCHNEIDER Marie P; KAUFMANN Béatrice; FLORA Luigi; STANDAERT Annie; YOUL Estelle NH; JANOLY-DUMENIL Audrey; VANIER Marie-Claude
The aim of this study was to Identify which Faculties of Pharmacy in the network have implemented IPE training activities and draw up a portrait of these IPE training courses, of the teaching resources and of the expertise available
In 2023, a survey was sent to deans of the 62 Faculties of Pharmacy to identify those offering IPE and map ava(...)
Interprofessional Education, Pharmacy, French-speaking countries, CIDpharmef
ARTICLE
Evaluation of the Med Safety mobile app for reporting adverse events in Burkina Faso
Joël Ouoba, Sougrimani Haro‑Lankoandé, Aminata P. Nacoulma, Corinne Simone, Collette Merle, Branwen Johanna Hennig , Souleymane Fofana, Lassané Kaboré, Emile Ouédraogo, Ruth Sawadogo, Sekou Samadoulougou, Fati Kirakoya‑Samadoulougou
Introduction Smartphone applications (apps) for pharmacovigilance present an opportunity for integration as cost-efective
healthcare service intervention into basic healthcare services in low-resource settings. This study aimed to (i) evaluate the
implementation of the Med Safety app in Burkina Faso, and (ii) compare the characteristics of t(...)
Med Safety, reporting adverse events
ARTICLE
Essai de formulation de suppositoires à base d’extraits aqueux des écorces de tronc de Parkia biglobosa jacq. (Fabaceae-Mimosoideae) pour la prise en charge de l’inflammation due à la crise hémorroïdaire
Boladé Constantin ATCHADE, Salfo OUEDRAOGO, Kadiatou Tata TRAORE, Josias B. G YAMEOGO, Charles B. SOMBIE, Hermine ZIME/DIAWARA, Rasmané SEMDE
La maladie hémorroïdaire est un état pathologique caractérisé par une dilatation de la veine recto-anale plexus. Une enquête ethnobotanique a révélé l’utilisation des écorces de tronc de Parkia biglobosa (Jacq.) sous forme de pommade ou décoction en lavement anal pour son traitement. L’objectif de cette étude était de caractériser l’extrait af(...)
Parkia biglobosa, Suppositoires, Activité antioxydante et anti-inflammatoire
ARTICLE
Conditions d’élaboration du Formulaire Thérapeutique au Centre Hospitalier Universitaire Pr Bocar Sidy SALL de Kati
Traoré Mohamed dit Sarmoye, Coulibaly Issa, Traoré Sylvestre, Traoré Alassane, Traore Ousmane, Bah Sékou, Youl Estelle Noëla Hoho
L’objet de ce travail était d’étudier les paramètres à prendre en compte lors de l’élaboration du formulaire thérapeutique du CHU Pr Bocar Sidy SALL de Kati. Il s’agissait d’une étude transversale descriptive. La collecte des données s’est déroulée sur une période de six mois en 2022. Elle a concerné 70 % de l’effectif des médecins prescripteu(...)
Conditions d’élaboration ; Formulaire thérapeutique ; CHU Pr Bocar Sidy SALL
ARTICLE
Traditional, pharmacological uses and phytochemical of 2 annona Review: Annona senegalensis pers and Annona squamosa L.
Mindiediba Jean Bangou, Hermann Yempabou Ouoba, Baguiboe Olivier Bama, Mamadou Sawadogo and Aminata P Nacoulma
The Annonaceae family is widespread and widely used in traditional medicine worldwide. Two species
of this namely Annona senegalensis and Annona squamosa are used in the treatment of breast and
prostate cancers, respiratory diseases, snake and insect bites, rheumatic pains, infertility care and syphilis
to name a few. The aim of this study(...)
Annona senegalensis, Annona squamosa, traditional uses, acetogenins, pharmacological investigations
ARTICLE
The flavonoid resokaempferol improves insulin secretion from healthy and dysfunctional pancreatic β-cells
Guillaume Gautheron, Sylvie Péraldi-Roux, Justine Vaillé, Sahla Belhadj, Andrzej Patyra, Morgane Bayle, Estelle Youl, Soufiyan Omhmmed, Gérard Cros, Jean-Francois Guichou, Benjamin Uzan, Jérémie Neasta, Catherine Oiry
Background and Purpose: The pharmacology of flavonoids on β-cell function is largely undefined especially in the context of defective secretion of insulin. We sought to identify flavonoids that increased the insulin-secreting function of β-cells and to explore the underlying mechanisms.
Experimental Approach: INS-1 β-cells in culture and isle(...)
flavonoid, resokaempferol, insulin secretion, pancreatic β-cells
ARTICLE
Association de polymères pour le développement de dispersions solides à base d’acide ellagique par extrusion à chaud
Isaïe NYAMBA, Charles B SOMBIE , Hermine ZIME, Josias B.G. YAMÉOGO , Rasmané SEMDE
Dans cette étude, l’extrusion à chaud a été utilisée comme stratégie d’amélioration des
propriétés physicochimiques de l’acide ellagique. En effet, l'acide ellagique est un
composé polyphénolique de classe IV selon la classification biopharmaceutique. Il
possède des propriétés antipaludiques. Cependant, son potentiel thérapeutique reste
in(...)
Acide ellagique, Eudragit EPO, Soluplus, dissolution, dispersions solides