Publications (234)
ARTICLE
Overview of regulations on medicines derived from traditional Pharmacopoeia in Benin and Burkina Faso
Dori D, Ganfon H, Gbaguidi F, Evrard B, Leclercq JQ, Semdé R
The success of the promotion policies of the Medicines Derived from Traditional Pharmacopoeia (MDTPs) requires a regulation that is adapted to realities and guarantees their quality, efficiency and safeness. This study aims to analyze the legal texts and the current guiding principles obtained from the heads of the departments in charge of tra(...)
WHO, MDTPs, WAEMU, WAHO, Traditional medicine, medicine, regulation, Burkina Faso
ARTICLE
Antioxidant properties and subchronic toxicity of the standardized extract of LAMIC, a phytomedicine prototype based on aqueous extracts from trunk bark of Lannea microcarpa Engl and K. Krause
Lazare Belemnaba, Madi Soubeiga, Geoffroy Gueswindé Ouédraogo, Tata Kadiatou Traoré, Mathieu Nitiéma, Sylvain Ilboudo, B. Mohamed Belemlilga, Souleymane Compaoré, Raïnatou Sondé Boly, Jean Claude Romaric Pingdwindé Ouédraogo, Salfo Ouédraogo, Alphonsine Ramdé Tiendrebéogo, Noufou Ouédraogo, Moussa Ouédraogo, Sylvin Ouédraogo
Aims:This study investigated the antioxidant activity and the 90 days subchronictoxicity of the standardized LAMIC phytomedicine prototype based on aqueous extracts from Lannea microcarpatrunk bark.Methods:Three spectrophotometric methods were used to evaluated the antioxidant activity of LAMIC which were 2,2-Diphen(...)
LAMIC–Lannea microcarpa–Standardization–Antioxidant–Subchronic toxicity.
ARTICLE
Tolerance and observance of methotrexate in the treatment of rheumatoid arthritis at the university Hospital Bogodogo, Burkina Faso.
R. Frank E. Zongo, Joelle S. Zabsonré , Aminata Nacoulma , Souleymane Fofana , Moise W. Sawadogo , Estelle Noëla Hoho YOUL, Moussa Ouédraogo and Dieu-Donné Ouédraogo
This study is aimed at assessing tolerance and observance of the patients with RA (rheumatoid arthritis) treated by methotrexate at University Hospital Bogodogo, in Burkina Faso. A cross-sectional study was conducted from July to September 2015 in outpatients with rheumatoid arthritis monitored in rheumatology service. Data were obtained from(...)
Rheumatoid arthritis, observance, methotrexate, tolerance, Burkina Faso.
ARTICLE
The ellagitannin metabolite urolithin C is a glucose‐dependent regulator of insulin secretion through activation of L‐type calcium channels
Morgane Bayle, Jérémie Neasta, Margherita Dall'Asta, Guillaume Gautheron, Anne Virsolvy, Jean‐François Quignard, Estelle Youl, Richard Magous, Jean‐François Guichou, Alan Crozier, Daniele Del Rio, Gérard Cros, Catherine Oiry
Background and Purpose: The pharmacology of polyphenol metabolites on beta‐ cell function is largely undetermined. We sought to identify polyphenol metabolites that enhance the insulin‐secreting function of beta‐cells and to explore the underlying mechanisms.
Experimental Approach: INS‐1 beta‐cells and rat isolated islets of Langerhans or per(...)
ellagitannin, urolithin C, glucose‐dependent regulator, insulin secretion, L‐type calcium channels
ARTICLE
Pharmacological study of trunk bark of Acacia nilotica var adansonii (Guill et Perr).o Ktze (Mimosaceae): Assays, antioxidant and antispasmodic activities
Gilchrist L Boly Abdoul, Aristide Traoré, Moussa Ouédraogo, Mohamed Bonewendé Belemlilga, Tata Kadiatou Traoré, Lazare Belemnaba, Noufou Ouédraogo, Andre Lupu, Sylvin Ouédraogo, Mirn Liviu O, Innocent Pierre Guissou
Aim of this study was to evaluate in vitro polyphenols content, antioxidant and antispasmodic properties of the aqueous extract and fractions of the trunk bark of Acacia nilotica. According to a survey conducted in rural Burkina Faso, Acacia nilotica var. adansonii (Guill and Perr). Ktze reported to be widely used in the treatment of gastroint(...)
Antispasmodic, Ethyl acetate, Traditional medicine, DPPH, Bark (sound), Chemistry, Polyphenol, Antioxidant, Butanol, Acacia, Chromatography, Botany, Biochemistry, Biology, Medicine, Ethanol
ARTICLE
Antioxidant activity of crude ethanolic extract and fractions of Ziziphus mauritiana Lam. (Rhamnaceae) leaves from Burkina Faso.
Estelle Noëla Hoho YOUL, Cyrille A.P. Ouédraogo, Moustapha Gambo, Moussa Ouédraogo, Martin Kiendrebéogo, Aristide Traoré, Innocent Pierre Guissou
Background: Ziziphus mauritiana Lam. is a plant used in traditional medicine in Burkina Faso in the treatment of several diseases, of which diabetes is characterized by oxidative stress. The aim of this study was to evaluate the in vitro antioxidant potential of the extracts of leaves of this plant.
Methods: The crude hydroethanolic extract ((...)
antioxidant activity, polyphenol content, Ziziphus mauritiana
ARTICLE
Evaluation of some quality parameters of crude shea butter produced in Burkina Faso
Wendinmi Bertrand Goumbri, Touridomon Issa Somé, Roland Marini Djang'Eing'A, Giorgia Purcaro, Sabine Danthine
Gross composition and physicochemical properties of shea butter (SB) widely vary depending on geographical origin, cultivars and extraction process. This study aims at characterizing the composition of crude SB collected in Burkina Faso, with a particular interest for the unsaponifiable. Results concerns five samples, all obtained by tradition(...)
Quality (philosophy), Business, Food science, Agricultural science, Environmental science, Chemistry
ARTICLE
Larvicidal Activity of Crude Extracts of Vernonia cinerea Less (Asteraceae) against the Larvae of Anopheles gambiae in Bobo Dioulasso, Burkina Faso
Aboubakar Soma, François Hien, Seydou Sourabié, Serge Yerbanga, Léa Nadège Bonkian, Benjamin K. Koama, Noufou Ouédraogo, Moussa Ouédraogo, Etienne Bilgo, Mamoudou Cissé, Gordon A. Awandare, Jean-Baptiste Nikiéma
Abstract
Aims: This study aims to evaluate the larvicidal activity of lyophilized methanolic extracts, hydro-methanolic extracts and aqueous extracts of Vernonia cinerea Less against the 3rd and 4th instars larvae of Anopheles gambiae.
Place and Duration of Study: Pharmacognosy Laboratory, Department of Biomedical Sciences, Centre MURAZ /R(...)
Vernonia cinerea Less, Anopheles gambiae, larvicidal activity, malaria, Banfora, Bobo-Dioulasso, Burkina Faso
ARTICLE
Plaidoyer pour un renforcement du système de pharmacovigilance au Burkina Faso
Lassané Kaboré, Tènè Marceline Yaméogo, Issiaka Sombié, Moussa Ouédraogo, Souleymane Fofana, Abdramane Berthé, Rasmané Semdé, Fati Kirakoya‐Samadoulougou
Dans de nombreux pays d’Afrique subsaharienne qui sont confrontés à des problèmes majeurs de santé publique comme le paludisme et le VIH, un déploiement massif de nouveaux
médicaments a été observé au cours des deux dernières décennies. Or, certains de ces médicaments comportent une toxicité plus ou moins importante, pouvant entraîner une bai(...)
Pharmacovigilance, Political science, Humanities, Medicine, Philosophy, Drug, Pharmacology
ARTICLE
Descriptive Study of Acute Poisoning Cases Admitted to Yalgado Ouédraogo University Hospital in Ouagadougou, Burkina Faso
Salimata Traoré, Touridomon Issa Somé, Assita Lamien Sanou, Alphonse Yakoro, Pierre I. Guissou
Background: To analyze the features of the acute poisoning cases admitted to Yalgado Ouedraogo University Hospital (CHU) in Ouagadougou. Methods: It is a prospective study conducted in 2014. All the poisoning cases admitted to the Medical and Paediatric Emergency services in Yalgado Ouedraogo University Hospital (CHU) in Ouagadougou since Janu(...)
Medicine, University hospital, Accidental, Emergency department, Physical examination, Occupational safety and health, General surgery, Emergency medicine, Medical emergency, Surgery, Nursing
ARTICLE
Rosuvastatin and vascular oxidative stress induced by diesel exhaust particles
athalie Labranche , Estelle N. H. Youl , Charaf El Khattabi , Laurence Dewachter , Nathalie Wauthoz , Cédric Delporte , Guy Berkenboom & Stéphanie Pochet,
Objective Exposure to diesel exhaust particles (DEP) is strongly linked to the development and exacerbation of cardiovascular diseases. Statins are effective drugs in the prevention and treatment of cardiovascular disorders. The aim of this study was to investigate the potential protective effect of rosuvastatin on DEP-induced endothelial dysf(...)
Diesel exhaust particles, oxidative stress, statins, eNOS, NADPH oxidase
ARTICLE
POLYMORPHISME GENETIQUE DES CYTOCHROMES P450 : SYNTHESE METHODIQUE DES ETUDES PRIMAIRES EFFECTUEES DANS LA POPULATION AFRICAINE
ELIE KABRE, RAOUL KARFO, BOUKARE KASSONGO, JEAN SAKANDE , MAMADOU SAWADOGO
Il existe une grande variabilité interindividuelle de réponse aux médicaments, tant en terme d’efficacité que de toxicité. Pour comprendre cette variabilité, de multiples travaux de recherche sur le polymorphisme génétique des cytochromes P450 ont été menés de par le monde. Notre étude a pour but de faire le point des études réalisées en Afri(...)
: Pharmacogénétique, Polymorphisme, Cytochromes P450
ARTICLE
PRÉVALENCE ET CARACTÉRISTIQUES DES UTILISATIONS HORS MONOGRAPHIE DES MÉDICAMENTS EN PÉDIATRIE AU CENTRE HOSPITALIER UNIVERSITAIRE YALGADO OUÉDRAOGO (CHUYO), BURKINA FASO
ZONGO R. F. E ., DIALLO I., OUEDRAOGO S., BOUDA C. G., GAMBO O., YOUL N. E., GUISSOU I. P.
Introduction: l'usage du médicament en pédiatrie n'est pas toujours en accord avec la monographie approuvée par l'autorisation de mise sur le marché. La présente étude vise à déterminer la prévalence des utilisations hors monographie des médicaments dans le département de pédiatrie du CHUYO et de les décrire.
Méthodes: Une étude rétrospective(...)
Approbation du médicament, Monographie, Pédiatrie, Utilisation hors monographie
ARTICLE
ANALYSE DES ORDONNANCES MÉDICALES AU CENTRE HOSPITALIER UNIVERSITAIRE YALGADO OUEDRAOGO DE OUAGADOUGOU
FOFANA S., ZONGO F. E., ZOUNGRANA P. M., OUEDRAOGO M., YOUL E., GNOULA C., SONDE I., GUISSOU I. P.
Introduction
La prescription des médicaments est un acte médical spécialisé. De loi des médicaments. Afin de s au CHU YO, nous avons analysé la conformité règlementaire et technique des ordonnances médicales prescrites.
Méthodologie
Il s'agit d'une étude transversale descriptive menée entre avril et mai 2012 à l'officine pharmaceutique du C(...)
Prescription médicale; Pharmacie hospitalière; CHU- YO; Burkina Faso.
COMMUNICATION
Expérience du Burkina Faso en matière de pharmacovigilance
E. W. Ouédraogo1, E. Da/Nacoulma1, F. E. Zongo2, C. R. Ouandaogo3
Titre : Expérience du Burkina Faso en matière de pharmacovigilance
Auteurs : E. W. Ouédraogo1, E. Da/Nacoulma1, F. E. Zongo2, C. R. Ouandaogo3.
Introduction
Conformément à la résolution WHA.16.36 (16ème assemblée mondiale de la santé) de 1963, le Burkina Faso s’est engagé résolument en 2006 à la faveur de l’introduction des ACT dans la pri(...)
Pharmacovigilance, Burkina Faso