Publications (226)
ARTICLE
Plaidoyer pour un renforcement du système de pharmacovigilance au Burkina Faso
Lassané Kaboré, Tènè Marceline Yaméogo, Issiaka Sombié, Moussa Ouédraogo, Souleymane Fofana, Abdramane Berthé, Rasmané Semdé, Fati Kirakoya‐Samadoulougou
Dans de nombreux pays d’Afrique subsaharienne qui sont confrontés à des problèmes majeurs de santé publique comme le paludisme et le VIH, un déploiement massif de nouveaux
médicaments a été observé au cours des deux dernières décennies. Or, certains de ces médicaments comportent une toxicité plus ou moins importante, pouvant entraîner une bai(...)
Pharmacovigilance, Political science, Humanities, Medicine, Philosophy, Drug, Pharmacology
ARTICLE
Descriptive Study of Acute Poisoning Cases Admitted to Yalgado Ouédraogo University Hospital in Ouagadougou, Burkina Faso
Salimata Traoré, Touridomon Issa Somé, Assita Lamien Sanou, Alphonse Yakoro, Pierre I. Guissou
Background: To analyze the features of the acute poisoning cases admitted to Yalgado Ouedraogo University Hospital (CHU) in Ouagadougou. Methods: It is a prospective study conducted in 2014. All the poisoning cases admitted to the Medical and Paediatric Emergency services in Yalgado Ouedraogo University Hospital (CHU) in Ouagadougou since Janu(...)
Medicine, University hospital, Accidental, Emergency department, Physical examination, Occupational safety and health, General surgery, Emergency medicine, Medical emergency, Surgery, Nursing
ARTICLE
Rosuvastatin and vascular oxidative stress induced by diesel exhaust particles
athalie Labranche , Estelle N. H. Youl , Charaf El Khattabi , Laurence Dewachter , Nathalie Wauthoz , Cédric Delporte , Guy Berkenboom & Stéphanie Pochet,
Objective Exposure to diesel exhaust particles (DEP) is strongly linked to the development and exacerbation of cardiovascular diseases. Statins are effective drugs in the prevention and treatment of cardiovascular disorders. The aim of this study was to investigate the potential protective effect of rosuvastatin on DEP-induced endothelial dysf(...)
Diesel exhaust particles, oxidative stress, statins, eNOS, NADPH oxidase
ARTICLE
POLYMORPHISME GENETIQUE DES CYTOCHROMES P450 : SYNTHESE METHODIQUE DES ETUDES PRIMAIRES EFFECTUEES DANS LA POPULATION AFRICAINE
ELIE KABRE, RAOUL KARFO, BOUKARE KASSONGO, JEAN SAKANDE , MAMADOU SAWADOGO
Il existe une grande variabilité interindividuelle de réponse aux médicaments, tant en terme d’efficacité que de toxicité. Pour comprendre cette variabilité, de multiples travaux de recherche sur le polymorphisme génétique des cytochromes P450 ont été menés de par le monde. Notre étude a pour but de faire le point des études réalisées en Afri(...)
: Pharmacogénétique, Polymorphisme, Cytochromes P450
ARTICLE
PRÉVALENCE ET CARACTÉRISTIQUES DES UTILISATIONS HORS MONOGRAPHIE DES MÉDICAMENTS EN PÉDIATRIE AU CENTRE HOSPITALIER UNIVERSITAIRE YALGADO OUÉDRAOGO (CHUYO), BURKINA FASO
ZONGO R. F. E ., DIALLO I., OUEDRAOGO S., BOUDA C. G., GAMBO O., YOUL N. E., GUISSOU I. P.
Introduction: l'usage du médicament en pédiatrie n'est pas toujours en accord avec la monographie approuvée par l'autorisation de mise sur le marché. La présente étude vise à déterminer la prévalence des utilisations hors monographie des médicaments dans le département de pédiatrie du CHUYO et de les décrire.
Méthodes: Une étude rétrospective(...)
Approbation du médicament, Monographie, Pédiatrie, Utilisation hors monographie
ARTICLE
ANALYSE DES ORDONNANCES MÉDICALES AU CENTRE HOSPITALIER UNIVERSITAIRE YALGADO OUEDRAOGO DE OUAGADOUGOU
FOFANA S., ZONGO F. E., ZOUNGRANA P. M., OUEDRAOGO M., YOUL E., GNOULA C., SONDE I., GUISSOU I. P.
Introduction
La prescription des médicaments est un acte médical spécialisé. De loi des médicaments. Afin de s au CHU YO, nous avons analysé la conformité règlementaire et technique des ordonnances médicales prescrites.
Méthodologie
Il s'agit d'une étude transversale descriptive menée entre avril et mai 2012 à l'officine pharmaceutique du C(...)
Prescription médicale; Pharmacie hospitalière; CHU- YO; Burkina Faso.
COMMUNICATION
Expérience du Burkina Faso en matière de pharmacovigilance
E. W. Ouédraogo1, E. Da/Nacoulma1, F. E. Zongo2, C. R. Ouandaogo3
Titre : Expérience du Burkina Faso en matière de pharmacovigilance
Auteurs : E. W. Ouédraogo1, E. Da/Nacoulma1, F. E. Zongo2, C. R. Ouandaogo3.
Introduction
Conformément à la résolution WHA.16.36 (16ème assemblée mondiale de la santé) de 1963, le Burkina Faso s’est engagé résolument en 2006 à la faveur de l’introduction des ACT dans la pri(...)
Pharmacovigilance, Burkina Faso
ARTICLE
Determination of groundwater mercury (II) content using a disposable gold modified screen printed carbon electrode
Touridomon Issa Some, Abdoul Karim Sakira, Dominique Mertens, Sebastien N. Ronkartand Jean-Michel Kauffmann
Mercury (II) measurements were performed thanks to a newly developed electrochemical method using a disposable gold modified screen printed carbon electrode. The method has a wide dynamic range (1–100 µg/L), a good accuracy and a limit of detection in compliance with WHO standards. The application of the method to several groundwater samples m(...)
Mots clés non renseignés
COMMUNICATION
Using new vaccine introduction as entry point for strengthening AEFI surveillance systems Lessons learned with MenAfriVac® in Burkina Faso
Dr Emile W. OUEDRAOGO
Dr Emile Ouédraogo of Burkina Faso reported how the introduction of a new vaccine – the meningitis vaccine MenAfriVac – provided an opportunity to strengthen the country’s AEFI surveillance system. Prior to this, training on spontaneous reporting of adverse drug reactions for malaria and HIV/TB medicines had been funded by the Global Fund, and(...)
AEFI, Vaccine, Burkina Faso, MenAfrivac
ARTICLE
MAP Kinase cross talks in oxidative stress-induced impairment of insulin secretion. Involvement in the protective activity of quercetin
Estelle Youl, Richard Magous, Gerard Cros, Catherine Oiry
Insulin secretion preservation is a major issue for the prevention or treatment of type 2 diabetes. We previously showed on b-cells that quercetin (Q), but not resve- ratrol (R) or N-acetyl cysteine (NAC), amplified glucose-induced insulin secretion in a calcium- and ERK1/2-dependent manner. Quercetin, but not resveratrol or NAC, also protecte(...)
Insulin secretion, MAP kinase cross talks, oxidative stress, quercetin, b-cell
ARTICLE
Determination of arsenic (III) at a nanogold modified solid carbon paste electrode
Abdoul Karim Sakira, Touridomon Issa Some, Bieke Dejaegher, Dominique Mertens, Philippe Hubert, Eric M Ziemons and Jean‐Michel Kauffmann
A selective and sensitive electroanalytical method was developed for arsenic determination based on a nanogold (AuNP) modified solid carbon paste working electrode (SCPE) modified in two steps (i) physisorption and (ii) additional electrodeposition of nanogold particles in the presence of iodide. Copper (II) interference was solved by covering(...)
Mots clés non renseignés
ARTICLE
Determination of β-carotene by High Performance Liquid Chromatography in Six Varieties of Mango (Mangifera indica L) from Western Region of Burkina Faso
Touridomon Issa Somé, Abdoul Karim Sakira and Eric Dofinizoumou Tamimi
Six varieties of mangoes (Amelia, Brooks, Kent, Keitt, Lippens, Springfield) harvested from different pedological areas of the western region of Burkina Faso (Bobo-Dioulasso, Orodara, Banfora) were analyzed by high performance liquid chromatography in order to determine the β-carotene content. The study revealed a variability in β-carotene con(...)
Mots clés non renseignés
ARTICLE
Effect of cyclodextrins on artemisinin stability and in vitro dissolution
H Zime-Diawara, F Gbaguidi, R Semde, I Some, J Quetin-Leclercq, M Moudachirou, G Piel and B Evrard
Artemisinin is extracted from the Asian plant Artemisia annua L. It has been proven to be, with its derivatives, the molecules that have shown so far the most powerful activity on malaria, even in its complicated forms and resistance cases. To resolve the problem of low aqueous solubility of this molecule, the use of cyclodextrins (CDs) was en(...)
Mots clés non renseignés
ARTICLE
Study of Antisickling and Vasorelaxant Activities and Acute Toxicity Assessment of Crude Extracts of Leaves of Ficus sycomorus L. (Moraceae)
Alphonsine Ramde-Tien, André Tibiri, Moussa Ouédraogo, Sylvin Ouedraogo ., Odile Germaine Nacou ., Innocent Pierre Guis .
The leaves of Ficus sycomorus are used in Burkina Faso folk medicine for the treatment of sickle cell disease. The present comparative study of crude extracts of leaves (decoction, macerated extract and a 95% ethanol extract) was performed with the aim to assess the efficiency of this traditional use and to determine the most active of the thr(...)
Acute toxicity, Moraceae, Decoction, Traditional medicine, Crude drug, Chemistry, Pharmacology, Toxicity, Medicine
ARTICLE
A Survey of Arsenic Level in Tube-Wells in Bam Province (Burkina Faso)
Touridomon Issa Somé, Abdoul Karim Sakira, Alidou Kaboré, Aissata Traoré
Groundwater is a main source of water supply for populations in Burkina Faso where there is a serious problem for drinking water access. However, water quality has not been always followed regularly. Recent studies showed that more than 50% of drillings in Yatenga province (north of Burkina Faso) have an arsenic concentration above the recomme(...)
Arsenic, Groundwater, Environmental science, Water supply, Arsenic contamination of groundwater, Water well, Water quality, Environmental engineering, Water source, Water resource management, Geography, Environmental protection, Engineering, Chemistry