Publications (201)
ARTICLE
Contribution of clinical pharmacy to the rational and safe use of medicines in the neonatology unit of the pediatric university hospital Charles de Gaulle of Ouagadougou, Burkina Faso
Moussa Ouedraogo, Bonsdawindé Pagbelguem, Arsène Wendwaoga Nikiema, Charles B. Sombié, Emile W. Ouedraogo, Colette Zoungrana, Kisito Nagalo, Aïssata Kabore
Background: Newborns are exposed to drug therapeutic risks due to off-label prescribing and immaturity. The purpose of this study is to identify drug-related problems through the prescription and administration of drugs in the neonatology Unit and identify the need for pharmaceutical interventions.
Methods: To assess drug-related problems, a(...)
Neonatology, Drug-related problem, Medicines prescription and administration, Burkina Faso
ARTICLE
Comparison of good review practices of seven countries participating in the ECOWAS medicines regulatory harmonisation initiative: identifying opportunities for improvement
Owusu-Asante M, Darko DM, Seaneke S, Nacoulma A, Traore OIO, Adeyeye CM, Akinyemi A, Assane C, Clamoungou CÉKM, Ndao OK, Kande RN, Komeh J, Mansaray S, Lamboni D, Agba M, Walker S and Salek S
Introduction: When implemented by national and regional regulatory agencies
good review practices (GRevPs) support the timely high-quality review of
medicines for enhanced patients’ availability to safe, quality and efficacious
innovative and generic products. It is important that all aspects of GRevPs are
continuously evaluated and update(...)
Economic Community of West African States Medicines Regulatory Harmonisation (ECOWAS-MRH), good review practices, African Medicines Agency (AMA), regulatory reliance, Optimising Efficiencies in Regulatory Agencies (OpERA)
ARTICLE
Impacts of SAYE PLUS , an Antimalarial Phytomedicine With Potential Anti‐COVID‐19, on the Physical, Biological, and Genotoxicity Parameters of Rodents in Short‐Term Toxicity Studies
Joël Ouédraogo, Sylvain Ilboudo, Geoffroy Gueswindé Ouédraogo, Virginie Dakuyo, Salfo OUEDRAOGO, Gaëtan Donzéo SOMDA, Jean Claude Romaric Pingdwindé Ouédraogo, Moussa Ouédraogo, Rasmané Semdé, Sylvin Ouédraogo
In response to the COVID-19 pandemic and following the World Health Organization's call for action, several traditional medicine recipes were used without any scientific prerequisites concerning their safety. The current study investigated several short-term toxicity parameters of SAYE PLUS, an antimalarial phytomedicine used in COVID-19 patie(...)
Phytomedicine, Toxicity, Medicine, No-observed-adverse-effect level, Acute toxicity, Pharmacology, Genotoxicity, Physiology, Median lethal dose, Toxicology, Traditional medicine, Internal medicine, Biology
ARTICLE
Optimization and Standardization of the Extraction Method of Balanites aegyptiaca Del. Seeds (Zygophyllaceae) Used in the Formulation of an Antiparasitic Phytomedicine
Mohamed Bonewendé Belemlilga, Salfo Ouedraogo, Gilchrist Abdoul Laurent Boly, Do Harouna Dao, Jonas Tiami Coulibaly, Jean Claude Romaric Pingdwindé Ouedraogo, Souleymane Compaoré, Sidiki Traore, Moumouni Koala, Estelle Noëla Hoho Youl, Lazare Belemnaba, Félix Bondo Kini, Aristide Traore, Séni Kouanda and Sylvin Ouedraogo
Background/Objectives: Balanites aegyptiaca Del. (Zygophyllaceae) is widely used in traditional medicine, both human and veterinary, throughout Africa for its many properties, including antiparasitic properties. This experimental study aims to optimize the extraction conditions of the seeds of Balanites aegyptiaca Del. Methods: Aqueous macerat(...)
optimization; standardization; Balanites aegyptiaca; antiparasitic phytomedicine
ARTICLE
Guidelines for rational use of drug based data extracted from the APURMED application in Burkina Faso
Tinguéri L. B., Ki A. , Nikiema S., Kafando H. , Bationo B. G., Coulibaly M.1 , Zan I., Rouamba M. , Zoungrana A. B. , Semdé S., Zohoncon T. M., Somé P. C., Bonkoungou V. and Ouédraogo M.
Fortunately, proper use of available medicinal resources could contribute to greater efficiency within
the health system. This study, using data extracted from the APURMED application, aims to guide the
rational use of drugs in practice within Burkina Faso. Treatments for infectious and non-communicable
diseases represent a significant p(...)
APURMED, data extraction, rational use of drug, avoidable risk, Burkina Faso
ARTICLE
Investigation on chemical composition and insecticidal activity against Anopheles gambiae of essential oil obtained by co-distillation of Cymbopogon citratus and Hyptis suaveolens from Western Burkina Faso
Bily Nebié, Constantin M. Dabiré, Remy K. Bationo, Dieudonné D. Soma, Moussa Namountougou, Siaka Sosso, Roger C. H. Nebié, Roch K. Dabiré, Eloi Palé and Pierre Duez
Background Essential oils of Cymbopogon citratus and Hyptis suaveolens are known for their insecticidal propertiesbut remain ineffective against mosquitoes resistant to synthetic insecticides. In order to improve insecticidal properties of these plants, this study aimed to investigate the chemical composition and insecticidal activity against A(...)
Cymbopogon citratus, Hyptis suaveolens, Co-distillation, Essential oil, Insecticidal activity, Resistant Anopheles gambiae
ARTICLE
Evaluation of acute and subacute toxicity and sedative effect of Feretia apodanthera Delile (Rubiaceae) leaves
Gniènèfèrètien Nounaféri Awa Silué, Sylvain Ilboudo, Lenoir Thierry Ayoman Djadji, Geoffroy Ouedraogo, Mohamed Bonewendé Belemlilga, Gisèle Kouakou-Siransy, Rasmané Semdé
Evaluation of acute and subacute toxicity and sedative effect of Feretia apodanthera Delile (Rubiaceae) leaves)
Feretia apodanthera Delile, toxicity, sedative effects
ARTICLE
Development of a digital application for the rational use of medicine in Burkina Faso
Tinguéri L. B.1 , Ki A.2 , Nikiema S.1 , Kafando H.1 , Bationo B. G.3 , Coulibaly M.1 , Zan I.4 , Rouamba M.5 , Zoungrana A. B.1 , Semdé S.1 , Zohoncon T. M. 6,7, Somé P. C.1 , Bonkoungou V. 8 and Ouédraogo M.9
Developing countries lack enough human and financial resources, making it difficult for them to
respond adequately to the population's essential health needs. Using digital applications to promote
the rational use of medicines presents a solution to increase the health system's efficiency and
encourage saving limited medicinal resources.(...)
Digital application, rational use of medicines, drug database, equivalence search option, prescription analysis options.
ARTICLE
PROTECTIVE EFFECT OF COMBINATION OF ETHANOLIC EXTRACTS OF XIMENIA AMERICANA AND TERMINALIA MACROPTERA AGAINST ALCOHOL-INDUCED HEPATOTOXICITY IN RATS
Mahamadou Ballo, Sekou Bah, Estelle NH Youl
Objective: The aim of this study was to evaluate the hepatoprotective effect of the combination
Methods: Serum liver markers, tissue antioxidant activity, and histological changes in the livers of rats from the blank, negative (distilled water), positive (silymarin 100 mg/kg bw), and test (combination 500 mg/kg bw) groups were measured after(...)
Antioxidant, Hepatoprotective, Ximenia americana, Terminalia macroptera, Combination$
ARTICLE
Acute toxicity and anti-inflammatory activity of an improved traditional medicine developed in Burkina Faso
Mohamed Bonewendé BELEMLILGA1,3*, Tata Kadiatou TRAORE1, Gilchrist Abdoul Laurent BOLY1, Séripouguin Rihanata BOURGOU1,2, Ladji TRAORE1,2, Salfo OUEDRAOGO1, Jean Claude R. P. OUEDRAOGO1, Sylvain ILBOUDO1,3, Moussa OUEDRAOGO2, Dieudonné KINDA 2, Félix B. KINI1, Aristide TRAORE1, Noufou OUEDRAOGO1,3
practitioners in Burkina Faso as used for hepatoprotective and hepatocurative treatment for viral hepatitis B. The study's main objective was to investigate the anti-inflammatory properties of this ITM, which is used in treating viral hepatitis B in traditional medicine in Burkina Faso. Phytochemical screening revealed the presence of flavonoi(...)
ITM, Phytochemical, Acute toxicity, Anti-inflammatory, Antioxidants
ARTICLE
Pharmaceutical approaches for enhancing solubility and oral bioavailability of poorly soluble drugs
Isaïe Nyamba , Charles B Sombié, Moussa Yabré , Hermine Zimé-Diawara , Josias Yaméogo , Salfo Ouedraogo , Anna Lechanteur, Rasmané Semdé , Brigitte Evrard
High solubility in water and physiological fluids is an indispensable requirement for the pharmacological efficacy of an active pharmaceutical ingredient. Indeed, it is well established that pharmaceutical substances exhibiting limited solubility in water are inclined towards diminished and inconsistent absorption following oral administration(...)
Formulation, Solubility, Dissolution rate, Bioavailability
COMMUNICATION
Advancing Interprofessional Education in Pharmacy in French-speaking countries: Insights from CIDpharmef Survey
BARDET J-Didier; SCHNEIDER Marie P; KAUFMANN Béatrice; FLORA Luigi; STANDAERT Annie; YOUL Estelle NH; JANOLY-DUMENIL Audrey; VANIER Marie-Claude
The aim of this study was to Identify which Faculties of Pharmacy in the network have implemented IPE training activities and draw up a portrait of these IPE training courses, of the teaching resources and of the expertise available
In 2023, a survey was sent to deans of the 62 Faculties of Pharmacy to identify those offering IPE and map ava(...)
Interprofessional Education, Pharmacy, French-speaking countries, CIDpharmef
ARTICLE
Quality Characteristics and Thermal Behavior Diversity of Traditional Crude Shea (Vitellaria paradoxa Gaertn) Butter from Burkina Faso
Bertrand W. F. Goumbri, Alfred Kouakou Kouassi, Roland Marini Djang’eing’a, Rasmané Semdé, Ange Mouithys-Mickalad, Abdoul Karim Sakira, Gérard B. Josias Yaméogo, Touridomon Issa Somé, Sabine Danthine
The aim of this study was to establish a comparative analysis of the physicochemical and the thermal behavior by p-NMR for solid fat content (SFC), and differential scanning calorimetry (DSC) of shea butter (SB) from Burkina Faso, related to different traditional extraction processes. Thirty-seven samples obtained from different localities wer(...)
Shea butter, Extraction process, Solid fat content, Differential scanning calorimetry, Chemical quality, Burkina Faso
ARTICLE
Evaluation of the Med Safety mobile app for reporting adverse events in Burkina Faso
Joël Ouoba, Sougrimani Haro‑Lankoandé, Aminata P. Nacoulma, Corinne Simone, Collette Merle, Branwen Johanna Hennig , Souleymane Fofana, Lassané Kaboré, Emile Ouédraogo, Ruth Sawadogo, Sekou Samadoulougou, Fati Kirakoya‑Samadoulougou
Introduction Smartphone applications (apps) for pharmacovigilance present an opportunity for integration as cost-efective
healthcare service intervention into basic healthcare services in low-resource settings. This study aimed to (i) evaluate the
implementation of the Med Safety app in Burkina Faso, and (ii) compare the characteristics of t(...)
Med Safety, reporting adverse events
ARTICLE
Essai de formulation de suppositoires à base d’extraits aqueux des écorces de tronc de Parkia biglobosa jacq. (Fabaceae-Mimosoideae) pour la prise en charge de l’inflammation due à la crise hémorroïdaire
Boladé Constantin ATCHADE, Salfo OUEDRAOGO, Kadiatou Tata TRAORE, Josias B. G YAMEOGO, Charles B. SOMBIE, Hermine ZIME/DIAWARA, Rasmané SEMDE
La maladie hémorroïdaire est un état pathologique caractérisé par une dilatation de la veine recto-anale plexus. Une enquête ethnobotanique a révélé l’utilisation des écorces de tronc de Parkia biglobosa (Jacq.) sous forme de pommade ou décoction en lavement anal pour son traitement. L’objectif de cette étude était de caractériser l’extrait af(...)
Parkia biglobosa, Suppositoires, Activité antioxydante et anti-inflammatoire