Publications (489)
ARTICLE
Plasma lipid profile including the high density lipoprotein (HDL) subclasses in hypertensive patients in Ouagadougou, Burkina Faso
Alice T. C. R. Kiba Koumaré, Absetou Guira, André Samandoulougou, Elie Kabré, Issaka Sondé, Talkmore Maruta, Jacques Simporé, Jean Sakandé
The study was undertaken to evaluate the interest of cholesterol subclasses in the management of hypertensive patients recruited at University Hospital Yalgado Ouedraogo of Ouagadougou (Burkina Faso, West Africa). The distribution of hypertensive was reported as 45 (35.4%) without complications, 42 (33%) with cardiovascular complications and 4(...)
words: Lipids profile, HDL subclasses, hypertensive.
ARTICLE
Hemoglobin S and C affect protein export in Plasmodium falciparum-infected erythrocytes
Nicole Kilian, Sirikamol Srismith, Martin Dittmer, Djeneba Ouermi, Cyrille Bisseye, Jacques Simporé, Marek Cyrklaff, Cecilia P Sanchez, Michael Lanzer
Malaria is a potentially deadly disease. However, not every infected person develops severe symptoms. Some people are protected by naturally occurring mechanisms that frequently involve inheritable modifications in their hemoglobin. The best studied protective hemoglobins are the sickle cell hemoglobin (HbS) and hemoglobin C (HbC) which both r(...)
Hemoglobinopathy ; Malaria ; P. falciparum ; Protein export
ARTICLE
Evaluation of a PfHRP-2 based rapid diagnostic test versus microscopy method among HIV-positive and unknown serology patients in Ouagadougou, Burkina Faso
Arianna Andreoli, Pier Francesco Giorgetti, Virginio Pietra, Alessia Melzani, Wetien Seni, Francesco Castelli, Jacques Simporé
We evaluated the performance of a malaria rapid diagnostic test (RDT; Malaria Quick Test(®); Cypress Diagnostic) compared with the standard thick-smear microscopy method using blood samples from human immunodeficiency virus (HIV)-infected individuals and individuals of unknown HIV status collected in Ouagadougou, Burkina Faso. Our results show(...)
PfHRP-2 ; Rapid diagnostic test ; Malaria ; HIV ; Burkina Faso ; Sensitivity ; Specificity ; Microscopy
ARTICLE
Reference ranges of cholesterol sub-fractions in random healthy adults in Ouagadougou, Burkina Faso
Alice T C R Kiba Koumaré, Linda P L Sakandé, Elie Kabré, Issaka Sondé, Jacques Simporé, Jean Sakandé
In Burkina Faso, the values that serve as clinical chemistry reference ranges are those provided by European manufacturers' insert sheets based on reference of the Western population. However, studies conducted so far in some African countries reported significant differences in normal laboratory ranges compared with those of the industrialize(...)
Cholesterol sub-fractions, reference ranges, cardiovascular risk, Burkina Faso, HDL2, HDL3, LDL cholesterol
ARTICLE
The antimalarial action of aqueous and hydro alcoholic extracts of Artemisia annua L. cultivated in Benin: In vitro and in vivo studies.
Hermine Zime-Diawara, Habib Ganfon, Fernand Gbaguidi, Achille Yemoa, Joanne Bero, Olivia Jansen, Brigitte Evrard, Mansourou Moudachirou, Michel Frederich and Joëlle Quetin-Leclercq
The aqueous and hydro alcoholic extracts of Artemisia annua plants acclimatized and set in culture in Benin, were
investigated for their in vitro and in vivo antimalarial value. These extracts were prepared by decoction and
maceration using water and ethanol, and were tested for in vitro activity against the strains of Plasmodium
falciparum(...)
Artemisia annua extracts, in vitro studies, in vivo studies, artemisinin potentiation
ARTICLE
Seroprevalence of latent Toxoplasma gondii infection among HIV-infected pregnant women in Bobo-Dioulasso, Burkina Faso
S. Bamba, Y. Sourabié, T. R. Guiguemdé, D. S. Karou, J. Simporé, M. Bambara, I. Villena
The deficit of cellular immunity, as found in HIV infected individuals, may lead to the reactivation of latent Toxoplasma gondii cysts, with as consequence, the occurrence of toxoplasmosis and an eventual vertical transmission of the disease during pregnancy. The present study was designed for determining the occurrence of latent Toxoplasma go(...)
Toxoplasma gondii ; VIH ; femmes enceintes ; séroprévalence ; infection latente ; Burkina Faso ; transmission verticale ; immunodéficience
ARTICLE
A decade of follow-up and therapeutic drug monitoring in HIV-2 immunocompromised patients at St Camille and General Lamizana Military Medical Centers, Burkina Faso, West Africa
M. Sanou, S. T. Soubeiga, F. Bationo, T. R. Compaore, T. M. Zohoncon, G. N. Diatto, P. Ouedraogo, V. Pietra, B. M. Nagalo, C. Bisseye, R. Ouedraogo Traore, J. Simporé
Although, HIV-2 is generally less pathogenic than HIV-1 and its progression towards AIDS occurs less frequently. HIV-2 remains an important cause of disease in West Africa. This study aimed to evaluate HIV-1 and HIV-2 prevalence among pregnant women and to describe the demographic and clinical profile of patients with HIV-2 infection from 2003(...)
HIV-2 ; VIH ; traitement antirétroviral ; suivi thérapeutique ; ouest africain ; Burkina Faso ; CD4 ; patients immunodéprimés ; centres médicaux ; infections opportunistes
ARTICLE
Department of Biochemistry /Microbiology/Molecular Biology, Biomolecular Research Centre Pietro Annigoni (CERBA)/LABIOGENE, University of Ouagadougou, Ouagadougou, Burkina Faso Saint Thomas D’Aquin University (USTA), Ouagadougou, Burkina Faso
Jacques Simpore
Human immunodeficiency virus infection/acquired immunodeficiency syndrome (HIV/AIDS) is a
public health issue worldwide because of its high prevalence, its pathogenic character, its mortality,
and its morbidity. AIDS is a particular disease which entirely affects the infected person: his/her
physical appearance, mental, morale, close relati(...)
HIV/AIDS; Prevention; Screening; Ethics; Discrimination; Medical care; Antiretroviral drugs
ARTICLE
What lies behind gender inequalities in HIV/AIDS in sub-Saharan African countries: Evidence from Kenya, Lesotho and Tanzania
Drissa Sia, Yentéma Onadja, Arijit Nandi, Anne Foro, Timothy Brewer
Within sub-Saharan Africa, women are disproportionately at risk for acquiring and having human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS). It is important to clarify whether gender inequalities in HIV
prevalence in this region are explained by differences in the distributions of HIV risk factors, differences in the(...)
Mots clés non renseignés
ARTICLE
A variant of DC-SIGN gene promoter associated with resistance to HIV-1 in serodiscordant couples in Burkina Faso
Thérèse Samdapawindé Kagoné, Cyrille Bisseye, Nicolas Méda, Jean Testa, Virginio Pietra, Dramane Kania, Albert Théophane Yonli, Tegwindé Rebeca Compaoré, Jean Baptiste Nikiéma, Comlan de Souza, Jacques Simpore
Objective: To study the involvement of variations in 4 genes associated with susceptibility and/or protection against HIV-1 in serodiscordant couples in Burkina Faso, namely, genes encoding HLA-B57, interferon regulatory factor 1 (IRF1), dendritic cell-specific ICAM3-grabbing nonintegrin (DC-SIGN) and CCR5 delta 32 (CCR5Δ32).
Methods: Two D(...)
Burkina Faso; Genetic resistance; HIV-1
ARTICLE
Protocol for the process evaluation of interventions combining performance-based financing with health equity in Burkina Faso
Valéry Ridde, Anne-Marie Turcotte-Tremblay, Aurélia Souares, Julia Lohmann, David Zombré, Jean Louis Koulidiati, Maurice Yaogo, Hervé Hien, Matthew Hunt, Sylvie Zongo and Manuela De Allegri
Background The low quality of healthcare and the presence of user fees in Burkina Faso contribute to low utilization of healthcare and elevated levels of mortality. To improve access to high-quality healthcare and equity, national authorities are testing different intervention arms that combine performance-based financing with community-based(...)
Performance-based financing, Community-based health insurance, User fee exemption, Equity, Burkina Faso, Implementation study, Process evaluation, Case study methodology, Research protocol
ARTICLE
Assessment of the Prevalence of Extended-Spectrum Beta Lactamase Producing Gram-Negative Bacilli at the Cdg-Chup, Ouagadougou
Sanou M, Ky/Ba A, Coulibali P, Nagalo M, Ouedraogo S, Tamboura M, Kambire D, Bisseye C, Bakiono F, Simpore J, Ouedraogo R
Introduction
The bacterial resistance to antibiotics is becoming a serious concern in developing countries due to precarious hygiene conditions, inappropriate prescription as well as self-medication and free sale of antibiotics.
The general objective of this study is to assess the prevalence of strains producing ESBL in the BGN isolated(...)
ESBL, enterobacteria, gram-negative bacilli, hospitalised, out-patients
ARTICLE
New astrovirus in human feces from Burkina Faso
Tung Gia Phan, Johan Nordgren, Djeneba Ouermi, Jacques Simpore, Leon W Nitiema, Xutao Deng, Eric Delwart
Background: A significant fraction of cases of diarrhea, a leading cause of childhood mortality worldwide, remain unexplained.
Objectives: To identify viruses in unexplained cases of diarrhea using an unbiased metagenomics approach.
Study design: Viral nucleic acids were enriched from the feces from 48 cases of unexplained diarrhea from(...)
Astrovirus ; Children ; Diarrhea ; Metagenomics ; Species
ARTICLE
Clinical and immunological outcomes according to adherence to first-line HAART in a urban and rural cohort of HIV-infected patients in Burkina Faso, West Africa
Emanuele Focà, Silvia Odolini, Giorgia Sulis, Stefano Calza, Virginio Pietra, Paola Rodari, Pier Francesco Giorgetti, Alice Noris, Paul Ouedraogo, Jacques Simpore, Salvatore Pignatelli, Francesco Castelli
Background: Aim of our study is to investigate the clinical and immunological outcomes according to first-line HAART adherence in a large cohort of HIV-infected patients in Burkina Faso.
Methods: A retrospective study was conducted between 2001 and 2009 among patients from two urban medical centers [St. Camille Medical Center (CMSC) and "Pi(...)
Burkina Faso ; HAART ; Adhérence au traitement ; VIH ; CD4 ; Cohorte urbaine et rurale ; Suivi clinique ; Immunologie
ARTICLE
Contrôle de qualité des jus d’ananas produits au Bénin et commercialisés à Cotonou
A.Yemoa, H. Ganfon, H. Zimé, M. Sallan, R. Osséni, T. Hountohotègbè, A. Bigot, J. Hounhouigan
La consommation de jus d'ananas a connu une forte augmentation ces dernières années au Bénin. Le
contrôle de qualité (QC) de dix marques de jus d'ananas sélectionnées à partir d'une trentaine recensée
sur les marchés de Cotonou a porté sur la détermination de différents paramètres physico chimiques
et microbiologiques.
De l'analyse physiqu(...)
jus d'ananas, Contrôle de Qualité, Bénin.