Publications (416)
ARTICLE
[Evolution of antibiotic-resistance Staphylococcus aureus in Saint Camille Medical Centre in Ouagadougou]
Simplice D Karou, M C W Nadembega, B Zeba, D P Ilboudo, D Ouermi, S Pignatelli, V Pietra, M Gbeassor, C De Souza, Jacques Simpore
Background: Monitoring the antibiotic resistance of microorganisms in a specific geographic area can be useful in developing new approaches to first-intention antibiotherapy.
Objective: The purpose of this study was to describe the evolution of resistance of Staphylococcus aureus to antibiotics routinely used at Saint Camille Medical Centre(...)
Staphylococcus aureus, résistance aux antibiotiques, beta-lactamines, antibiogramme, Ouagadougou, Burkina Faso
ARTICLE
Genetic variation in human HBB is associated with Plasmodium falciparum transmission
Gouagna LC, Bancone G, Yao F, Yameogo B, Dabiré KR, Costantini C, Simpore J , Ouedraogo JB, Modiano D.
Genetic factors are known to have a role in determining susceptibility to infectious diseases 1, 2, although it is unclear whether they may also influence host efficiency in transmitting pathogens. We examine variants in HBB that have been shown to be protective against malaria 3 and test whether these are associated with the transmission of t(...)
HBB, Plasmodium
ARTICLE
Incidence of tuberculosis after HAART initiation in a cohort of HIV-positive patients in Burkina Faso
M. Dembélé, N. Saleri, A.C.C. Carvalho, T. Saouadogo, A.D. Hien, I. Zabsonre, S.T. Koala, J. Simporé, A. Matteelli
Objective: To determine the incidence rates of tuberculosis (TB) after the initiation of highly active antiretroviral treatment (HAART).
Methods: We conducted a retrospective cohort study on four human immunodeficiency virus (HIV) treatment centres in Ouagadougou, Burkina Faso. TB incidence was measured at different intervals after HAART in(...)
Tuberculose, VIH, HAART, incidence, Burkina Faso, CD4, IMC, épidémiologie, soins cliniques
ARTICLE
Antiretroviral (ARV) Therapy in Resource Poor Countries: What do we Need in Real Life?
Francesco Castelli, Virginio Pietra, Ismael Diallo, Richard F. Schumacher, Jacques Simporé
Significant progresses have been made in the last 5 years towards the ultimate goal to provide universal access to care for all HIV/AIDS patients needing antiretroviral treatment in resource-poor countries. However, many barriers are still to be overcome, including () cost of care for the individual, () stigma, () lack of qualified human resou(...)
ARV, VIH, accès aux soins, pays en développement, obstacles, infrastructures, pédiatrie, ruralité, formation, prévention, politique de santé, médicaments de 3e ligne
ARTICLE
Isolation of a tannic acid-degrading Streptococcus sp. from an anaerobic shea cake digester
L.W. Nitiema, D. Dianou, J. Simporé, S.D. Karou, P.W. Savadogo, A.S. Traoré
An anaerobic digester fed with shea cake rich in tannins and phenolic compounds rich-shea cake and previously inoculated with anaerobic sludge from the pit of a slaughterhouse, enabled six months acclimatization of the bacteria to aromatic compounds. Afterwards, digester waste water samples were subject to successive culture on media with 1 g(...)
Tannic acid, Streptococcus, digestion anaérobie, shea cake, gallic acid, bactéries dégradant les tanins, phénoliques, fermentation, bioconversion, pH optimal, microbiologie environnementale
ARTICLE
Stratégie d’utilisation des substances naturelles dans la prise en charge des personnes vivant avec le VIH : expérience du Burkina Faso
J. B. Nikiéma, K. Djierro, J. Simporé et al.
Au Burkina Faso, les personnes vivant avec le VIH (PvVIH) ont régulièrement recours à des substances naturelles pour traiter certaines infections opportunistes. C’est ainsi que le suc des feuilles fraîches de Mitracarpus scaber Zucc. ex Schult. & Schult. f. (Rubiaceae) et de Senna alata (L.) Roxb. (Fabaceae) sont utilisés comme antimycosiques.(...)
VIH, Burkina Faso, traitement antirétroviral, plantes médicinales, médecine naturelle, médicaments
ARTICLE
Aetiology of Acute Gastro-Enteritis in Children at Saint Camille Medical Centre, Ouagadougou, Burkina Faso
J. Simpore, D. Ouermi, D. Ilboudo, A. Kabre, B. Zeba, V. Pietra, S. Pignatelli, J.B. Nikiema, G.B. Kabre, S. Caligaris, F. Schumacher, F. Castelli
The present study aims at identifying the infectious agents responsible for child Acute Gastro-Enteritis (AGE) in Ouagadougou. From May 5 2006 to June 22 2008, 648 children aged from 2 to 41 months, with at least an average of 3 loose stools per day have been enrolled for coproculture, parasitology and virology test. Among them, 34 (5.25%) wer(...)
salmonella, E. coli, EPEC, Giardia intestinalis, rotavirus, diarrhoea, acute gastro-enteritis
ARTICLE
Medicinal plants used in traditional medicine in the centre east region of Burkina Faso
J.M.K. Ky, P. Zerbo, C. Gnoula, J. Simporé, J.B. Nikiema, J. Millogo-Rasolodimby
The present research focused on the inventory and the use of plants in traditional medicine for the treatment of diseases in this area. The method was based on ethnobotanical surveys with semi-directing interview, conducted from November 2006 to December 2007 among a sample of 50 people aged between 40 and 80 years and very experienced in trad(...)
Plantes médicinales, médecine traditionnelle, ethnobotanique, Burkina Faso, maladies gastro-intestinales, paludisme, pharmacopée vétérinaire, ressources génétiques végétales
ARTICLE
Epidemiology and prognostic factors for sickle cell retinopathy in Ouagadougou (Burkina Faso)
J.W. Diallo, O. Sanfo, I. Blot, N. Meda, P. Sawadogo, A. Ouedraogo, J. Simporé
Introduction: The frequency of sickle cell disease varies from 5% to 20% in Africa.
Patients and method: This retrospective study investigated 173 patients in an ambulatory setting from August 2000 to July 2006. The study included 98 women and 75 men, aged 15-62 years, with a mean age of 26.7 years.
Results: Only 89 patients (71 SC and 1(...)
rétinopathie drépanocytaire, facteurs pronostiques, épidémiologie, Ouagadougou, Burkina Faso
ARTICLE
Antimicrobial resistance and serotype distribution of Streptococcus pneumoniae strains causing childhood infection in Burkina Faso
Leonard C. Bere, Jacques Simpore, Simplice D. Karou, Boukaré Zeba, Augustin P. Bere, Elizabeth Bannerman, Jacques Bille, Mireille Dosso
In Burkina Faso, a Western African country, reports on pneumococci carriage, resistance patterns and serotypes are inconsistent. The present study was conducted in order to evaluate these parameters. Thus 860 nasopharyngeal swabs were collected from children attending vaccination centers for pneumococci isolation, identification and serotype d(...)
Streptococcus pneumoniae, résistance antimicrobienne, sérotypes, enfants, Burkina Faso, antibiotiques
ARTICLE
Reversible reduction of nevirapine plasma concentrations during rifampicin treatment in patients coinfected with HIV-1 and tuberculosis
Alberto Matteelli, Nuccia Saleri, Paola Villani, Victor Bonkoungou, Anna Cristina C Carvalho, Seni Kouanda, Marie J Sanou, Jacques Simporé, Laura Monno, Giampiero Carosi, Mario Regazzi, Mathurin Dembele
Background: Nevirapine (NVP) plasma levels are reduced in patients receiving rifampicin (RFM) for tuberculosis (TB) treatment. We determined variations over time of the pharmacokinetic parameters of NVP in patients who receive RFM.
Methods: HIV-1-infected patients with CD4+ T-lymphocyte count <or=100 cells per microliter and TB diagnosis re(...)
nevirapine, rifampicin, pharmacokinetics, HIV-1, tuberculosis, plasma concentrations, AUC, combined therapy
ARTICLE
Co-infection of Toxoplasma gondii with HBV in HIV-infected and uninfected pregnant women in Burkina Faso
D. Ouermi, J. Simpore, A. M. G. Belem, D. S. Sanou, D. S. Karou, D. Ilboudo, C. Bisseye, S. M. Onadja, V. Pietra, S. Pignatelli, C. Gnoula, J. B. Nikiema, G. B. Kabre
Toxoplasma gondii infections can induce serious complications in HIV-infected pregnant women, leading to miscarriage; favour the mother-to-child transmission of HBV and HIV and birth defects. The purposes of this study were: (1) to quantify IgM and IgG antibodies to Toxoplasma gondii in HIV-seropositive and seronegative pregnant women, (2) to(...)
Toxoplasma gondii, co-infection, hépatite B, VIH, grossesse, Burkina Faso, anticorps IgM/IgG, HBsAg, femmes enceintes
ARTICLE
IND-6, a highly divergent IND-type metallo-beta-lactamase from Chryseobacterium indologenes strain 597 isolated in Burkina Faso
Boukaré Zeba, Filomena De Luca, Alain Dubus, Michael Delmarcelle, Jacques Simporé, Odile G. Nacoulma, Gian Maria Rossolini, Jean-Marie Frère, Jean-Denis Docquier
The genus Chryseobacterium and other genera belonging to the family Flavobacteriaceae include organisms that can behave as human pathogens and are known to cause different kinds of infections. Several species of Flavobacteriaceae, including Chryseobacterium indologenes, are naturally resistant to beta-lactam antibiotics (including carbapenems)(...)
Chryseobacterium indologenes, Burkina Faso, IND-6, metallo-beta-lactamase, résistance aux antibiotiques, beta-lactamines, ceftazidime, cefepime, aminoglycosides
ARTICLE
Mother-to-child HIV and HHV-8 transmission in neonates at Saint Camille Medical Centre in Burkina Faso
D. Ilboudo, J. Simpore, D. S. Sanou, D. Karou, D. J. Sia, D. Ouermi, C. Bisseye, T. Sagna, S. Odolini, F. Buelli, V. Pietra, S. Pignatelli, C. Gnoula, J. B. Nikiema, F. Castelli
In Sub-Saharan Africa, many HIV infected people are co-infected with Human Herpes Virus 8 (HHV-8). Therefore, the present study aimed to: (1) identify the pregnant women co-infected by HIV and HHV-8 at Saint Camille Medical Centre; (2) use three molecules (Zidovudine, Nevirapine and Lamivudine) to interrupt the vertical transmission of HIV and(...)
Transmission mère-enfant, VIH, HHV-8, antirétroviraux, PCR, néonatologie, Burkina Faso
ARTICLE
HIV NOTIFICATION TO THE PARTNER AMONG PUERPERAS IN SUB-SAHARAN AFRICA
L. R. Tomasoni, M. Galli, V. Vullo, S. Declich, M. Giuliano, V. Pietra, M. Fabiani, J. Simpore, E. Gianelli, S. Rusconi, A. Riva, G. Guaraldi, K. Luzi, G. Russo, M. Lichtner, F. Castelli
HIV serostatus disclosure to sexual partner may lead to clear public health benefits (motivation for partner testing, behavior changes, earlier access to medical care), but it may also lead to women rejection, loss of economic support, physical and emotional abuse. Studies from developing countries suggest that a larger proportion of women com(...)
HIV disclosure, partner notification, puerperas, Sub‑Saharan Africa, public health, stigma, gender dynamics