Publications (375)
ARTICLE
Prevalence of hepatitis virus delta infection among HBVAgs positive blood donors at the Regional Blood Transfusion Center of Ouagadougou, Burkina Faso
Moutanou Modeste Judes ZEYE, Serge Potiandi DIAGBOUGA, Florencia Wendkuuni DJIGMA, Mahamoudou SANOU, Dorcas Obiri-Yeboah, Serge Yannick OUEDRAOGO, Abel Pegdwendé SORGHO, Abdoul Karim OUATTARA, Arsène Wendpagnangdé ZONGO, Abdoulaye TANGARA, Tegwindé Rébéca COMPAORE, Siaka OUATTARA, Jacques SIMPORE
Background: Infection with hepatitis viruses constitutes a public health problem in Burkina Faso.
Several previous studies have estimated the prevalence of viral hepatitis A, B and C. This study aimed
to study the prevalence of hepatitis delta infection in apparent healthy blood donors positive for the
antigen of hepatitis B virus.
Methods(...)
HBV, HDV, Real Time PCR, Blood donors, Ouagadougou, Burkina Faso.
ARTICLE
Activité antiplasmodiale des plantes médicinales d’Afrique de l’Ouest: Revue de la littérature
Kodjovi AGBODEKA, Holaly E. Gbekley, Simplice D. KAROU, Kokou ANANI, Jacques Simpore
Le paludisme reste un problème majeur de santé publique dans la zone intertropicale. En raison du problème de plus en plus croissant de la résistance du Plasmodium aux antipaludiques classiques, il y a urgence de découvertes de nouvelles molécules. Historiquement, la majorité de ces médicaments est synthétisée à partir de plantes médicinales o(...)
Ethnomedecine, Plasmodium, antipaludique, Indice de sélectivité, Croton labatus.
ARTICLE
Evaluation of a Real-Time Polymerase Chain Reaction for the Laboratory Diagnosis of Giardia intestinalis in Stool Samples from Schoolchildren from the Centre-Ouest and Plateau Central Regions of Burkina Faso
Serge Diagbouga, Tibila Kientega, Séverine Erismann, Djeneba Ouermi, Jasmina Saric, Peter Odermatt, Tegwinde R. Compaore, Arsene Zongo, Grissoum Tarnagda, Boubacar Savadogo, Jürg Utzinger, Guéladio Cisse, Jacques Simpore
Objective: Giardiasis, a zoonotic, diarrhoeal disease with worldwide occurrence, is routinely diagnosed by
microscopic examination of stool samples. However, implementation of this method relies on skilled personal, it is
time consuming and relatively low in sensitivity. A superior diagnostic approach to detect the causative agent Giardia
i(...)
Giardia intestinalis; Molecular diagnosis; Stool; Burkina Faso
ARTICLE
Incompatible blood transfusion in children in Burkina Faso
Eléonore Kafando, Lady Rosny Wandji Nana, Yacouba Domo, Yacouba Nébié, Dorcas Obiri-Yeboah, Jacques Simporé
Background: Transfusion therapy saves lives, but remains complicated by RBC immunization. So, erythrocyte phenotyping in blood donors and recipients is crucial in minimizing alloimmunization. Objectives: To determine the frequency of Rhesus and Kell incompatible red blood cell transfusions in children. Methods: A cross-sectional observationa(...)
incompatible blood, alloimmunization, red blood cell, children
ARTICLE
Improving blood transfusion safety: a survey on the knowledge and attitudes of health professionals in blood transfusion at the yalgado ouedraogo university hospital center, Burkina Faso
Kafando Eleonore, Koumare AR, Sawadogo S, Nebie Y, Tinto A, Simpore J
Introduction: National guidelines for best transfusion practices have been disseminated so that their recommendations can be applied to any health facility. This work was part of the approach to promoting transfusion safety. Its objective was to study the knowledge and attitudes of the clinical healthcare professionals in the Yalgado Ouédraogo(...)
Blood transfusion, Knowledge, Attitudes, Health professionals, Burkina Faso
ARTICLE
First ĞƚĞcƟŽŶ of Resistance Genes Encoding Extended Spectrum β-Lactamase Producing Escherichia coli at Lomé, Togo
Fortune D Salah, Serge Diagbouga, Amana Metuor Dabire, Adodo Y Sadji, Christelle Nadembega, Aissatou Moumouni, Serge Théophile Soubeiga, Abdoul Karim Ouattara, Theodora Zohoncon, Abiba Banla Kere, Simplice Karou, Jacques Simpore
Background: Extended Spectrum β-lactamases (ESBLs) are
enzymes produced by some bacteria that ŝnĂcƟvĂƚĞ
oxyimino-cephalosporins, a class of β-lactam ĂnƟbŝŽƟcƐ
family. They are mainly encoded by the β-lactamase gene
families TEM, SHV and CTX-M. The Enterobacteriaceae
expressing these genes, in ƉĂrƟcƵůĂr Escherichia coli are
widely expande(...)
E. coli, ESBL, blaTEM, blaSHV, blaCTX-M1, Togo
ARTICLE
What explains gender inequalities in HIV/AIDS prevalence in sub-Saharan Africa? Evidence from the Demographic and Health Surveys
Drissa Sia, Yentéma Onadja, Mohammad Hajizadeh, S. Jody Heymann, Timothy F. Brewer, Arijit Nandi
Background: Women are disproportionally affected by human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) in sub-Saharan Africa (SSA). The determinants of gender inequality in HIV/AIDS may vary across countries and require country-specific interventions to address them. This study aimed to identify the socio-demographic(...)
Mots clés non renseignés
ARTICLE
Prevalence of non-adherence to highly active antiretroviral therapy and its related clinical and therapeutic factors in Ouagadougou (Burkina Faso)
O. Guira, D. S. R. Kaboré, G. Dao, N. Zagré, T. M. Zohoncon, V. Pietra, J. Simporé
Introduction : Non-adherence to highly active antiretroviral therapy is deleterious in HIV/AIDS programs. This study contributes to the identification of its frequency and of the clinical and therapeutic factors that determine it. Material and methods : This cross-sectional study took place from December 15, 2013, to February 18, 2014, at the(...)
ARV ; Burkina Faso ; VIH/SIDA ; non-observance thérapeutique
ARTICLE
Detection of High Prevalence of TEM/SHV/CTX-M Genes in ESBL Producing and Multidrug Resistant Klebsiella pneumoniae and Klebsiella oxytoca
Diagbouga S, Salah F D, Sadji A Y, Dabire A M, Nadembega C, Kere A B, Soubeiga S T, Ouattara A K, Zohoncon T, Belemgnegre M, Karou S, Simpore J
Background: Klebsiella spp. are Enterobacteriaceae frequently isolated from pathological specimens during
urinary tract infections, bloodstream infection, and pus. They are becoming more and more resistant to antibiotics
and challenging treatment options. β-lactamases are a great variety of enzymes capable of inducing resistance to βlactams.(...)
Klebsiella spp; Antimicrobial resistance; ESBL; TEM; SHV; CTX-M; Togo
ARTICLE
Distribution of High-Risk Human Papillomavirus Genotypes in Precancerous Cervical Lesions in Ouagadougou, Burkina Faso
Diagbouga S, Salah FD, Sadji AY, Dabire AM, Nadembega C, Kere AB, Soubeiga ST, Ouattara AK, Zohoncon T, Belemgnegre M, Karou S, Simpore J
Aims: We aimed at identifying the high-risk HPV genotypes associated with high-grade dysplastic cervical lesions in Burkina Faso. The available vaccines to Burkina Faso only protect against two high risk HPV genotypes: HPV 16 and 18. Are the genotypes identified in the high-grade precan-cerous lesions in this survey covered by the available va(...)
HPV, Cancer, CIN, Cervix, Burkina Faso
ARTICLE
ANTIPLASMODIAL AND DPPH RADICAL SCAVENGING EFFECTS IN EXTRACTS FROM ACACIA MACROSTACHYA (MIMOSACEAE) DC
Tondé Issa, Fofana Souleymane, Gnoula Charlemagne, Palé Eloi, Nébié Roger HC, Nikiema Jean Baptiste, Simpore Jacques, Guissou Innocent Pierre
Background: Acacia macrostachya is a medicinal plant used in the
traditional treatment of snakebites and pathologies accompanied with
oxidative stress such as malaria, inflammation, and painful spasms.
Objective: The purpose is to study the antioxidant and antiplasmodial
effects in extracts of leaves and bark of twigs from Acacia
macrosta(...)
A. machrostachya, antioxidant, antiplasmodial, Burkina Faso.
ARTICLE
Comparative Effects of Light and Water Stresses on Antioxidant Enzymes Activity of Three Ecotypes of Jatropha curcas Seedlings
Razacswendé Fanta Ouédraogo, Charlemagne Gnoula, Simplice Damintoti Karou, Gérard Zombré, Jacques Simporé
Jatropha curcas is a Euphorbiaceae whose seed lipids attract biofuel industry attention. However, the effects of environmental stressors inducing resistance mechanisms and affecting the seed yield of the plant are very little investigated. In this study, we evaluated the effect of water stress and sunlight luminosity on the antioxidant enzymes(...)
Jatropha curcas, seedlings, water deficit, sunlight, soluble proteins, antioxidant enzymes, proline
ARTICLE
DPPH radical scavenging and lipoxygenase inhibitory effects in extracts from Erythrina senegalensis (Fabaceae) DC
Fofana Souleymane, Gnoula Charlemagne, Ouédraogo Moussa, Palé Eloi, Nébié Roger HC, Nikiema Jean Baptiste, Guissou Innocent Pierre, Simpore Jacques
Erythrina senegalensis DC (Fabaceae) is a plant used in traditional medicine in Burkina Faso (West Africa) to cure several diseases such as malaria, rheumatism, abdominal pain, fibroma and infections which are always accompanied by oxidative stress. This study aimed to highlight the antioxidant activities in dichloromethane (DCM) and ethyl ace(...)
E. senegalensis, antioxidant, 12-lipoxygenase I-B inhibitory.
ARTICLE
Microbiological and kinetic detection of gram negative bacilli producing extended-spectrum- β-lactamases (esbl) in emergencies and reanimation units of university hospital center, Yalgadoouedraogo, Burkina Faso
K.J. Zongo, A. Metuor Dabiré, B. Kabore, I. Sanou, L. Sangaré, J. Simporé, B. Zeba
Background: Epidemiology of extended-Spectrum- β-lactamases has become worldwide, and our aim was to establish the prevalence of isolates producer in university hospital center Yalgado OUEDRAOGO particularly in reanimation and emergencies units.
Material and methods: Prospective study was drive during July 2009 to march 2012 in order to col(...)
microbial and kinetic analysis, Gram negative bacilli, extended-Spectrum- β-lactamase, emergencies, reanimation
ARTICLE
First detection of bla TEM, SHV and CTX-M among Gram negative bacilli exhibiting extended spectrum β- lactamase phenotype isolated at University Hospital Center, Yalgado Ouedraogo, Ouagadougou, Burkina Faso
KJ Zongo, AM Dabire, LG Compaore, I Sanou, L Sangare, J Simpore, B Zeba
Resistance to a wide variety of common antimicrobials is observed among clinical strains designed as extended spectrum β-lactmase (ESBL) producers. They produce enzymatic protein which inactivates efficiently oxyimino cephalosporin and constitutes a serious global health concern that has complicated treatment strategies. Many studies report h(...)
Extended spectrum β-lactamase (ESBL), double disk synergy test, blaTEM, blaSHV, blaCTX-M, PCR