Publications (375)
ARTICLE
Ethnobotanical survey of medicinal plants used in the management of hypertension in the Maritime region of Togo
Holaly E. Gbekley, Simplice D. Karou, Gnatoulma Katawa, Tchadjobo Tchacondo, Komlan Batawila, Yaovi Ameyapoh, Jacques Simporé
Background: Hypertension is one of the most common chronic diseases in modern societies and there is evidence that its incidence and severity are increasing. This survey was conducted to investigate the plants used by the Togolese traditional healers to treat the disease.
Method: From January to June 2016, an ethnobotanical survey was conduct(...)
Hypertension, traditional medicine, ethnobotanical survey, medicinal plants, Togo
ARTICLE
BRCA1 and BRCA2 Gene Mutations in Breast Cancer among West African Women
Zouré A.A, Bambara H.A, Sawadogo A.Y, Bakri Y, Simporé J
There is an increase in the prevalence of cancer in Africa, while cancer was previously related to the industrialized countries. In
fact, until today studies are scanty in all the African regions to find out more about the reality of the disease. However, in West
Africa, there are few reports on the genetic factors of breast cancer. Our revi(...)
Breast cancer- Genetic risks- BRCA1/2- West Africa
ARTICLE
Sero-prevalence and risk factors for hepatitis E virus infection among pregnant women in the Cape Coast Metropolis, Ghana
Dorcas Obiri-Yeboah, Yaw Asante Awuku, Joseph Adu, Faustina Pappoe, Evans Obboh, Paul Nsiah, Daniel Amoako-Sakyi, Jacques Simpore
Background: Hepatitis E virus is an emerging infection in Africa with poor maternal and foetal outcomes. There is scanty data on the sero-prevalence of HEV infection among pregnant women in Ghana. This study highlighted the prevalence and risk factors associated with HEV infection among pregnant women in Cape Coast Metropolis, Central Region o(...)
Hépatite E ; Séroprévalence ; Femmes enceintes ; Ghana ; Risques maternels et néonatals
ARTICLE
Breast cancer: descriptive profile of 80 women attending breast cancer care in the Department of General and Digestive Surgery of CHU-YO
Hierrhum Aboubacar Bambara, Abdou Azaque Zouré, Alexis Yobi Sawadogo, Abdoul Karim Ouattara, Nabonswindé Lamoussa Marie Ouédraogo, Si Simon Traoré, Youssef Bakri, Jacques Simpore
Introduction: Breast cancer is a common cause of death among women in Burkina Faso. The aim of this study was to determine a descriptive profile of 80 women and establish a description of risk factors associated with breast cancer in these women.
Methods: This cross-sectional study recruited women with breast cancer in Ouagadougou. Teaching(...)
Breast cancer; Burkina Faso; descriptive profile; risk factors.
ARTICLE
Identification and Antibioresistance Characterisation of Culturable Bacteria in the Intestinal Microbiota of Mosquitoes
Yerbanga RS, Aminata Fofana, Mathilde Gendrin, Ibrahim Sangare, Soufiane Sanou, Soumeya Ouangraoua, Somé AF, Aly Drabo, Jacques Simpore, Thierry Lefèvre, Anna Cohuet, George Christophides, Ouédraogo JB
Background: The bacterial microbiota which colonize the mosquito midgut play an important role in vector-parasite interactions and consequently can modulate the level of malaria transmission. Their characterization may contribute to new control strategies of malaria transmission. However, these bacteria may also be eliminated in areas of high(...)
Escherichia coli; Klebsiella pneumonia;Pseudomonas luteola
ARTICLE
ANTIBACTERIAL AND ANTI-INFLAMMATORY ACTIVITIES OF CRUDE EXTRACTS OF THREE TOGOLESE MEDICINAL PLANTS AGAINST ESBL KLEBSIELLA PNEUMONIAE STRAINS
Gerard A. Toudji, Emmanuel Thiombiano, Simplice D. Karou, Kokou Anani, Yao Adjrah, Holaly E. Gbekley, Martin Kiendrebeogo, Yaovi Ameyapoh, Jacques Simpore
Background: Pithecellobium dulce (Roxb.) Benth., Securidaca longepedunculata Fresn and Cryptolepis sanguinolenta (Lindl.) Schlt are three plants widely used in the Togolese traditional medicine to treat microbial infections. Some studies reported their antibacterial activity alone but until know there no data concerning their possible interact(...)
antibiotics, extended-spectrum beta lactamase, plant extract, bacteria, Togo
ARTICLE
SEROLOGICAL DIAGNOSIS IN SUSPECTED DENGUE CASES AT SAINT CAMILLE HOSPITAL OF OUAGADOUGOU: HIGH PREVALENCE OF INFECTION AMONG YOUNG ADULTS AGED 15 TO 30 YEARS
Abdoul Karim Ouattara, Christelle Nadembega, Birama Diarra, Theodora Zohoncon, Albert Yonli, Dorcas Obiri-Yeboah, Marius Belemgnegre, Paul Ouedraogo, Virginio Pietra, Jacques Simpore
Dengue fever is currently a major public health problem in Burkina Faso. The aim of this study was
to determine seroprevalence and dengue infection evolution during the years 2016 and 2017. The
study population consisted of 3572 patients aged 0 to 84 years seen at in general medicine
consultation from January 2016 to November 2017 and refer(...)
Dengue, Ns1Ag, Seroprevalence, Burkina Faso
ARTICLE
Socioeconomic differences in disability by age in sub-Saharan Africa: A cross-national study using the World Health Survey
Yentéma Onadja, Simona Bignami, Maria-Victoria Zunzunegui
This study aims to examine the relationship between socio-economic status (as measured by education) and multiple disability measures among adults in eighteen sub-Saharan African countries, and to determine whether the strength of this relationship varies across age groups. The analysis uses data drawn from the 2002–04 World Hea(...)
Mots clés non renseignés
ARTICLE
Thyroid disorders among older people in burkina faso
Christelle Nadembega, Abdoul Karim Ouattara, Birama Diarra, Dorcas Obiri-Yeboah, Théodora Zohoncon, Virginio Pietra, Jacques Simpore
Introduction: Thyroid disorders are common in adults with significant clinical consequences. The objective of this study was to estimate the prevalence of biochemical hyperthyroidism and hypothyroidism in older people in Ouagadougou, Burkina Faso. Material and Methods: This was a retrospective analysis of thyroid function tests results of peop(...)
TSH, FT4, Hyperthyroidism, Hypothyroidism, Elderly, Burkina Faso
ARTICLE
ETHNOBOTANICAL STUDY OF PLANTS USED TO TREAT ASTHMA IN THE MARITIME REGION IN TOGO
Holaly E. Gbekley, Gnatoulma Katawa, Simplice D. Karou, S. Kokou Anani, Tchacondo Tchadjobo, Yaovi Ameyapoh, Komlan Batawila, Jacques Simpore
Background: Asthma is one of the most common chronic diseases in modern society and it is evident that its incidence and severity are increasing, however very little is known about the plants used in the management of the disease. This study therefore aimed to document the plants usage in the Togolese traditional medicine to treat asthma.
M(...)
Asthme ; Togo ; plantes médicinales ; enquête ; médecine traditionnelle
ARTICLE
Acute and sub-acute toxicity of Pithecellobium dulce (Roxb.) Benth. stem bark hydroalcoholic extract on Wistar rats
Gérard A. Toudji, Kossivi Dosseh, Simplice D. Karou, Yao Adjrah, Kokou Anani, Yaovi Ameyapoh, Jacques Simpore
Context: Pithecellobium dulce (PD) is an annual herbaceous plant
commonly used in African traditional medicine as a purgative,
antipyretic, anti-ulcer and wound dressing agent.
Aims: To evaluate the acute and sub-acute toxicity of P. dulce stem bark
hydroethanolic extract in Wistar rats.
Methods: In the acute test, a single dose of 5 g/kg(...)
animal model; medicinal plants; pharmacology; toxicology.
ARTICLE
Prevalence and resistance profile of extended-spectrum β-lactamases-producing Enterobacteriaceae in Ouagadougou, Burkina Faso
Dissinviel Stéphane Kpoda, Nathalie Guessennd, Juste Isidore Bonkoungou, Mohamed Baguy Ouattara, Fernique Konan, Abraham Ajayi, Jacques Simpore, Rasmata Ouedraogo, Koiné Maxime Drabo, Lassana Sangare, Mireille Dosso, Alfred Traore
Increasing bacterial resistance to antimicrobial agents has become an issue of concern. A major problem of the treatment of infections caused by Enterobacteriaceae using antibiotics is the emergence of Extended-spectrum β-lactamases (ESBL)-producing Enterobacteriaceae. This study aims to determine the prevalence of ESBL-producing Enterobacteri(...)
Enterobacteriaceae, Extended-Spectrum Beta-lactamases (ESBL), Burkina Faso.
ARTICLE
Medicinal Plants Used for Neuropsychiatric Disorders Treatment in the Hauts Bassins Region of Burkina Faso
Prosper T. Kinda, Patrice Zerbo , Samson Guenné , Moussa Compaoré, Alin Ciobica and Martin Kiendrebeogo
Background: In Burkina Faso, phytotherapy is the main medical alternative used by populations to manage various diseases that affect the nervous system. The aim of the present study was to report medicinal plants with psychoactive properties used to treat neuropsychiatric disorders in the Hauts Bassins region, in the western zone of Burkina Fa(...)
Neuropsychiatry, phytotherapy, traditional healers, Burkina Faso
ARTICLE
Evaluation de la qualité hygiénique de quelques recettes antidiabétiques
GBEKLEY Efui Holaly, Soncy Kouassi, Karou Simplice Damintoti, Djéri Bouraima, Agbodéka Kodjovi, Ameyapoh Blaise, Jacques Simpore, de Souza Comlan Aristide, Gbeassor Messanvi
Objectives of the study: The Assessment of hygienic quality is an essential step in the production and marketing of traditional medicine products using plant species that constitute a vast reserve of active ingredients that can be used to cure many diseases. Our study had the objective to assess the hygienic quality of some herbal medicines in(...)
Keywords: Diabetes Mellitus (DM), herbal medicines, microbiological quality, bacteria, AFNOR, Togo.
ARTICLE
Composés bioactifs isolés des plantes à propriété anti-diabétique: Revue de littérature
GBEKLEY Efui Holaly, Kodjovi AGBODEKA, Karou Simplice Damintoti, Kokou ANANI, Adjrah Yao, Toudji Gérard, Ameyapoh Blaise, Jacques Simpore, Gbeassor Messanvi
Diabetes (diabetes) is a disease (or rather syndrome) Endocrine most prevalent. It is estimated diabetics to more than 100 million worldwide and this figure and the percentage of the affected population are steadily increasing (around 6% in the "rich" countries). non-insulin-dependent diabetes (type 2, fatty diabetes or the elderly) that are r(...)
Hypoglycemic compounds, plants, chemical structures, diabetes mellitus, phototherapy.