Publications (234)
ARTICLE
Determination of groundwater mercury (II) content using a disposable gold modified screen printed carbon electrode
Touridomon Issa Some, Abdoul Karim Sakira, Dominique Mertens, Sebastien N. Ronkartand Jean-Michel Kauffmann
Mercury (II) measurements were performed thanks to a newly developed electrochemical method using a disposable gold modified screen printed carbon electrode. The method has a wide dynamic range (1–100 µg/L), a good accuracy and a limit of detection in compliance with WHO standards. The application of the method to several groundwater samples m(...)
Mots clés non renseignés
COMMUNICATION
Using new vaccine introduction as entry point for strengthening AEFI surveillance systems Lessons learned with MenAfriVac® in Burkina Faso
Dr Emile W. OUEDRAOGO
Dr Emile Ouédraogo of Burkina Faso reported how the introduction of a new vaccine – the meningitis vaccine MenAfriVac – provided an opportunity to strengthen the country’s AEFI surveillance system. Prior to this, training on spontaneous reporting of adverse drug reactions for malaria and HIV/TB medicines had been funded by the Global Fund, and(...)
AEFI, Vaccine, Burkina Faso, MenAfrivac
ARTICLE
MAP Kinase cross talks in oxidative stress-induced impairment of insulin secretion. Involvement in the protective activity of quercetin
Estelle Youl, Richard Magous, Gerard Cros, Catherine Oiry
Insulin secretion preservation is a major issue for the prevention or treatment of type 2 diabetes. We previously showed on b-cells that quercetin (Q), but not resve- ratrol (R) or N-acetyl cysteine (NAC), amplified glucose-induced insulin secretion in a calcium- and ERK1/2-dependent manner. Quercetin, but not resveratrol or NAC, also protecte(...)
Insulin secretion, MAP kinase cross talks, oxidative stress, quercetin, b-cell
ARTICLE
Determination of arsenic (III) at a nanogold modified solid carbon paste electrode
Abdoul Karim Sakira, Touridomon Issa Some, Bieke Dejaegher, Dominique Mertens, Philippe Hubert, Eric M Ziemons and Jean‐Michel Kauffmann
A selective and sensitive electroanalytical method was developed for arsenic determination based on a nanogold (AuNP) modified solid carbon paste working electrode (SCPE) modified in two steps (i) physisorption and (ii) additional electrodeposition of nanogold particles in the presence of iodide. Copper (II) interference was solved by covering(...)
Mots clés non renseignés
ARTICLE
Determination of β-carotene by High Performance Liquid Chromatography in Six Varieties of Mango (Mangifera indica L) from Western Region of Burkina Faso
Touridomon Issa Somé, Abdoul Karim Sakira and Eric Dofinizoumou Tamimi
Six varieties of mangoes (Amelia, Brooks, Kent, Keitt, Lippens, Springfield) harvested from different pedological areas of the western region of Burkina Faso (Bobo-Dioulasso, Orodara, Banfora) were analyzed by high performance liquid chromatography in order to determine the β-carotene content. The study revealed a variability in β-carotene con(...)
Mots clés non renseignés
ARTICLE
Effect of cyclodextrins on artemisinin stability and in vitro dissolution
H Zime-Diawara, F Gbaguidi, R Semde, I Some, J Quetin-Leclercq, M Moudachirou, G Piel and B Evrard
Artemisinin is extracted from the Asian plant Artemisia annua L. It has been proven to be, with its derivatives, the molecules that have shown so far the most powerful activity on malaria, even in its complicated forms and resistance cases. To resolve the problem of low aqueous solubility of this molecule, the use of cyclodextrins (CDs) was en(...)
Mots clés non renseignés
ARTICLE
Study of Antisickling and Vasorelaxant Activities and Acute Toxicity Assessment of Crude Extracts of Leaves of Ficus sycomorus L. (Moraceae)
Alphonsine Ramde-Tien, André Tibiri, Moussa Ouédraogo, Sylvin Ouedraogo ., Odile Germaine Nacou ., Innocent Pierre Guis .
The leaves of Ficus sycomorus are used in Burkina Faso folk medicine for the treatment of sickle cell disease. The present comparative study of crude extracts of leaves (decoction, macerated extract and a 95% ethanol extract) was performed with the aim to assess the efficiency of this traditional use and to determine the most active of the thr(...)
Acute toxicity, Moraceae, Decoction, Traditional medicine, Crude drug, Chemistry, Pharmacology, Toxicity, Medicine
ARTICLE
A Survey of Arsenic Level in Tube-Wells in Bam Province (Burkina Faso)
Touridomon Issa Somé, Abdoul Karim Sakira, Alidou Kaboré, Aissata Traoré
Groundwater is a main source of water supply for populations in Burkina Faso where there is a serious problem for drinking water access. However, water quality has not been always followed regularly. Recent studies showed that more than 50% of drillings in Yatenga province (north of Burkina Faso) have an arsenic concentration above the recomme(...)
Arsenic, Groundwater, Environmental science, Water supply, Arsenic contamination of groundwater, Water well, Water quality, Environmental engineering, Water source, Water resource management, Geography, Environmental protection, Engineering, Chemistry
ARTICLE
Arsenic levels in tube-wells water, food, residents' urine and the prevalence of skin lesions in Yatenga province, Burkina Faso
Issa T. Somé,1 Abdoul K. Sakira, Moustapha Ouédraogo, Theodore Z. Ouédraogo, Adama Traoré, Blaise Sondo and Pierre I. Guissou2
The aim of the present study was to evaluate the levels of arsenic in tube-well water, food and residents' urines samples in Yatenga province, Burkina Faso. The prevalence of skin lesions was evaluated as well. The study was cross-sectional in design. It was conducted during April 2009. Permanent residents of 20 villages were included in the s(...)
Mots clés non renseignés
ARTICLE
Protective effect of Moringa oleifera leaves against gentamicin-induced nephrotoxicity in rabbits
Moustapha Ouédraogo, Assita Lamien-Sanou, Norbert Ramdé, Aimé Sosthène Ouedraogo, Moussa Ouédraogo, Salifou P. Zongo, Olga Goumbri, Pierre Duez, Pierre I. Guissou
Oxidative stress due to abnormal production of reactive oxygen species has been implicated in the nephrotoxicity induced by gentamicin. The nephroprotective effect of aqueous-ethanolic extract of Moringa oleifera leaves (150 and 300 mg/kg) was evaluated against gentamicin-induced (80 mg/kg) renal injury in rabbits. Serum urea and creatinine le(...)
Gentamicin Nephrotoxicity Lipid peroxidation Nephroprotection Moringa oleifera
ARTICLE
An Overview of Cancer Chemopreventive Potential and Safety of Proanthocyanidins
Moustapha Ouédraogo, Catherine Charles, Moussa Ouédraogo, Innocent Pierre Guissou, Caroline Stévigny, Pierre Duez
Cancer is a major public health problem worldwide. Over two-thirds of cancer-related deaths could most probably be prevented through lifestyle modification, particularly through dietary means. Proanthocyanidins (PAs), the most abundant polyphenolic substances after lignin in the plant kingdom, have been widely investigated for their chemopreve(...)
Cancer, Proanthocyanidin, Web of science, Polyphenol, Medicine, Cancer research, Antioxidant, Traditional medicine, Chemistry, Pharmacology, Biochemistry, Internal medicine, MEDLINE
ARTICLE
Acute toxicity and anti-inflammatory activity of aqueous ethanol extract of root bark of Ximenia americana L. (Olacaceae)
Onifade Al-fattah Olabissi, Moussa Ouédraogo, Moustapha Ouédraogo, Zongo Frank Edgard, Kaf, o Eleonore, Marius Lompo, Guissou Innocent Pierre
Ximenia americana L. (Olacaceae) is a folk medicinal plant used in Burkina Faso to treat inflammatory, noxious and infectious diseases. The aim of this study was to evaluate anti-inflammatory properties of aqueous ethanol extract of root bark of the plant and evaluate its acute toxicity. Carrageenan was used to induce oedema and leukocyte migr(...)
Ximenia americana, anti-inflammatory activity, acute toxicity, root bark.
ARTICLE
Contribution of a tyrosine-based motif to cellular trafficking of wild-type and truncated NPY Y1 receptors
Sandra Lecat, Moussa Ouédraogo, Thomas Cherrier, Fanny Noulet, Philippe Rondé, Nicole Glasser, Jean‐Luc Galzi, Yves Mély, Kenneth Takeda, Bernard Bucher
The human NPY Y1 receptor undergoes fast agonist-induced internalization via clathrin-coated pits then
recycles back to the cell membrane. In an attempt to identify the molecular determinants involved in this
process, we studied several C-terminal truncation mutants tagged with EFGP. In the absence of agonist, Y1
receptors lacking the last(...)
Neuropeptide Y Y1 receptor G protein-coupled receptors Internalization Constitutive internalization Recycling
ARTICLE
Quercetin potentiates insulin secretion and protects INS-1 pancreatic b-cells against oxidative damage via the ERK1/2 pathway
E Youl, G Bardy, R Magous, G Cros, F Sejalon, A Virsolvy, S Richard, JF Quignard, R Gross, P Petit, D Bataille and C Oiry
BACKGROUND AND PURPOSE
Quercetin lowers plasma glucose, normalizes glucose tolerance tests and preserves pancreatic b-cell integrity in diabetic rats. However, its mechanism of action has never been explored in insulin-secreting b-cells. Using the INS-1 b-cell line, the effects of quercetin were determined on glucose- or glibenclamide-induced(...)
quercetin; pancreatic b-cells; insulin secretion; cell viability; ERK1/2; oxidative stress; diabetes
ARTICLE
Development of an in vitro Endotoxin Test for Monoolein–Water Liquid Crystalline Gel for Use as an Implant
Moustapha Ouédraogo, Rasmané Semdé, Touridomon Issa Some, Rasmata Ouédraogo, Viviane Henschel, Brigitte Evrard, Jacques Dubois, Karim Amighi and Innocent P Guissou
Purpose: Drugs that are administered by parenteral route must be apyrogenic. The aim of this study was to develop an in vitro endotoxin test for liquid crystalline gels for use as implants, using a monoolein–water liquid crystalline gel as a model. Methods: The gel-clot technique was used. The gel was dissolved first in isopropyl myristate, an(...)
Mots clés non renseignés