Publications (375)
ARTICLE
Prevalence and Characterization of High-Risk Human Papillomavirus Genotypes among a Group of Sex Workers in Ouagadougou, Burkina Faso
Régine Ilboudo, Esther MA Traoré, Théodora Mahoukèdè Zohoncon, Rogomenoma Alice Ouédraogo, Ina Marie Angèle Traore, Prosper Bado, Clarisse Ouédraogo, Florencia Wendkuuni Djigma, Dorcas Obiri-Yeboah, Jean Sakandé, Jacques Simporé, Charlemagne Ouedraogo
Background: Human papillomavirus (HPV) is the most common cause of cervical cancer worldwide. The aim of this study was to
determine the prevalence and to characterize circulating high-risk HPV genotypes among female sex workers in Ouagadougou.
Patients and Methods: A total of 200 sex workers voluntarily agreed to take part in this study and(...)
Sex-Workers; HPV; Genotypes; PCR
ARTICLE
Pharmacokinetics of plasma lopinavir and ritonavir in tuberculosis-HIV co-infected African adult patients also receiving rifabutin 150 or 300 mg three times per week
Henri Gautier Ouedraogo, Alberto Matteelli, Giorgia Sulis, Tegwinde Rebeca Compaore, Serge Diagbouga, Simon Tiendrebeogo, Alberto Roggi, Kadari Cisse, Pier Francesco Giorgetti, Paola Villani, Lassana Sangare, Jacques Simpore, Mario Regazzi, Seni Kouanda
Background: To evaluate the pharmacokinetic of plasma lopinavir (LPV) and ritonavir (RTV) when co-administered with three times weekly (TPW) rifabutin (RBT) at a dose of either 150 or 300 mg in African tuberculosis (TB) and HIV co-infected adult patients.
Methods: This is a pharmacokinetic study conducted in Ouagadougou among patients treat(...)
Co-infection ; HIV–tuberculosis ; Lopinavir ; Pharmacokinetic ; Rifabutin ; Ritonavir
ARTICLE
Prevalence of Plasmodium falciparum Chloroquine Resistance Transporter (Pfcrt76T) Mutation Associated with Antimalarial Drug Resistance in Two Different Epidemiological Setting (Banfora and Saponé) in Burkina Faso Few Years after the Implementation of Artemisnine Based Combination Therapy (ACTs)
Séni Nikiema, Samuel Sindié Sermé, Salif Sombié, Amidou Diarra, Noelie Bere Henry, Emilie Salimata Badoum, Sam Aboubacar Coulibaly, San Maurice Ouattara, Jean Moise Kaboré, Florencia Wendkuuni Djigma, Sodiomon Bienvenu Sirima, Jacques Simpore, Issiaka Soulama
Introduction: In spite of considerable progress, malaria remains a public health problem in many areas, particularly in sub-Saharan Africa. One major complexity of malaria disease is caused by the development and the spread of vector and parasite resistance to insecticides and antimalarial drugs respectively. The Pfcrt76T gene mutation has bee(...)
Plasmodium falciparum, antimalarial drugs, Pfcrt gene, ACTs, Banfora, Saponé, resistance
ARTICLE
Protection afforded by sickle-cell trait against asymptomatic malarial infection in Burkina Faso
Valerie B. Bazie, Theodora M. Zohoncon, Tani Sagna, Abdoul Karim Ouattara, Florencia W. Djigma, Jacques Simpore
Background: Malaria is a major public health problem in Burkina Faso because every yearthe burkinabè population continue to bear a heavy burden. Malaria infection depends on the parasite's ability to interact with the host's red blood cells for its development. In population living in malaria endemic areas, sickle cell trait (HbAS, HbAC and Hb(...)
sickle-cell trait, malaria, asymptomatic infection, Burkina Faso, Plasmodium falciparum
ARTICLE
Coexistence between (TOHO-type and BES-type) extended-spectrum β-lactamase genes of identified enterobacteria at Saint Camille Hospital, Ouagadougou, West Africa
Mètuor-Dabiré Amana Sougué, Serge Tiemtoré, Rahimatou Yasmine Wend-Kuni, Zohoncon Théodora Mahoukèdè, Bangré Yasmine Aminata, Ouédraogo Paul, Kabré Elie, Simporé Jacques
Coexistence between the TOHO-type and Brazilian extended-spectrum (BES)-type of extended-spectrum β-lactamase (ESBL)-produced by bacteria caused public health issue. Several studies have been reported on the coexistence between blaTEM, blaCTX-M and blaSHV genes in ESBL in broad spectrum enterobacteria. The present study involved the prevalence(...)
Antibiotic, resistance, extended-spectrum β-lactamase (ESBL), genes, TOHO, Brazilian extended-spectrum (BES).
ARTICLE
Prevalence of lower genital tract infections in women: case of saint camille hospital of ouagadougou from 2015 to 2018
Tovo S. Frida, Ouattara Abdoul Karim, Zohoncon M. Theodora, Obiri-Yeboah Dorcas, Yonli A. Theophane, Djigma W. Florencia, Sangaré Lassana, Simpore Jacques
Background: Vaginal infections remain a major public health problem in Burkina Faso. A retrospective study was conducted at Saint Camille Hospital of Ouagadougou (HOSCO) to determine the prevalence and risk factors associated with vaginal infections in women seen at gynecological consultation between 2015 and 2018. Methods: This is a retrospec(...)
Infections génitales basses, Candida albicans, Enterococcus spp., résistance antifongique, Ouagadougou
ARTICLE
Identification of Synthetic Cannabinoids 5F-ADB and XLR-11 in Seized Sample in Penang, Malaysia
Choon Hiang Ng, Siti Aishah Che Ani, Khairuzzaman Mustafa, Shaari Desa, Maimonah Sulaiman
(This is a hypothetical example based on the title since the abstract was not provided explicitly):
This study reports the forensic identification of two synthetic cannabinoids, 5F-ADB and XLR-11, found in seized drug samples in Penang, Malaysia. The compounds were analyzed using advanced chromatographic and spectrometric techniques, confir(...)
Synthetic Cannabinoids, 5F-ADB, XLR-11, Forensic Analysis, Seized Sample, Malaysia
ARTICLE
DISTRIBUTION OF FINGERPRINTS PATTERNS AMONG A COHORT OF POPULATION IN OUAGADOUGOU, BURKINA FASO
Missa Millogo, Seydou Ouattara, Noufou Salou, Moctar Zeba, Adama Ouedraogo, David Zongo, Prosper Kinda, Paulin Nana, Fulgence Badiel, Jacques Simporé
Based on their strictly individual and immutable characters, fingerprints are indispensable tool for
person’s identification. In forensic science, digital pattern families constitute the first level of comparison
between an incriminated digital trace and a suspect fingerprint. Until now in the literature, there was no data on
the distributi(...)
Fingerprints, pattern distribution, forensic science, population study, Burkina Faso
ARTICLE
Circulating High-risk HPV Genotypes in the South of Benin and Disparity with General Immunization Target
Marie-Marthe A. Chabi, Callinice D. Capo-Chichi, Théodora M. Zohoncon, Christine Aguemon, Ambaliou Sanni, Jacques Simporé
High-Risk Oncogenic Human Papillomaviruses (HR-HPV) are accountable for 7.7% of
cancers in developing countries, mainly cervical lesions. In Benin, HR-HPV infection in women triggered nearly
781 new cases of cervical cancer each year leading to 616 (79%) deaths. Current vaccines may not cover all
HR-HPV genotypes encountered in West Africa(...)
Circulating HPV, high-risk genotypes, South of Benin, immunization, HPV vaccine, epidemiology
ARTICLE
Ethnomedicinal and Pharmacognostical Investigation on Three Medicinal Asteraceae Species from Burkina Faso: Bidens Engleri O. E. Schulz, Acanthospermum hispidum DC. and Ageratum conyzoides L.
Bagora Bayala, Adama Hilou, Pierre A. E. D Sombié, Ahmed Y. Coulibaly, Odile Nacoulma, Jacques Simporé
Aims: This study aimed to collect data on ethnomedicinal uses and pharmacognostic evaluation of Bidens engleri, Ageratum conyzoides, and Acanthospermum hispidum, three species of the Asteraceae family commonly found in Burkina Faso.
Methods: Ethnomedicinal data were collected through questionnaires, interviews, and discussions with local la(...)
Ethnomedicinal, pharmacognostical, Asteraceae, Bidens engleri, Acanthospermum hispidum, Ageratum conyzoides, Burkina Faso
ARTICLE
Successful Closure of Patent Ductus Arteriosus by Late Pharmacologic Treatment in a Small Preterm Infant
Boro Theodore, Ouedraogo Paul, Bama Aime, Seghda Arthur, Zagre Nicaise, Zabsonre Patrice, Simpore Jacques
The ductus arteriosus (DA) is a temporary communicative pathway that connects the pulmonary artery to the aorta during fœtal life. Although usually closing on its own in the initial days of postnatal life, the persistent patency of the DA is common in preterm or low birth weight babies, and can lead to life-threatening complications. Early dia(...)
Patent Ductus Arteriosus, Preterm Infant, Ibuprofen
ARTICLE
Mspi polymorphisms (rs4646903) of the cyp1a1 gene in women infected with human papillomavirus in West Africa
Mah Alima Esther TRAORE, Wendkuuni Florencia DJIGMA, Marius Ayaovi SETOR, Théodora Mahoukèdè ZOHONCON, Dorcas OBIRI-YEBOA, Abdoul Karim OUATTARA, Pegdwendé Abel SORGHO, Prosper BADO, Albert Théophane YONLI, Apollinaire HORO, Moutawakilo GOMINA, Mady NAYAMA, Souleymane OUATTARA, Simon AKPONA, Simplice Damintoti KAROU, Charlemagne OUEDRAOGO, Jacques SIMPORE
Background: Human papillomavirus (HPV) infection alone is not enough to induce malignant transformation due to viral clearance. Genetic factors could play a very important role in the progression. Genes such as cytochrome P450 1A1 (CYP1A1) could affect the progression of cervical lesions. The objectives of this study were to screen HPV-positiv(...)
HR-HPV, Genotypes, CYP1A1, MspI, Real-Time PCR, RFLP, West Africa
ARTICLE
Study of Viral Load as A Predictive Marker of the Evolution of HIV Type 2 Infection in Burkina Faso
Mahamoudou Sanou, Absatou Ba/Ky, Assane Neya, Albert T Yonli, Dufrasne François, Jean Ruelle, Benoit Kabamba, Bolni Marius Nagalo, Mamadou Tamboura, Dinanibe Kambiré, Patric Goubau, Rasmata Traore, Jacques Simporé
Background: HIV - 2 infection is characterized by low sexual and vertical transmission and slow clinical and immunological progression. However, it can lead to AIDS. Viral load measurement is a predictive test of the success or failure of antiretroviral therapy. In
order to evaluate the efficacy of ARV treatment, we measured plasma viral load(...)
HIV-2; Viral Load; CD4 T Cells; Antiretroviral
ARTICLE
Molecular Epidemiology of High-Risk Human Papilloma Virus Infection in Sexually Active Women at Bobo-Dioulasso University Teaching Hospital
Souleymane Ouattara, Der Adolphe Somé, Adama Dembélé, Salif Sanfo, Théodorat Zohoncon, Abdoul-Karim Ouattara, Moussa Bambara, Blami Dao, Jacque Simporé
The objective of this study was to determine the prevalence of HPV-HR genotypes in the population of sexually active women in Bobo-Dioulasso, Burkina Faso. Methods: This study took place at Souro Sanou Teaching Hospital in Bobo-Dioulasso from September to June 2017. A total of 234 women in the gynecological period and also sexually active were(...)
HPV-HR, Epidemiology, Genotypes, Bobo-Dioulasso
ARTICLE
Detection of multidrug-resistant enterobacteria simultaneously producing extended-spectrum β-lactamases of the PER and GES types isolated at Saint Camille Hospital Center, Ouagadougou, Burkina Faso
Mètuor Dabiré Amana, Tiemtoré Rahimatou Yasmine Wend-Kuni, Bangré Yasmine Aminata, Zohoncon Théodora Mahoukédé, Sougué Serge, Zongo Jacob Koudbi, Simporé Jacques
Resistance to a wide variety of common antibiotics is observed among clinical strains designated as extended-spectrum β-lactamase (ESBL) producers. These produce enzymatic proteins that effectively inactivate cephalosporins and aztreonam and are a serious global health problem that complicates treatment strategies. Many studies report a high p(...)
Broad-spectrum beta-lactamases (ESBLs), Pseudomonas extended resistance (PER) gene, Guiana extended-spectrum (GES) gene, Polymerase chain reaction (PCR)