Publications (128)
ARTICLE
Pharmacological Evaluation of the Bronchorelaxant Effect of Waltheria indica L. (Malvaceae) Extracts on Rat Trachea
Rainatou Boly , Zakaline Yabre, Mathieu Nitiema , Boubacar Yaro, Jules Yoda, Lazare Belemnaba , Sylvain Ilboudo, Noëla Hoho Estelle Youl, Innocent Pierre Guissou, and Sylvin Ouedraogo
Waltheria indica L. (Malvaceae) is a plant used in Burkina Faso for the treatment of various ailments including asthma. The aim of the study was to evaluate the pharmacological relaxant effect of the leafy stem extracts of Waltheria indica and thereby verify claim of use in treating asthma. Aqueous decoction and hydroalcoholic extracts obtaine(...)
Bronchorelaxant effect, Waltheria indica L., Rat trachea
ARTICLE
Quality assessment of individual case safety reports in pharmacovigilance in Burkina Faso
Nazaire Roamba1,*, Emile Windné Ouedraogo3and Estelle Noella Hoho Youl2,4
Pharmacovigilance is based on individual case safety reports. Our study is intended to be a
contribution to good practices by the quality assessment of individual case safety reports sent to
the National Center for Vigilance in Burkina Faso. We carried out a cross-sectional study which
concerned individual case safety reports sent to the Ce(...)
Adverse effects, Drugs, WHO grade, Pharmacovigilance, Burkina Faso
ARTICLE
Study of manufacturing conditions of medicines derived from traditional pharmacopoeia in Benin and Burkina Faso
D. Dori, H.W.B. Ouedraogo, P.D. Houngue, F.A. Gbaguidi, B. Evrard, J. Quetin-Leclercq, R. Semdé
Introduction : La médecine traditionnelle est devenue un maillon important du système de soins des populations
africaines. De nombreux produits qui en sont issus sont de plus en plus utilisés dans l’arsenal thérapeutique. Ce travail fait l’état des lieux de la production de ces médicaments dans deux pays de l’Afrique de l’Ouest, le Burkina Fa(...)
Médecine traditionnelle; Pharmacopée traditionnelle ; Médicaments; Production; Matière première ; Burkina Faso ; Bénin
ARTICLE
Sterilization methods of liposomes: Drawbacks of conventional methods and perspectives
Kouka Luc Delma, Anna Lechanteur, Brigitte Evrard, Rasmané Semdé, Géraldine Piel
Liposomes are targeted drug delivery systems that are of great pharmaceutical and therapeutic interest.
Parenteral route is the main way used for liposome administration. In this case, their sterility is a requirement.
However, due to the particular sensitivity of liposomes and their tendency to physicochemical alterations, their
sterilizat(...)
Liposome, Sterilization, Conventional methods, Supercritical carbon dioxide
ARTICLE
Identification of Five Acylated Anthocyanins and Determination of Antioxidant Contents of Total Extractsof a Purple-Fleshed Ipomoea batatasL. Variety Grown in Burkina Faso
Dominique Saga Kaboré, Adama Héma, Elie Kabré, Raoul Bazié, Abdoul Karim Sakira, Moumouni Koala, Paul-André Koussao Somé, Eloi Palé, Touridomon Issa Somé, Pierre Duez and Mouhoussine Nacro
Kaboré et al.; IRJPAC, 22(7): 48-66, 2021; Article no.IRJPAC.7380049ABSTRACTAnthocyanins are bioactive compounds, which thanks to their anti-free radical properties, can protect the human body against oxidative stress. The latter can cause many diseases, such as cancer, aging. The extract of the green cap purple variet(...)
Mots clés non renseignés
ARTICLE
Evaluation of antimycobacterial activity of medicinal plants used by Malian traditional medicine practitioners to treat tuberculosis
Mahamadou Ballo, Anou M. Somboro , Mamoudou Maiga, Bassirou Diarra , Moumine Sanogo, Adama Denou, Adiaratou Togola, Estelle N. H. YOUL, Sekou Bah, Rokia Sanogo and Drissa Diallo
Global Tuberculosis (TB) control is facing major challenges such as occurrence of multidrug-resistant (MDR) and extensively drug-resistant tuberculosis (XDR). The current TB drugs are getting less effective and associated with side effects limiting their use, especially with MDR and XDR infected patients. In Mali, many medicinal plants are use(...)
Medicinal plants, Mycobacterium tuberculosis H37Rv, Mali.
ARTICLE
Quantitative determination of chemical and biochemical parameters during « soumbala » manufacturing process in two communities of Burkina Faso
Elie KABRÉ, Moumouni BANDÉ, Raoul KARFO, Raoul BAZIÉ, Doulmouhaye SOULAMA, Fulbert NIKIÉMA et Jean SAKANDÉ
« Soumbala » is traditionally used in Burkina Faso as a food condiment in different communities. This
study was conducted to evaluate « soumbala » manufacturing process on its nutritional value in two communities.
During this descriptive and analytical study, samples were taken in the « Gouin » and « Moose » communities.
The results show(...)
Burkina Faso, « soumbala », biochemical parameters
ARTICLE
Effectiveness of seasonal malaria chemoprevention at scale in west and central Africa: an observational study
ACCESS-SMC Partnership*
Summary
Background Seasonal malaria chemoprevention (SMC) aims to prevent malaria in children during the high malaria
transmission season. The Achieving Catalytic Expansion of SMC in the Sahel (ACCESS-SMC) project sought to
remove barriers to the scale-up of SMC in seven countries in 2015 and 2016. We evaluated the project, including
cover(...)
Mots clés non renseignés
ARTICLE
Determination of the quality of metronidazole formulations by near-infrared spectrophotometric analysis
Abdoul Karim SAKIRA, Corenthin MEES, Kris De BRAEKELEER, Cédric DELPORTE, Josias YAMEOGO, Moussa YABRE , Touridomon Issa SOME , Pierre Van ANTWERPEN , Dominique MERTENS , Jean Michel KAUFFMANN
In the quality control of medicines and the fight against the phenomenon of poor quality medicines, there is an urgent need for rapid and broad spectrum methods for screening these types of medicines. In the present work, we have used near infrared spectroscopy combined with multivariate data analysis to develop chemometric models for the clas(...)
Mots clés non renseignés
ARTICLE
Évaluation des capacités nationales de contrôle de la qualité des médicaments à base de plantes en Afrique de l’Ouest : cas du Benin et du Burkina Faso
Dori Daniel, Assanhou Gabin A, Gbaguidi Fernand A, Evrard Brigitte, Quetin-Leclercq Joëlle, Semdé Rasmané
Objectif : Evaluer les capacités nationales de contrôle qualité des médicaments à base plantes médicinales au Bénin et au Burkina Faso. Matériels et Méthode : étude transversale descriptive, par enquête auprès des 33 établissements de fabrication et des 5 laboratoires indépendants de contrôle de qualité répertoriés dans les deux pays. Résultat(...)
Médicament à base de plantes; médecine traditionnelle; matières premières; contrôle qualité; Bénin; Burkina Faso
ARTICLE
Hypoglycemic and antihyperglycemic activities of the aqueous ethanolic extracts of Gymnema sylvestre (RETZ) R. Br. Ex SCHULT and Sclerocarya birrea (A RICH) HOCHST
Estelle Noëla Hoho YOUL, Sonia Nassouri , Sonia Ilboudo , Moussa Ouédraogo , Charles B. Sombié , Sylvain Ilboudo , Zéphirin P. Dakuyo and Innocent P. Guissou
Gymnema sylvestre (Retz.) R. Br. ex Schult (Asclepiadaceae) and Sclerocarya birrea (A. Rich) Hochst (Anacardiaceae) are two plants used in Burkina Faso in traditional medicine and in the form of phytomedicine in the treatment of diabetes. This study evaluated the effect of aqueous ethanolic extracts of leaves of Gymnema sylvestre and Sclerocar(...)
Gymnema sylvestre, Sclerocarya birrea, oral glucose tolerance test, hypoglycemia, Antihyperglycemia.
ARTICLE
Recent Advances in the Design of Topical Ophthalmic Delivery Systems in the Treatment of Ocular Surface Inflammation and Their Biopharmaceutical Evaluation
Roseline Mazet, Josias B. G. Yaméogo, Denis Wouessidjewe, Luc Choisnard, and Annabelle Gèze
Ocular inflammation is one of the most common symptom of eye disorders and diseases.
The therapeutic management of this inflammation must be rapid and effective in order to avoid
deleterious effects for the eye and the vision. Steroidal (SAID) and non‐steroidal (NSAID) antiinflammatory
drugs and immunosuppressive agents have been shown to b(...)
Mots clés non renseignés
ARTICLE
Characterization of cytotoxic effects of aristolochic acids on the vascular endothelium.
Estelle N. H. YOUL, Cécile Husson, Charaf El Khattabi, Salma El Mere, Anne-Emilie Declèves, Stéphanie Pochet, Joëlle Nortier, Marie-Hélène Antoine
Aristolochic acid nephropathy (AAN) is characterized by interstitial fibrosis, proximal tubular atrophy, and hypoxia. A correlation between a reduced peritubular capillary density and the severity of fibrosis has been demonstrated. As calcium, redox and energetic homeostasis are crucial in maintaining endothelial cell function and survival, we(...)
Aortic ring; Aristolochic acid; Endothelial cells; Intracellular calcium; Oxidative stress.
ARTICLE
Distribution en gros et délivrance des médicaments à base de plantes à travers le circuit pharmaceutique du Burkina Faso
Dori D, Méda N, Gbaguidi F, Quetin-Leclercq J, Semdé R.
Objectif. — Dans le but d’améliorer la contribution des médicaments issus de la pharmacopéetraditionnelle aux soins de santé, des pays africains comme le Burkina Faso ont adopté depuisplusieurs années des politiques et des réglementations organisant leur distribution. Ce travaila pour objectif d’analyser la situation de la vente en gros et au(...)
Médicament à base de plantes; Délivrance; Officine pharmaceutique; Grossiste répartiteur pharmaceutique
ARTICLE
Overview of regulations on medicines derived from traditional Pharmacopoeia in Benin and Burkina Faso
Dori D, Ganfon H, Gbaguidi F, Evrard B, Leclercq JQ, Semdé R
The success of the promotion policies of the Medicines Derived from Traditional Pharmacopoeia (MDTPs) requires a regulation that is adapted to realities and guarantees their quality, efficiency and safeness. This study aims to analyze the legal texts and the current guiding principles obtained from the heads of the departments in charge of tra(...)
WHO, MDTPs, WAEMU, WAHO, Traditional medicine, medicine, regulation, Burkina Faso