Publications (375)
ARTICLE
Co-infection of Toxoplasma gondii with HBV in HIV-infected and uninfected pregnant women in Burkina Faso
D. Ouermi, J. Simpore, A. M. G. Belem, D. S. Sanou, D. S. Karou, D. Ilboudo, C. Bisseye, S. M. Onadja, V. Pietra, S. Pignatelli, C. Gnoula, J. B. Nikiema, G. B. Kabre
Toxoplasma gondii infections can induce serious complications in HIV-infected pregnant women, leading to miscarriage; favour the mother-to-child transmission of HBV and HIV and birth defects. The purposes of this study were: (1) to quantify IgM and IgG antibodies to Toxoplasma gondii in HIV-seropositive and seronegative pregnant women, (2) to(...)
Toxoplasma gondii, co-infection, hépatite B, VIH, grossesse, Burkina Faso, anticorps IgM/IgG, HBsAg, femmes enceintes
ARTICLE
IND-6, a highly divergent IND-type metallo-beta-lactamase from Chryseobacterium indologenes strain 597 isolated in Burkina Faso
Boukaré Zeba, Filomena De Luca, Alain Dubus, Michael Delmarcelle, Jacques Simporé, Odile G. Nacoulma, Gian Maria Rossolini, Jean-Marie Frère, Jean-Denis Docquier
The genus Chryseobacterium and other genera belonging to the family Flavobacteriaceae include organisms that can behave as human pathogens and are known to cause different kinds of infections. Several species of Flavobacteriaceae, including Chryseobacterium indologenes, are naturally resistant to beta-lactam antibiotics (including carbapenems)(...)
Chryseobacterium indologenes, Burkina Faso, IND-6, metallo-beta-lactamase, résistance aux antibiotiques, beta-lactamines, ceftazidime, cefepime, aminoglycosides
ARTICLE
Mother-to-child HIV and HHV-8 transmission in neonates at Saint Camille Medical Centre in Burkina Faso
D. Ilboudo, J. Simpore, D. S. Sanou, D. Karou, D. J. Sia, D. Ouermi, C. Bisseye, T. Sagna, S. Odolini, F. Buelli, V. Pietra, S. Pignatelli, C. Gnoula, J. B. Nikiema, F. Castelli
In Sub-Saharan Africa, many HIV infected people are co-infected with Human Herpes Virus 8 (HHV-8). Therefore, the present study aimed to: (1) identify the pregnant women co-infected by HIV and HHV-8 at Saint Camille Medical Centre; (2) use three molecules (Zidovudine, Nevirapine and Lamivudine) to interrupt the vertical transmission of HIV and(...)
Transmission mère-enfant, VIH, HHV-8, antirétroviraux, PCR, néonatologie, Burkina Faso
ARTICLE
INFANT FEEDING MODALITIES AND MORBIDITY IN HIV INFECTED WOMEN IN RESOURCE-POOR COUNTRIES. A MULTICENTER STUDY IN SUBSAHARAN AFRICA
L. R. Tomasoni, M. Galli, V. Vullo, B. Pedruzzi, V. Pietra, J. Simporé, E. Gianelli, S. Rusconi, A. Riva, Giovanni Guaraldi, K. Luzi, G. Russo, M. Lichtner, G. Carosi, F. Castelli
The optimal feeding modality of infants born to HIV infected mothers in resource-limited settings is still the subject for debate. WHO guidelines recommends exclusive formula feeding wherever it is available, feasible, affordable, safe and sustainable (AFASS). In all other instances, exclusive breastfeeding and early weaning is recommended. Ho(...)
infant feeding, HIV-infected women, resource-poor countries, morbidity, Sub-Saharan Africa, breastfeeding, formula feeding
ARTICLE
HIV NOTIFICATION TO THE PARTNER AMONG PUERPERAS IN SUB-SAHARAN AFRICA
L. R. Tomasoni, M. Galli, V. Vullo, S. Declich, M. Giuliano, V. Pietra, M. Fabiani, J. Simpore, E. Gianelli, S. Rusconi, A. Riva, G. Guaraldi, K. Luzi, G. Russo, M. Lichtner, F. Castelli
HIV serostatus disclosure to sexual partner may lead to clear public health benefits (motivation for partner testing, behavior changes, earlier access to medical care), but it may also lead to women rejection, loss of economic support, physical and emotional abuse. Studies from developing countries suggest that a larger proportion of women com(...)
HIV disclosure, partner notification, puerperas, Sub‑Saharan Africa, public health, stigma, gender dynamics
ARTICLE
Genetic and environmental factors in human osteoporosis from Sub-Saharan to Mediterranean areas
Maria Musumeci, Gianluca Vadalà, Giovanni Tringali, Elio Insirello, Anna Maria Roccazzello, Jacques Simporé, Salvatore Musumeci
The aim of this study was to determine the prevalence of known gene polymorphisms associated with osteoporosis in postmenopausal normal women from Burkina Faso and Sicily, compared to postmenopausal Sicilian women with osteoporosis, and to establish the weight of environmental factors in the mechanism of osteoporosis. Bone mass density (BMD) w(...)
Osteoporosis, Gene polymorphisms, Vitamin D receptor (VDR), Estrogen receptor (ESR), Physical activity, Bone mass density (BMD), Sub-Saharan women, Environmental factors
ARTICLE
Antibiotic resistance in urinary tract bacteria in Ouagadougou
Simplice D. Karou, Idenise P. Ilboudo, Wendyamé M. C. Nadembega, Yaovi Ameyapoh, Djeneba Ouermi, Salvatore Pignatelli, Virginio Pietra, Alfred S. Traoré, Comlan de Souza, Jacques Simporé Demander à ChatGPT
The present study aimed to ascertain for the current situation of antimicrobial resistance of major urinary tract bacteria in Saint Camille Medical Centre. During two consecutive years, 794 urine specimens were analyzed for microorganism isolation and identification. The microorganisms were identified by conventional methods used in the centre(...)
Urinary tract, Antibiotic resistance, Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae
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Outcome and predictive factors of mortality in hospitalized HIV-patients in Burkina Faso
N. Saleri, S. Capone, V. Pietra, G. De Iaco, V. Del Punta, M. Rizzi, M. Levi, S. Rouamba, E. Somé, J. Simporé, A. Patroni, G. Carosi, F. Castelli
Background: The aim of this study was to describe the clinical presentation and predictors of death in a HIV population hospitalized in Ouagadougou, Burkina Faso.
Materials and methods: Baseline demographics, viro-immunological status, clinical presentations, and outcome have been analyzed by univariate analysis and a multivariate model.(...)
HIV, mortality, predictive factors, hospitalized patients, Burkina Faso
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Aetiology of acute gastro-enteritis in children at Saint Camille Medical Centre, Ouagadougou, Burkina Faso
J. Simporé, D. Ouermi, D. Ilboudo, A. Kabre, B. Zeba, V. Pietra, S. Pignatelli, J. B. Nikiema, G. B. Kabre, S. Caligaris, F. Schumacher, F. Castelli
The present study aims at identifying the infectious agents responsible for child Acute GastroEnteritis (AGE) in Ouagadougou. From May 5 2006 to June 22 2008, 648 children aged from 2 to 41 months, with at least an average of 3 loose stools per day have been enrolled for coproculture, parasitology and virology test. Among them, 34 (5.25%) were(...)
Acute gastro-enteritis, Rotavirus, Entero-pathogenic E. coli, Children, Burkina Faso
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Epidemiology of antibiotic resistance in Burkina Faso.
J. Simpore, B. Zeba, D. Karou, D. Ilboudo, S. Pignatelli, O. G. Nacoulma, S. Musumeci
Burkina Faso (West Africa) is a tropical country with a high incidence of infectious diseases. The uncontrolled use of antibiotics against bacterial pathogens has given rise to the emergence of antibiotic resistance in this country. The aims of this study were. (i) to determine the prevalences of the most important pathogenic bacteria, isolate(...)
Antibiotic resistance, Burkina Faso, Escherichia coli, bacterial pathogens, epidemiology
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S100B concentration in colostrums of Burkinabe and Sicilian women
Maria Musumeci, Pasqua Betta, Emanuela Magro, Teresa Isaia, Jacques Simporé, Domenico M. Romeo, Salvatore Musumeci
The aim of this study is to determine the S100B concentration in colostrums of 51 Burkinabe and 30 Sicilian women, still living in their countries, and in case of a difference to search for its explanations, considering also ethnic differences.The concentration of S100B, in colostrums of the first three days from the delivery, was assessed wit(...)
S100B protein, colostrum, Burkinabe women, Sicilian women, lactation, newborns, brain development, ethnicity, immunoluminometric assay, early postnatal adaptation
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Haemoglobin S and haemoglobin C: 'quick but costly' versus 'slow but gratis' genetic adaptations to Plasmodium falciparum malaria
David Modiano, Germana Bancone, Bianca Maria Ciminelli, Fiorenza Pompei, Isa Blot, Jacques Simporé, Guido Modiano
Haemoglobin S (HbS; beta6Glu-->Val) and HbC (beta6Glu-->Lys) strongly protect against clinical Plasmodium falciparum malaria. HbS, which is lethal in homozygosity, has a multi-foci origin and a widespread geographic distribution in sub-Saharan Africa and Asia whereas HbC, which has no obvious CC segregational load, occurs only in a small area(...)
Haemoglobin S, Haemoglobin C, Malaria, Plasmodium falciparum, Genetic adaptation, Burkina Faso, HbS, HbC, Mossi population, Evolutionary genetics
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Sida acuta Burm. f.: a medicinal plant with numerous potencies
SD Karou, WMC Nadembega, DP Ilboudo, D Ouermi, M Gbeassor, C De Souza, J Simpore
Sida acuta is shrub belonging to Malvaceae family. The plant is widely distributed in the subtropical regions where it is found in bushes, in farms and around habitations. Surveys conducted in indigenous places revealed that the plant had many traditional usages that varied from one region to another. The most cited illnesses are fever, headac(...)
Ethnomedicine, medicinal plants, natural substances
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Methylenetetrahydrofolate reductase gene polymorphisms in Burkina Faso: impact on plasma fasting homocysteine and after methionine loading test
Andrea Angius, Jacques Simporé, Ivana Persico, Alessandro Sassu, Dionigio Antonio Prodi, Salvatore Musumeci
In Burkina Faso the levels of plasma homocysteine (Hcy) are lower and the methionine loading tests suggest a more effective Hcy metabolism. The polymorphisms of methylenetetrahydrofolate reductase (MTHFR) showed a relevant difference in the allele frequencies of T MTHFR-677 in young and in old subjects, while the allele frequency of C MTHFR-12(...)
MTHFR gene polymorphism, Homocysteine, Methionine loading test, Burkina Faso, Genetic epidemiology, Plasma biomarkers
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Human Immunodeficiency Virus Type-1 and cytokines in colostrum from HIV-infected mothers in Burkina Faso
Maria Musumeci, Grazia Maria Palano, Piero Castronuovo, Virginio Pietra, Jacques Simpore, Salvatore Musumeci
Background:ThecolostrumofHIV-infectedmotherscontainsahighnumberofHIVcopiesandisconsideredhighlyinfectious.Furthermoreitcontainslargenumbersofmacrophageandothermononuclearcellsthatareknowntoincorporatevirus.WhilepreventionprotocolsinWesterncountriessuggesttheinterruptionofbreastfeeding,atleastforthefirstfewmonthsoflife,thispractice is not advis(...)
HIV, colostrum, Burkina Faso, viral load, cytokines, IL-18, IL-16, IL-12, TGF-beta1, TGF-beta2, mother-to-child transmission (MTCT)