Introduction In the quest for peak performance and public health, the use of plant secondary metabolites to modulate exercise-induced fatigue is gaining traction. This narrative review explores the interaction between phytomolecules (polyphenols, terpenoids, alkaloids), redox homeostasis, and the immune system during physical exertion. Methodology A comprehensive literature search was conducted across international databases (PubMed, ScienceDirect, Google Scholar). The analysis includes biochemical identification methods, in vivo anti-fatigue evaluation models (forced swimming, metabolic biomarkers), and human clinical trials. Results The data reveal that the efficacy of phytomolecules is based on effects that promote recovery, membrane protection, adaptogenic capacity, mental alertness, and glycogen sparing. The study highlights that these compounds increase athletes' tolerance mar...

Introduction: Regional variability in secondary metabolite biosynthesis represents a critical dimension of plant chemodiversity. This study examined Acanthospermum hispidum, Vitex simplicifolia, and Vetiveria nigritana collected from three ecological zones of Burkina Faso (Centre-North, Centre, Cascades), focusing on phytochemical composition and bio activities. Methods: Qualitative profiling of phenolic acids and flavonoids was performed by high-performance thin-layer chromatography (HPTLC). The solvent system consisted of ethyl acetate/formic acid/glacial acetic acid/water (100/11/11/26). The total phenolic content of plant extracts was determined using the Folin–Ciocalteu method. The flavonoid content was determined using the aluminum chloride colorimetric method. The biological potential of the extracts was evaluated using three biological assays: antioxidant activities (ABTS and FR...

Based on asymmetric cryptography, Passkeys Systems are a secure authentication method that can serve as an alternative to traditional authentication methods, such as usernames and passwords. In this paper, we propose a secure approach to enhance private key synchronization mechanisms in passkeys systems. Our secure service is based on Elliptic Curve Diffie-Hellman protocol and Zero-Knowledge Proofs in a peer-to-peer environment. Following a critical analysis of existing works, which highlights recurrent vulnerabilities related to authentication and confidentiality, we introduce a robust architecture using mutual identity verification, secure session key generation and encrypted passkey transfer. The security of our proposed protocol is assessed through a dual approach: an informal analysis based on potential attack modeling, and a formal validation using ProVerif and Scyther tools. The r...

In this work, we prove the existence and regularity of solutions in -norm for some partial functional integrodifferential equations in Banach spaces under the resolvent operator’s theory developed by Grimmer.

Background Traditional medicine in Burkina Faso relies heavily on aromatic plants for the treatment of malaria, bacterial infections, fevers, and related illnesses. Acanthospermum hispidum, Vitex simplicifolia, and Vetiveria nigritana are widely cited species, yet their essential oil composition and biological activities remain underexplored. This study aimed to investigate the ethnobotanical importance, chemical composition, and biological activities (antibacterial and antiplasmodial) of essential oils from these three medicinal plants collected across different ecological regions of Burkina Faso. Methods An ethnobotanical survey was conducted in the Centre-North, Centre, and Cascades regions. Essential oils were extracted by hydrodistillation and analyzed by GC–MS. Antibacterial activity was assessed using MIC and MBC assays, while antiplasmodial activity was evaluated in vitro aga...

Tuberculosis (TB) remains a major public health challenge in Africa, where HIV prevalence varies considerably across countries but remains, overall, higher than the global average. Limited diagnostic capacity and the growing emergence of antimicrobial resistance further contribute to unfavorable treatment outcomes. Bacterial and fungal coinfections may complicate TB diagnosis and treatment, yet evidence from Africa remains fragmented. This systematic review aimed to synthesize available data on the prevalence, microbiological profiles, antimicrobial resistance patterns, and clinical implications of bacterial and fungal coinfections among TB patients in Africa. A systematic review was conducted according to PRISMA 2020 guidelines. PubMed/MEDLINE, ProQuest Central, and African Journals Online were searched for studies reporting bacterial and/or fungal coinfections among TB...

Escherichia coli is a major inhabitant of the intestinal tract of most mammalian species, including humans and animals. This bacterium is classified into four main phylogenetic groups (A, B1, B2, D), with pathogenic strains primarily belong ing to group B2 and, to a lesser extent, group D. This study investigated the correlation between E. coli phylogenetic groups and antibiotic resistance by analyzing 144 strains (95 clinical, 49 food-derived). Species identification was con firmed via uidA gene PCR, and antimicrobial susceptibility was assessed using the Kirby-Bauer disc diffusion method. Extended-spectrum beta-lactamase (ESBL) production was determined through the double synergy test, and phylogenetic classification was performed using triplex PCR. Clinical isolates exhibited high resistance to cephalosporins (up to 56%) and fluoroquinolones (57%), whereas food-derived str...

Roselle (Hibiscus sabdariffa L.), a plant in the Malvaceae family, is of vital importance because its leaves, calyxes and seeds are all consumed. However, this species is still absent from genetic improvement programs in Burkina Faso. The aim of this study was to gain a better understanding of its genetic potential and how this potential is expressed under agro­ecological intensification conditions in a real environment. To do this, six genotypes were tested with cropping practices such as organic fertilization and sowing densities. Qualitative and quantitative traits were measured, as well as the susceptibility of genotypes to attacks by jassids. The results revealed differences in the color, shape and physiological characteristics of the plants. Genotypes differed in growth cycle length, with HSE6 showing a s...

Tea preparation conditions can influence the recovery of bioactive compounds and the antioxidant properties of the resulting beverage. This study compared the effects of heating time and extraction procedure on ten commercial tea samples consumed in Burkina Faso. Each sample underwent two successive decoctions at 100 °C for either 30 min or 1 h and three successive hydro-methanolic macerations. The extracts were examined through qualitative phytochemical screening, quantitative determination of total phenolics, total flavonoids and theophylline, and antioxidant assessment using DPPH, FRAP and SOD assays. Sterols and triterpenes, flavonoid aglycones, tannins and saponins were detected in all extracts. Simida tea showed the highest reported total phenolic content in the decoction extracts (29.42 ± 1.04 mg GAE/100 mg), whereas Moringa tea showed the highest total flavonoid content (5.581 ±...

Program Increment (PI) Planning is a critical synchronization event in scaled Agile methodologies, yet remains largely informal, with limited analytical rigor or strategic alignment. This paper introduces a formal metamodel and a model-driven framework to support structured PI Planning in large-scale software development. Our metamodel captures essential planning artifacts, including features, teams, iterations, risks, and dependencies, and is enriched with OCL constraints for validation and traceability. We extend the model to align planning with business value streams and introduce stakeholder-specific viewpoints for tailored analysis. Compared to tools like Jira or Mural, our approach provides formal semantics, automated reasoning, and extensibility. This work lays the foundation for a Domain-Specific Language (DSL) for PI Planning, bridging the gap between Agile practice and formal m...