Publications (226)
ARTICLE
Acute Oral Toxicity and Vasorelaxant Effects of Hydroethanolic Extract from <i>Lannea microcarpa</i> Engl. & K. Krause (Anacardiaceae) Trunk Barks in Mice Aortas: Possible Involvement of Intracellular Ca<sup> 2+</sup> Mobilization
Mathieu Nitiéma, Bertrand Kafando, Windingoudi Rimwagna Christian Ouédraogo, Bibata Sawadogo, Boukaré Kaboré, Wendkouni Leila Marie Esther Belem-Kabré, Tata Kadiatou Traoré, Jean Claude W. Ouédraogo, Salfo Ouédraogo, Lazare Belemnaba, Aristide Traoré, Moussa Ouédraogo, Noufou Ouédraogo, Bondo Félix Kini, Sylvin Ouédraogo
Lannea microcrapa Engl. & K. Krause (Anacardiaceae) is a fruit and medicinal plant widely used in Burkina Faso. This plant is traditionally used in the treatment of hypertension. The aim of the present study was to evaluate the vasorelaxant effects of the hydroethanolic extract from Lannea microcarpa trunk barks (HE_ELM) on the aorta isolated(...)
Chemistry, Phytochemical, DPPH, EC50, Glibenclamide, Antioxidant, Traditional medicine, Acute toxicity, Pharmacology, Toxicity, Medicine, Biochemistry, Endocrinology, Organic chemistry, In vitro
ARTICLE
Effet antioxydant et capacité quenching de l’oxygène singulet du beurre de karité et de sa fraction phénolique
Bertrand W. F. Goumbri, Olivia Jansen, R.D. Marini, Michel Frédérich, Rasmané Semdé, Touridomon Issa Somé, Sabine Danthine, Ange Mouithys‐Mickalad
Introduction : Les rayons ultraviolet (UVR) peuvent-être nocifs pour la peau, par l’action des radicaux libres générés par les espèces réactives de l’oxygène (ROS), comme l’oxygène singulet (1O2). Le beurre de karité (BK) revendique des propriétés de photoprotection contre les rayons UVA et UVB, par l’action de ses insaponifiables. Notre étude(...)
Chemistry, Molecular biology, Nuclear chemistry, Humanities, Art, Biology
ARTICLE
Analyse comparée de la réglementation des produits cosmétiques des pays de la CEDEAO par rapport aux pays développés
Toé Natacha, Ouoba Kampadilemba, Dori Daniel, Zimé Diawara Hermine, Semdé Rasmané
La persistance des fléaux liés à la mauvaise qualité des produits cosmétiques comme les pathologies dermatologiques et la dépigmentation volontaire, est un problème de santé publique en Afrique de l’Ouest. L’objectif principal de cet article était de décrire les exigences règlementaires relatives aux cosmétiques dans les pays de la CEDEAO, com(...)
Produits cosmétiques, risques sanitaires, CEDEAO, Pays développés
ARTICLE
Evaluation de l'activité de stérilisation des dispositifs médicaux réutilisables au Centre Hospitalier Universitaire Pédiatrique Charles de Gaulle au Burkina Faso
Charles Sombié, Kouka Luc Delma, Moussa Ouédraogo, Rasmané Semdé
La stérilisation des dispositifs médicaux (DM) dans les hôpitaux est primordiale dans la lutte contre les infections associées aux soins. Le butde ce travail était d’évaluer l’activité de stérilisation au Centre Hospitalier Universitaire Pédiatrique Charles de Gaulle (CHUP-CDG). Il s’agissait d’une étude descriptive transversale et prospective(...)
Dispositifs médicaux, Stérilisation, Hôpital
ARTICLE
An innovative one step green supercritical CO2 process for the production of liposomes co-encapsulating both a hydrophobic and a hydrophilic compound for pulmonary administration
Noémie Penoy, Kouka Luc Delma, Hermane Avohou Tonakpon, Bruno Grignard, Brigitte Evrard, Géraldine Piel
Budesonide and salbutamol-loaded liposomes were prepared using an innovative one step supercritical CO2
method without any use of organic solvents. Liposomes composed of soybean phosphatidylcholine, cholesterol
and PEGylated lipid (65/30/5% (m/m)) were produced with a size less than 200 nm, a PdI within the range of
0.3 and 0.35 and encapsu(...)
Liposome, Co-encapsulation, Supercritical carbon dioxide, Green process, Drug delivery, Budesonide, Salbutamol
ARTICLE
study of antiradical activity, phospholipase A and 15-lipoxygenase inhibitory activity of eight malian medicinal plants used by traditional healers to treat inflammatory diseases
ALLO Mahamadou 1,*, Youl Estelle N.H1, Traore Karim2, Diakite A.S Seidina2 , Diakite Mamadou2, Ouedraogo Moussa1, Sanogo Rokia3, Bah Sekou
Pro-inflammatory enzymes play a key role in inflammatory processes and are potential targets of anti-
inflammatory drugs. In this study, the objective was to evaluate the antiradical activity of the extracts and
their ability to inhibit phospholipase A2 and 15-lipoxygenase activity. The hydroethanolic extract of T.
macroptera revealed the s(...)
Phospholipase A2 Ximenia americana Terminalia macroptera Cochlospermum tinctorium Ximenia americana 15-lipoxygenase ABTS Mali.
ARTICLE
Detection of Falsified Antimalarial Sulfadoxine-Pyrimethamine and Dihydroartemisinin-Piperaquine Drugs Using a Low-Cost Handheld Near-Infrared Spectrometer : Hindawi Journal of Analytical Methods in Chemistry Volume 2022
Moussa Yabre, Abdoul Karim Sakira , Moumouni Bande, Bertrand W. F. Goumbri, Sandrine M. Ouattara, Souleymane Fofana, and Touridomon Issa Some
Falsifed drugs are of serious concern to public health worldwide, particularly for developing countries where quality control of
drugs is inefficient. In law enforcement against such fake medicines, there is a need to develop reliable, fast, and inexpensive
screening methods. In this work, the ability of an innovative low-cost handheld near-(...)
falsified- anti-malaria
ARTICLE
Hospital preparations of ethanol‐free furosemide oral solutions: Formulation and stability study
Charles Bavouma Sombié, J. E. Kéré Guetambaba, Hermine Zimé Diawara, Josias Yaméogo, Salfo Ouédraogo, Jonathan Goole, Rasmané Semdé
Furosemide is a diuretic frequently used in the therapeutic management of edema associated with cardiac, renal, and hepatic failure and hypertension. However, there are a very low number of pharmaceutical dosage forms containing furosemide that are suitable for children under 6‐ years old. Therefore, there is a real need to develop hospital pr(...)
Alcohol, edema, furosemide, pediatric patients
ARTICLE
Prise en charge officinale du paludisme simple, l'exemple du Burkina Faso
Coulibaly BNS, Ouoba K, Dori D, Semde R.
Le paludisme est un véritable problème de santé publique. Dans certains pays, les pharmaciens d'officine sont impliqués dans sa prise en charge. Au Burkina Faso, ils réalisent le test de diagnostic rapide et délivrent les antipaludiques. Ces pratiques officinales requièrent un meilleur encadrement réglementaire pour accroître l'accessibilité e(...)
Burkina Faso, cadre législatif, paludisme simple, pratique officinale
ARTICLE
Formulations dermatologiques et évaluation de Lawsonia Inermis linn (lythraceae) sur les brûlures cutanées chez le rat wistar
Hermine Zime-Diawara, Wilfried M. K. Epou, B. G. Josias Yameogo, B. Charles Sombie, Mario Badet, Gervais M. Hounnou, Rasmané Semde
Formulations dermatologiques et évaluation de Lawsonia Inermis linn (lythraceae) sur les brûlures cutanées chez le rat wistar
Lawsonia inermis, brulures, beurre de karité
ARTICLE
Green sweet potato leaves increase Nrf2-mediated antioxidant activity and facilitate benzo[a]pyrene metabolism in the liver by increasing phase II detoxifying enzyme activities in rats
Abel Wend-Soo Zongo, Ray-Yu Yang, Yu-Chen Chen, Meng-Tsan Chiang, Daniel Zogona, Chun-Yin Huang, Hsien-Tsung Yao
Sweet potato leaves (SPL) are a valuable source of phytonutrients with nutritional and various health-promoting benefits. This study evaluated the effects of green and purple SPL supplementation on hepatic xenobiotic-metabolizing enzymes (XME) and membrane transporters, and benzo[a]pyrene (B[a]P) metabolism and B[a]P accumulation in rats. The(...)
Sweet potato, antioxidant, Phase II enzyme
ARTICLE
Audit de l’activité de stérilisation des dispositifs médicaux réutilisables dans le centre hospitalier universitaire pédiatrique Charles de Gaulle au Burkina Faso
Charles Sombié, Kouka Luc Delma, Moussa Ouédraogo, Rasmané Semdé
Introduction : La stérilisation des dispositifs médicaux (DM) dans les hôpitaux est primordiale dans la lutte contre les infections associées aux soins. Le but de ce travail était d’évaluer l’activité de stérilisation dans le Centre hospitalier universitaire pédiatrique Charles de Gaulle (CHUP-CDG). Matériels et méthodes: Il s’agissait d’une é(...)
Political science, Humanities, Philosophy
ARTICLE
Effects of supercritical carbon dioxide under conditions potentially conducive to sterilization on physicochemical characteristics of a liposome formulation containing apigenin
Kouka Luc Delma, Noémie Penoy, Bruno Grignard, Rasmané Semdé, Brigitte Evrard, Géraldine Piel
In this work, the effects of four supercritical carbon dioxide (ScCO2) conditions potentially conductive to sterilization,
on physicochemical characteristics of a liposome formulation containing apigenin (AG) were investigated.
These conditions were: C1 (ScCO2/70 ◦C/150 bar/240 min), C2 (ScCO2/0.25% water/ 0.15% H2O2)/
0.5% acetic anhydride(...)
Supercritical carbon dioxide, Liposomes, Sterilization, Physicochemical Characteristics
ARTICLE
Acute and sub-chronic toxicity study of the mixture of Calotropis procera (Ait). R. Br. (Apocynaceae) and Zanthozylum zanthozyloïdes Lam. (Rutaceae) roots bark powder
Gaëtan Donzéo SOMDA, Noufou Ouédraogo, Gueswindé Geoffroy Ouedraogo, Sylvain Ilboudo, Moussa Ouédraogo, Salfo Ouédraogo, Lamien-Sanou Assita, Bondo Félix Kini, Pierre I. Guissou, Sylvin Ouédraogo
In Burkina Faso, sickle cell syndromes affect 8.42% of hospital patients. For the management of sickle cell anemia, a phytomedicine called FACA® capsules based on a mixture of roots barks powdered from Calotropis procera and Zanthozylum zanthozyloïdes has been developed. The objective of this study was to evaluate the acute and sub-chronic tox(...)
Calotropis procera, Toxicity, Acute toxicity, Apocynaceae, Medicine, Phytomedicine, Chronic toxicity, Median lethal dose, Traditional medicine, Pharmacology, Internal medicine
ARTICLE
Study of antiradical activity, phospholipase A and 15-lipoxygenase inhibitory activity of eight malian medicinal plants used by traditional healers to treat inflammatory diseases
Mahamadou Ballo, Youl Estelle N.H, Traore Karim, Diakite A.S Seidina, M. Diakité, Moussa Ouédraogo, Sanogo Rokia, Sékou Bah
Pro-inflammatory enzymes play a key role in inflammatory processes and are potential targets of anti-inflammatory drugs. In this study, the objective was to evaluate the antiradical activity of the extracts and their ability to inhibit phospholipase A and 15-lipoxygenase activity. The hydroethanolic extract of revealed the strongest reducing p(...)
Arachidonate 5-lipoxygenase, Lipoxygenase, Enzyme, Antioxidant, Chemistry, Phospholipase A2, Inhibitory postsynaptic potential, Traditional medicine, IC50, Anti-inflammatory, Pharmacology, Phospholipase, Biochemistry, Medicine, In vitro, Arachidonic acid