Publications (234)
ARTICLE
Development of a chemical tracer and a chromatographic fingerprint for the quality control of finished products based on hydroethanol extract of fresh leaves of Cassia alata (L.) Roxb (Fabaceae.)
Rodolphe P. F. Yaméogo , Salfo Ouédraogo, Boubacar Yaro, Abdoul Karim Sakira , Bavouma C. Sombié , Josias G. B. Yaméogo , Rasmané Semdé
Cassia alata is used in the treatment of dermatoses. Quality control of herbal products remains difficult and complex. This study aims to develop a quality control approach for a hydroethanol extract of fresh Cassia alata leaves (EHCA), raw material and its antimicrobial soap, the finished product.
The chromatographic fingerprint, phytochemic(...)
Cassia alata; quality control; extract; soap.
COMMUNICATION
Microcapsules of Cimbopogon schoenantus essential oil as antimicrobial preservatives for oral delivery forms
Y. B. Gérard Josias, K. Anne Marie, Z. D. Hermine, S. B. Charles, R. Emilie and S. Rasmané
4ème conférence Européenne des Sciences Pharmaceutiques (4th European Conference on Pharmaceutics)
Mots clés non renseignés
ARTICLE
Physicochemical Quality and In Vitro Bioequivalence of Amoxicillin Capsules Marketed in Burkina Faso, Africa
B. Gérard Josias Yaméogo , Wendpouiré Zoungrana-Somé , B. Charles Sombié , Hermine Zimé-Diawara , Bertrand Goumbri, Aïssata Sanfo-Diasso , Elie Kabré , and Rasmané Semdé
Amoxicillin is a penicillin antibiotic widely prescribed to treat many infections. Several brands of oral forms of amoxicillin are available on the local market. The aim of this study was to evaluate the physicochemical quality and in vitro bioequivalence of several brands of amoxicillin capsules (500 mg) marketed in Burkina Faso. Nine differe(...)
amoxicillin, capsules, physicochemical quality, dissolution
ARTICLE
In vitro inhibition of cyclooxygenases, anti-denaturation and antioxidant activities of Malian medicinal plants
Mahamadou BALLO1,3*, Karim TRAORE2,3, Abdoulaye D.A. GUINDO, Seidina A.S DIAKITE, Blaise DACKOUO, Raogo OUEDRAOGO, Sékou BAH, Mahamadou DIAKITE, Rokia SANOGO and Estelle N. H. YOUL
Cyclooxygenase 2 (COX-2) is involved in the production of prostaglandins that sustain the inflammatory process. Inflammatory cells release a number of reactive species. Furthermore, reactive oxygen species can initiate intracellular signaling cascades and enhance the expression of pro- inflammatory genes. The objective was to study the cycloox(...)
X. americana, T. macroptera, Cyclooxygenase, Antioxidant, Protein denaturation
ARTICLE
Use of supercritical CO2 for the sterilization of liposomes: Study of the influence of sterilization conditions on the chemical and physical stability of phospholipids and liposomes
Kouka Luc Delma, Noémie Penoy, Abdoul Karim Sakira, Sabrina Egrek, Rosalie Sacheli, Bruno Grignard, Marie-Pierre Hayette, Touridomon Issa Somé, Brigitte Evrard, Rasmané Semdé, Géraldine Piel
The effects of four potential supercritical carbon dioxide (ScCO2) sterilization conditions on the chemical stability
of 9 phospholipids and on the physicochemical characteristics of liposomes consisting of stable phospholipids,
as well as their sterilization efficiency were evaluated. These conditions were : C1 (ScCO2/70 ◦C/150
bar/240 min(...)
Phospholipids, Liposomes, Supercritical carbon dioxide, Sterilization, Stability, Sterilizing efficacy
ARTICLE
Développement d’un procédé de production et de stérilisation de liposomes en une seule étape en utilisant le dioxyde de carbone supercritique
Kouka Luc Delma, Noémie Penoy, Abdoul Karim Sakira, Sabrina Egrek, Rosalie Sacheli, Bruno Grignard, Marie‐Pierre Hayette, Touridomon Issa Somé, Brigitte Évrard, Géraldine Piel, Rasmané Semdé
Introduction : les liposomes sont des vecteurs ciblés de médicaments présentant aujourd’hui un grand intérêt pharmaceutique et thérapeutique et généralement administrés par voie parentérale. Cependant, leur fabrication industrielle ainsi que leur stérilisation demeurent un défi. Le dioxyde de carbone supercritique (CO2Sc) constitue aujourd’hui(...)
Humanities, Art, Physics, Philosophy
ARTICLE
Anti-inflammatory Potential of Glycoside Flavonoids from Pterocarpus erinaceus Poir. (Fabaceae) Leaves
Noufou Ouédraogo, Wendkouni Leila Marie Esther Belem-Kabré, Emmanuel A. M. Thiombiano, Tata Kadiatou Traoré, Lazare Belemnaba, Moussa Ouédraogo, Innocent Pierre Guissou
Background: Chronic diseases have become one of the leading causes of death worldwide in recent years. Despite tremendous advances in the treatments of diseases, several concerns remain. Those with inflammatory components are alternatively treated or completed in Burkina Faso with medicinal plants. The present study was designed to identify an(...)
Quercetin, Rutin, Phytochemical, Traditional medicine, DPPH, Glycoside, Chemistry, Kaempferol, Flavonoid, Fabaceae, Antioxidant, Biochemistry, Food science, Botany, Biology, Medicine, Stereochemistry
ARTICLE
Acute Oral Toxicity and Vasorelaxant Effects of Hydroethanolic Extract from <i>Lannea microcarpa</i> Engl. & K. Krause (Anacardiaceae) Trunk Barks in Mice Aortas: Possible Involvement of Intracellular Ca<sup> 2+</sup> Mobilization
Mathieu Nitiéma, Bertrand Kafando, Windingoudi Rimwagna Christian Ouédraogo, Bibata Sawadogo, Boukaré Kaboré, Wendkouni Leila Marie Esther Belem-Kabré, Tata Kadiatou Traoré, Jean Claude W. Ouédraogo, Salfo Ouédraogo, Lazare Belemnaba, Aristide Traoré, Moussa Ouédraogo, Noufou Ouédraogo, Bondo Félix Kini, Sylvin Ouédraogo
Lannea microcrapa Engl. & K. Krause (Anacardiaceae) is a fruit and medicinal plant widely used in Burkina Faso. This plant is traditionally used in the treatment of hypertension. The aim of the present study was to evaluate the vasorelaxant effects of the hydroethanolic extract from Lannea microcarpa trunk barks (HE_ELM) on the aorta isolated(...)
Chemistry, Phytochemical, DPPH, EC50, Glibenclamide, Antioxidant, Traditional medicine, Acute toxicity, Pharmacology, Toxicity, Medicine, Biochemistry, Endocrinology, Organic chemistry, In vitro
ARTICLE
Effet antioxydant et capacité quenching de l’oxygène singulet du beurre de karité et de sa fraction phénolique
Bertrand W. F. Goumbri, Olivia Jansen, R.D. Marini, Michel Frédérich, Rasmané Semdé, Touridomon Issa Somé, Sabine Danthine, Ange Mouithys‐Mickalad
Introduction : Les rayons ultraviolet (UVR) peuvent-être nocifs pour la peau, par l’action des radicaux libres générés par les espèces réactives de l’oxygène (ROS), comme l’oxygène singulet (1O2). Le beurre de karité (BK) revendique des propriétés de photoprotection contre les rayons UVA et UVB, par l’action de ses insaponifiables. Notre étude(...)
Chemistry, Molecular biology, Nuclear chemistry, Humanities, Art, Biology
ARTICLE
Evaluation de l'activité de stérilisation des dispositifs médicaux réutilisables au Centre Hospitalier Universitaire Pédiatrique Charles de Gaulle au Burkina Faso
Charles Sombié, Kouka Luc Delma, Moussa Ouédraogo, Rasmané Semdé
La stérilisation des dispositifs médicaux (DM) dans les hôpitaux est primordiale dans la lutte contre les infections associées aux soins. Le butde ce travail était d’évaluer l’activité de stérilisation au Centre Hospitalier Universitaire Pédiatrique Charles de Gaulle (CHUP-CDG). Il s’agissait d’une étude descriptive transversale et prospective(...)
Dispositifs médicaux, Stérilisation, Hôpital
ARTICLE
Analyse comparée de la réglementation des produits cosmétiques des pays de la CEDEAO par rapport aux pays développés
Toé Natacha, Ouoba Kampadilemba, Dori Daniel, Zimé Diawara Hermine, Semdé Rasmané
La persistance des fléaux liés à la mauvaise qualité des produits cosmétiques comme les pathologies dermatologiques et la dépigmentation volontaire, est un problème de santé publique en Afrique de l’Ouest. L’objectif principal de cet article était de décrire les exigences règlementaires relatives aux cosmétiques dans les pays de la CEDEAO, com(...)
Produits cosmétiques, risques sanitaires, CEDEAO, Pays développés
ARTICLE
An innovative one step green supercritical CO2 process for the production of liposomes co-encapsulating both a hydrophobic and a hydrophilic compound for pulmonary administration
Noémie Penoy, Kouka Luc Delma, Hermane Avohou Tonakpon, Bruno Grignard, Brigitte Evrard, Géraldine Piel
Budesonide and salbutamol-loaded liposomes were prepared using an innovative one step supercritical CO2
method without any use of organic solvents. Liposomes composed of soybean phosphatidylcholine, cholesterol
and PEGylated lipid (65/30/5% (m/m)) were produced with a size less than 200 nm, a PdI within the range of
0.3 and 0.35 and encapsu(...)
Liposome, Co-encapsulation, Supercritical carbon dioxide, Green process, Drug delivery, Budesonide, Salbutamol
ARTICLE
study of antiradical activity, phospholipase A and 15-lipoxygenase inhibitory activity of eight malian medicinal plants used by traditional healers to treat inflammatory diseases
ALLO Mahamadou 1,*, Youl Estelle N.H1, Traore Karim2, Diakite A.S Seidina2 , Diakite Mamadou2, Ouedraogo Moussa1, Sanogo Rokia3, Bah Sekou
Pro-inflammatory enzymes play a key role in inflammatory processes and are potential targets of anti-
inflammatory drugs. In this study, the objective was to evaluate the antiradical activity of the extracts and
their ability to inhibit phospholipase A2 and 15-lipoxygenase activity. The hydroethanolic extract of T.
macroptera revealed the s(...)
Phospholipase A2 Ximenia americana Terminalia macroptera Cochlospermum tinctorium Ximenia americana 15-lipoxygenase ABTS Mali.
ARTICLE
Detection of Falsified Antimalarial Sulfadoxine-Pyrimethamine and Dihydroartemisinin-Piperaquine Drugs Using a Low-Cost Handheld Near-Infrared Spectrometer : Hindawi Journal of Analytical Methods in Chemistry Volume 2022
Moussa Yabre, Abdoul Karim Sakira , Moumouni Bande, Bertrand W. F. Goumbri, Sandrine M. Ouattara, Souleymane Fofana, and Touridomon Issa Some
Falsifed drugs are of serious concern to public health worldwide, particularly for developing countries where quality control of
drugs is inefficient. In law enforcement against such fake medicines, there is a need to develop reliable, fast, and inexpensive
screening methods. In this work, the ability of an innovative low-cost handheld near-(...)
falsified- anti-malaria
ARTICLE
Hospital preparations of ethanol‐free furosemide oral solutions: Formulation and stability study
Charles Bavouma Sombié, J. E. Kéré Guetambaba, Hermine Zimé Diawara, Josias Yaméogo, Salfo Ouédraogo, Jonathan Goole, Rasmané Semdé
Furosemide is a diuretic frequently used in the therapeutic management of edema associated with cardiac, renal, and hepatic failure and hypertension. However, there are a very low number of pharmaceutical dosage forms containing furosemide that are suitable for children under 6‐ years old. Therefore, there is a real need to develop hospital pr(...)
Alcohol, edema, furosemide, pediatric patients