Publications (103)
ARTICLE
Therapeutic effect of aqueous extract from Ampelocissus africana (Lour) Merr rhizomes on testosterone-induced benign prostatic hyperplasia in Wistar rats
Wendkouni Leila Marie Esther Belem-Kabré1* ID , Ollo Da2 ID , Ernest Nogma Sombié1 ID , Raïnatou Boly1 ID , Geoffroy Gueswindé Ouédraogo1 ID , Windingoudi Rimwagna Christian Ouédraogo1,3 ID , Zakaline Yabré1,3 ID , Jean Noel Dado Koussé1,3 ID , Lazare Belemnaba1 ID , Assita Lamien-Sanou4 ID , Noufou Ouédraogo1,3Introduction: Ampelocissus africana is a medicinal plant used to treat several diseases, including those affecting the prostate. This study investigated the effects of the aqueous extract of rhizomes from Ampelocissus africana (AAA) on a testosterone propionate (TP)-induced benign prostatic...
ARTICLE
Phytochemicals properties of Carica papaya Linn seeds’ essential oil and their antifungal and antibacterial activities
OUEDRAOGO Assétou, NIKIEMA Philippe Augustin, YAMEOGO Gérard Josias, SOURABIE Pane Bernadette, BASSAVE Belinda Ramata Hafouo, KONATE Soumaïla, NIKIEMA Marguerite Edith, NIKIEMA Oueogo, GOUMBRI Wendinmi Bertrand Florent and BARRO NicolasCarica papaya seeds have been used as traditional medicine. This study aims to determine the phytochemicals of papaya seeds essential oils their antimicrobial properties. Polyphenolic content and antioxidant properties were determined with standard methods. GC-MS was used to analyze chemical...
ARTICLE
Self-reported health effects of pesticides among cotton farmers from the Central-West region in Burkina Faso
Jean Noël Dado Koussé, Sylvain Ilboudo, Jean Claude Romaric, Pingdwindé Ouédraogo, Moritz Hunsmann , Geoffroy Gueswindé Ouédraogo, Moussa Ouédraogo, Félix Bondo Kini , Sylvin OuédraogoPesticides are chemicals used to control pests with sometime harmful effects on human health. This paper presents results of self-reported health effects experienced by cotton farmers in the Central-West region of Burkina Faso. It was a cross-sectional survey conducted from October to December...
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Phytochemical Screening, Polyphenol and Flavonoid Contents, and Antioxidant and Antimicrobial Activities of Opilia amentacea Roxb. (Opiliaceae) Extracts
Youl O.; Moné-Bassavé B.R.H.; Yougbaré S.; Yaro B.; Traoré T.K.; Boly R.; Yaméogo Josias B Gérard.; Koala M.; Ouedraogo N.; Kabré ElieDermatoses are essentially caused by infection or free radical aggression, immunoallergic
disorders, or can be secondary to general diseases. Management of dermatoses by modern medicine
is complex and costly, and the development of alternative treatments is urgent. Opilia amentacea
Roxb. is a...
COMMUNICATION
Évaluation des attitudes et pratiques sur l’élimination des médicaments non utilisés ou périmés par les ménages de la commune de Ouagadougou
Dori Daniel, Guembre Adama, Meda Nicolas, Semde RasmanéIntroduction
L’ensemble des médicaments qui passe entre les mains des consommateurs n’est pas utilisé et certains arrivent souvent à expiration dans les ménages. Ces produits de santé peuvent être sources de risques accidentels et de pollution lorsqu’ils sont insuffisamment...
COMMUNICATION
Prise en charge des mycoses au Burkina Faso : Etat des lieux de la disponibilité des médicaments antifongiques chez les grossistes répartiteurs
DORI Daniel, TOE Miguel, SAWADOGO Marcel, SANGARE IbrahimIntroduction
Une meilleure prise en charge des mycoses au Burkina Faso est nécessairement liée à une amélioration de la contribution des médicaments antifongiques. Ce travail avait pour objectif, de faire le point de la disponibilité des médicaments antifongiques chez les grossistes...
ARTICLE
Cytochrome P450 2B6 6 distribution among patients living with HIV in Burkina Faso
Raoul KARFO , Fabienne Marie SOUDRE, Alice KIBA, Arnaud KOURAOGO, Elie KABRE, Jean SAKANDEThe function of cytochrome P450 (CYP) enzymes, one of the major catalysts in drug metabolism, is
significantly influenced by genetic polymorphisms leading to substantial inter-individual variability in drug
response and/ or adverse reactions activity. The aim of this study was to determine...
ARTICLE
Phytochemical Analysis and Contractile Effects of Aqueous and Hydroethanolic Extracts of Anastatica hierochuntica L.(Brassicaceae) on the Isolated Uterus of Mice
Belem-Kabré Wendkouni Leila Marie Esther, Nitiéma Mathieu, Odjo Blondine Saïdath, Maman Noura Oumarou, Yaro Boubacar, Kaboré Boukaré, Somda Gaëtan Donzéo, Traoré Tata Kadiatou, Koala Moumouni, Ilboudo Sylvain, Ouédraogo Moussa, Kabré Elie, Ouédraogo NoufouBackground: Anastatica hierochuntica L. (Brassicaceae) has been claimed to treat various conditions, including complicated childbirth. The principal objective of this research was to provide scientific evidence on the contractile effect of the aqueous and hydroethanolic extracts of the whole...
ARTICLE
EVALUATION DES BESOINS EN PREPARATIONS HOSPITALIERES OPHTALMIQUES DANS LES CENTRES HOSPITALIERS UNIVERSITAIRES DU BURKINA FASO
BC Sombié, SP Kambou, H Zimé-Diawara, J Sanou , M Ouédraogo, R SemdéIntroduction : au Burkina Faso, l’absence de médicaments de prédilection dans certaines pathologies oculaires entraine des difficultés dans leur prise en charge thérapeutique. L’objectif de notre travail était d’évaluer les
besoins en préparations hospitalières...
ARTICLE
Evaluation in vitro de l’activité antiproliférative d’une crème à base de beurre de karité et de miel destinée à la prise en charge des plaies cancéreuses
Luc Zongo, Bagora Bayala, Charles Bavouma Sombié , Safiatou Traoré, Jacques Simporé, Rasmané SemdéCertains types de cancer provoquent des plaies cancéreuses (PCs), créant inéluctablement un inconfort pour les malades et leurs soignants ; d’où la nécessité de la recherche de solutions endogènes pour leur traitement dans nos contrées. En effet, le miel, en plus de ses propriétés...
ARTICLE
Assessment of pharmacy professionals’ knowledge and practice on the management and dispensing of investigational drugs in clinical trials
Grissoum Tarnagda, Moussa Ouedraogo, Bavouma Charles Sombié, Luc Kouka Delma , Eric Nagaonle Some, Jean Claude Romaric Pingwendé Ouédraogo, Olivier Sombié , Maxime K. Drabo and Rasmané SemdéIn quality approach for the development of clinical research in Africa, the level of knowledge and practices of professionals influences the quality of the trial, the confidence of the sponsors in the performance of sites. We evaluated the management and dispensing of experimental drugs in...
ARTICLE
Evaluation of the physicochemical quality and antimicrobial performance of amoxicillin and amoxicillin + clavulanic acid discs used in Burkina Faso
Djibril Diallo, B. Gérard Josias Yaméogo, Ouéogo Nikiema, Mohamed Belem, W. Bertrand Goumbri, Belinda Mon´e Bassavé, Abdoul-Salam Ouédraogo, Elie Kabré, Rasmané SemdéAntibiotic discs used in medical analysis laboratories are sourced from multiple manufacturers and suppliers and
must meet stringent quality requirements. This study aimed to assess the quality and performance of amoxicillin
and amoxicillin + clavulanic acid discs used in Burkina Faso. An...
ARTICLE
Subacute Toxicity, Subacute Anti-inflammatory and Anti-arthritic Activities of Combination of Hydroethanolic Extract of Terminalia macroptera and Ximenia americana In-vivo
Mahamadou Ballo, Filkpièrè Léonard Da, Sékou Bah, Rokia Sanogo and Estelle N. H. YoulThe aim of this study was to assess the anti-inflammatory effects of a combination of medicinal plants on two models of inflammation. Subacute toxicity was assessed by daily oral administration of 2000 mg/kg body weight (bw). Subacute inflammation and arthritis were induced using the carrageenan...
COMMUNICATION
Innovations galéniques et prise en charge des maladies infectieuses
YAMEOGO B. Gérard JosiasLes innovations galéniques constituent un élément fondamental du développement pharmaceutique.
Quand on évoque le sujet d’innovation galénique aujourd’hui, on pense à la nanotechnologie, une voie innovante pour véhiculer des molécules thérapeutiques vers une cible. En effet, de...
ARTICLE
Preformulation study for the selection of a suitable polymer for the development of ellagic acid-based solid dispersion using hot-melt extrusion
Isaïe Nyamba, Olivier Jennotte , Charles B. Sombié , Anna Lechanteur , Pierre-Yves Sacre , Abdoulaye Djandé, Rasmané Semdé , Brigitte EvrardEllagic acid is one of the most studied polyphenolic compounds due to its numerous promising therapeutic properties. However, this therapeutic potential remains difficult to exploit owing to its low solubility and low permeability, resulting in low oral bioavailability. In order to allow an...