Publications (103)
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Automédication dans le traitement de l’accès palustre: étude auprès de clients d’officines pharmaceutiques privées de la ville de Ouagadougou, Burkina Faso
L T Ouédraogo, Touridomon Issa Somé, M DiarraI et P GuissouAfin de contribuer à un débat national sur le changement de protocole de traitement du paludisme simple au Burkina Faso, nous avons réalisé une étude transversale descriptive auprès de 397 clients de 45 officines privées de la ville de Ouagadougou.Nous avons noté que la chloroquine (39,...
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Self-medication in the treatment of acute malaria: study based on users of private health drug stores in Ouagadougou, Burkina Faso
L T Ouédraogo, Touridomon Issa Somé, M DiarraI et P GuissouIn order to contribute to the national debate on the change of protocol of the simple forms of malaria treatment in Burkina Faso, we conducted a transversal descriptive study among 397 private pharmacies users in Ouagadougou. The aims of the study were:-making an inventory of the antimalarials...
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Preliminary Clinical Assessment of a Gentamicin-Loaded Monoolein Gel Intended to Treat Chronic Osteomyelitis
Moustapha Ouédraogo, Christophe S. Da, Innocent S. Nacoulma, Hamado Kafando, Rasmané Semdé, Touridomon Issa Some, Rasmata Ouédraogo, Innocent P. Guissou, Jacques Dubois and Karim Amighi,The aim of this study was to perform a preliminary clinical assessment of efficacy and safety of a biodegradable gentamicin-loaded monoolein gel. An open single dose, one treatment study including 19 patients with chronic osteomyelitis caused by a microorganism sensitive to gentamicin was...
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Monoolein–water liquid crystalline gels of gentamicin as bioresorbable implants for the local treatment of chronic osteomyelitis: in vitro characterization
Moustapha Ouédraogo , Rasmané Semdé , Issa Touridomon Somé , Rasmata Traoré/Ouédraogo, , Innocent Pierre Guissou , Viviane Henschel and Jacques DuboisTo maximize the efficacy of chronic osteomyelitis antibiotherapy while reducing antibiotic systemic toxicity, as well as time and costs of hospitalizations, it has been thought that monoolein–water gels incorporating gentamicin sulfate could be used as local, bioresorbable, and...
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Carotenoids Content of Some Locally Consumed Fruits and Yams in Cameroon
Gouado Inocent, Aba Richard Ejoh, Touridomon Issa Some, Florian J Schweigert, Tchouanguep M.FVitamin A deficiency constitutes a public health problem in Cameroon. Data on provitamin A content of fruits locally consumed are scarce. To solve this nutritional problem, it is important to promote the consumption of yellow/orange fruits or green leafy vegetables which are rich sources of...
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Influence of malaria on the serum levels of vitamin A, zinc and calcium of children in Douala-Cameroon
Gouado Inocent, Lehman Leopold Gustave, Some Issa T., Mbouyap Yolande, PankouiMfonkeu Joel Bertand, Ejoh Aba Richard and Tchouanguep Mbiapo FelicitéMalaria is an endemic parasitic disease that prevails particularly in warm tropical regions of the world. Micronutrient malnutrition such as vitamin A and iron deficiencies which is a public health problem in Cameroon is usually highly prevalent in malaria endemic areas. Characterizing the...
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Influence of malaria on the serum levels of vitamin A, zinc and calcium of children in Douala-Cameroon
Gouado Inocent, A. O. Adebiyi, Leopold G Lehman,Touridomon Issa Some, Yolande Mbouyap, Joel Bertand Pankoui Mfonkeu, Aba Richard Ejoh, Felicité Tchouanguep MbiapoMalaria is an endemic parasitic disease that prevails particularly in warm tropical
regions of the world. Micronutrient malnutrition such as vitamin A and iron deficiencies which
is a public health problem in Cameroon is usually highly prevalent in malaria endemic
areas....
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The positive impact of red palm oil in school meals on vitamin A status: study in Burkina Faso
Zeba Augustin, Yves Martin-Prevel, Touridomon Issa Some and Hélène DelisleVitamin A (VA) deficiency is widespread in sub-Saharan Africa and school-age children are a vulnerable group. In Burkina Faso, the production and consumption of red palm oil (RPO) is being promoted as a food supplement for VA. The objective of the study was to assess the impact on serum retinol...
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Validation d'une méthode de dosage des caroténoïdes par CLHP: application à la détermination de teneur en caroténoïdes dans dix variétés de patates douces (Ipo...
Issa T. Somé , Marie-Noël Zagré , Patrick E. Kafando , Mohamed Ag Bendech , Shawn K. Baker , Hélène Deslile , Pierre I. GuissouRésumé La carence en vitamine A (CVA) concerne plus de 250 millions d'enfants âgés de moins de cinq ans dans le monde. Cette carence et ses conséquences sanitaires sont surtout ressenties dans les pays en voie de développement. Trois approches complémentaires sont préconisées pour...
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Prévalence du déficit en Glucose-6-Phosphate Déshydrogénase (G6PD) et de la Drépanocytose chez les nouveau-nés à Ouagadougou (Burkina Faso)
E. Kafando, M. Sawadogo, E. Youl, E. Kabré, E. NacoulmaLe déficit en G6PD et la drépanocytose sont deux pathologies héréditaires du globule rouge responsables d'anémie hémolytiques. ces deux affections souvent associées sont fréquentes dans la population africaine où elles se superposent aux zones d'endémie palustre. l'objectif de notre...
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Stability parameter estimation at ambient temperature from studies at elevated temperatures
Touridomon Issa Some, Philippe Bogaerts, Raymond Hanus, Jacques Dubois and Michel HanocqThe determination of specific kinetic constants ki in pH–profile studies is often undertaken at ambient temperature. However, when dealing with a drug substance that is stable at ambient temperature, the pH–profile study is conducted at a chosen elevated temperature and the kinetic...
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Improved kinetic parameter estimation in pH-profile data treatment
I T Some, P Bogaerts, R Hanus, M Hanocq, J DuboisStatistical problems in temperature stability parameter estimation have been the subject of many papers whereas statistics in, pH-profile parameter estimation have focused little attention. However, the conventional two step method used in data treatment in both cases leads to identical...
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Incorporating batch effects in the estimation of drug stability parameters using an Arrhenius model
I T Some, P Bogaerts, R Hanus, M Hanocq, J DuboisThe nonlinear estimation of drug stability parameters (energy of activation E a and shelf-life t Y) by conventional approaches employs equations relating drug content determination C at time t and temperature T. The identification procedures lead to the determination of only one initial drug...