Malaria is an endemic parasitic disease that prevails particularly in warm tropical regions of the world. Micronutrient malnutrition such as vitamin A and iron deficiencies which is a public health problem in Cameroon is usually highly prevalent in malaria endemic areas. Characterizing the relationship between micronutrient status (vitamin A, zinc and calcium) and malaria infection among children in Douala town (Cameroon), serum levels of zinc, calcium and vitamin A, were assayed in a total of 116 Cameroonian children (62 controls and 54 malaria patients infected by Plasmodium falciparum ) less than six years old by colorimetric and high pressure liquid chromatography (HPLC) techniques respectively showed a significantly lower vitamin A and calcium concentrations (P