Subacute Toxicity, Subacute Anti-inflammatory and Anti-arthritic Activities of Combination of Hydroethanolic Extract of Terminalia macroptera and Ximenia americana In-vivo,
Lien de l'article:
https://dx.doi.org/10.13005/bpj/2688
Auteur(s):
Mahamadou Ballo, Filkpièrè Léonard Da, Sékou Bah, Rokia Sanogo and Estelle N. H. Youl
Auteur(s) tagués:
Estelle Noëla Hoho YOUL ;
Résumé
The aim of this study was to assess the anti-inflammatory effects of a combination of medicinal plants on two models of inflammation. Subacute toxicity was assessed by daily oral administration of 2000 mg/kg body weight (bw). Subacute inflammation and arthritis were induced using the carrageenan air pouch granuloma model and Complete Freund’s Adjuvant (CFA) respectively. After 28 days of administration, the combination at 2000 mg/kg proved to be non-toxic and induced a significant reduction (p
Mots-clés
Terminaliamacroptera Ximenia americana Combination Anti-inflammatory effect Anti-arthritic effects Oxidative stress