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Thromboembolic events in peripartum cardiomyopathy: Results from the ESC EORP PPCM registry,
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Discipline: Médecine clinique
Auteur(s): Jasper Tromp 1 2, Alice M Jackson 3, Magdy Abdelhamid 4, Doaa Fouad 5, Ghada Youssef 6, Mark C Petrie 3, Johann Bauersachs 7, Karen Sliwa 8, Peter van der Meer 9; Investigators of the ESC EORP PPCM Registry
Auteur(s) tagués: YAMEOGO Nobila Valentin
Renseignée par : YAMEOGO Nobila Valentin
Résumé

Peripartum cardiomyopathy (PPCM) is aform of heart failure (HF) that developstowards the end of pregnancy or withinthe first months after delivery.1 Rates ofthromboembolism in PPCM are reportedlyhigher than in many other cardiomyopathies.2In the United States, thromboembolism wasthe most common serious complication inPPCM, occurring in 6.6% of affected women.3In the multinational European Society of Car-diology (ESC) EURObservational ResearchProgramme (EORP) PPCM registry, 5% ofpatients had a thromboembolic event (TE)during the index hospitalization. 4 The peri-partum period is a hypercoagulative phase, anevolutionary remnant to minimize postpar-tum haemorrhage.5 The combination of leftventricular (LV) dilatation, endothelial injury,immobility, and postpartum hypercoagulablestate, may explain the high prevalence of TEin women with PPCM. However, the throm-boembolic risk after discharge remains poorlyunderstood. Therefore, we investigated theclinical characteristics and post-dischargeoutcomes of women hospitalized with PPCM and TE in the prospective observational ESCEORP PPCM registry

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