Pandiaka angustifolia (Vahl) Hepper, a species belonging to Amaranthaceae's family is used in traditional medicine of Burkina Faso for the treatment of several diseases. The aim of this study was to evaluate the phenolics and flavonoids content, the antioxidant capacity, the lipoxygenase and xanthine oxidase inhibition potentials of Pandiaka angustifolia hydroacetonic macerate and fractions. Assay revealed that the Dichloromethane Fraction (DCMF) possess the best inhibitory activity of lipoxygenase, a key enzyme involved in inflammatory process with 83.84±1.89% of inhibition, as regards Xanthine Oxidase (XO) inhibiting percentage, n-hexane fraction (n-HF) exhibited the highest percentage of inhibition with 76.22±4.78% at a concentration of 100µg/ml. Phenolics and flavonoids content in fractions and hydroacetonic macerate evaluation showed that hydroacetonic …

Pandiak angustifolia, antioxidant activity, LOX, XO