Platelets Count During Circulatory Assistance: Involvement in the Changes of Oxygenation Membrane
- Nigerian journal of cardiovascular and thoracic surgery , 6 : 49-49
Résumé
Background: Membrane Oxygenation (MO) complication events during ECMO have decreased in recent decades due to improved coatings and biocompatible materials. The authors studied the evolution of platelet count during Extra-Corporeal Membrane Oxygenation (ECMO) and the causes of MO exchange. Results: Mean age was 56.8±13.4 years. Mean duration of the MO was 5.9±3.1 days, exchanged 26 times (68%) after clot formation. A decrease (p<0.001) in platelet count between the first and second MO exchange was observed in comparison with the baseline. The decrease on day 2 was significant (p<0.001), the delta was 58.000±19.000/µL, followed by a decrease on day 3 (p=0.001). A steady decline was noted after the third MO exchange, afterwards, normalization was observed after ECMO weaning. The average platelet transfusion was 0.6±1.4 units. The more MO was exchanged, the lesser blood products transfusion was done. The overall mortality rate was 39%. Conclusion: The platelets count decreases significantly on day 2 in patients who have being treated with circulatory assistance. Prediction of the need for MO exchange implies circuit checking and the study of hemolysis, coagulation, and hemostasis parameters.
Mots-clés
Platelet, Oxygenation, Circulatory system, Medicine, Cardiology, Internal medicine