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Inflammatory Fibroid Polyp: About Four Observations Including an Appendicular Localization

  • Open journal of pathology , 15 (03) : 126-135
Discipline : Médecine clinique
Auteur(s) :
Renseignée par : IDO Franck Auguste Hermann Adémayali

Résumé

We report four observations of inflammatory fibroid polyps, including a rare
case of appendicular localization. Two of our patients were female and two
were male. They were aged 19, 24, 39, and 4 years, respectively. These were
four cases discovered on surgical specimens after acute digestive episodes requiring
laparotomy. Macroscopically, they were polypoid masses that developed
at the expense of the submucosa. The polyp size ranged from 9 to 4 cm
on the long axis. Microscopically, the masses were composed of spindle and/or
star-shaped cells in a richly vascularized fibromyxoid chorion, reworked by a
polymorphic infiltrate of predsominantly eosinophilic polynuclear cells. Immunohistochemically,
tumor cells expressed high levels of CD34 with a very
low Ki67 proliferation index. Inflammatory adenoid polyp is a rare benign lesion
that can affect all segments of the digestive tract. Its pathogenesis is poorly
understood and remains controversial. Its diagnosis can be difficult, especially
on endoscopic biopsy, leading to its discussion with inflammatory lesions and
certain spindle cell tumors of the digestive tract. It is treated surgically, with a
good prognosis and no recurrence after total excision.

Mots-clés

Intestinal, Inflammatory, Fibroid, Polyp

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