Détails Publication
Antimicrobial resistance and serotype distribution of Streptococcus pneumoniae strains causing childhood infection in Burkina Faso,
Discipline: Sciences sanitaires
Auteur(s): Leonard C. Bere, Jacques Simpore, Simplice D. Karou, Boukaré Zeba, Augustin P. Bere, Elizabeth Bannerman, Jacques Bille, Mireille Dosso
Auteur(s) tagués:
Renseignée par : SIMPORE Jacques
Résumé

In Burkina Faso, a Western African country, reports on pneumococci carriage, resistance patterns and serotypes are inconsistent. The present study was conducted in order to evaluate these parameters. Thus 860 nasopharyngeal swabs were collected from children attending vaccination centers for pneumococci isolation, identification and serotype determination. The susceptibility to 16 antibiotics was assayed as recommended by the National Committee for Clinical Laboratory Standard (NCCLS). The results revealed that the majority of children were of 2 to 24 months age and 73.4% of children were well vaccinated. A carriage rate of 50.6% was recoded among the children. The main serotypes were: 6 (22.22%); 23 (16.67%); 7 and 9 (3.70%); 4, 11, 14, 15, 20 and 24 (1.85%). Serotypesl9, 23, 6, 7 and 18 were linked to penicillin resistance. Globally, high resistance rates to: amikacin, tetracyclin, pefloxacin, cotrimoxazol and penicillins (resistance rates greater than 25%) were recorded; however the following antibiotics remained active on the strains: rifampicin, ceftriaxone, erythromycin, spectinomycin, chloramphenicol, vancomycin, lincomycin and ciprofloxacin.

Mots-clés

Streptococcus pneumoniae, résistance antimicrobienne, sérotypes, enfants, Burkina Faso, antibiotiques

937
Enseignants
8045
Publications
49
Laboratoires
101
Projets