The evolution of 5G New Radio (NR) technology offers unprecedented speeds, ultra-low latency, and the
capability to connect billions of devices. However, these advancements come with significant challenges,
particularly in managing interference during uplink communication. This study presents a comprehensive
investigation into the optimization of 5G NR uplink performance by focusing on two critical channels:
the Physical Uplink Shared Channel (PUSCH) and the Physical Random Access Channel (PRACH). The research explores the impact of intra-cell and inter-cell interference on these channels, highlighting how various User Equipment (UE) and cell configuration parameters influence performance. Key Performance Indicators (KPIs) such as Block Error Rate (BLER) and Correct Detection Rate (CDR) are utilized to assess the effectiveness of proposed interference management strategies. Through rigorous simulations and empirical
evaluations, the study provides valuable insights into optimizing 5G NR networks, aiming to enhance the robustness and reliability of uplink communication in diverse interference scenarios. The findings underscore the importance of adaptive resource allocation and interference mitigation techniques in achieving superior network performance and quality of service (QoS).

5G-NR , Physical Random Access Channel (PRACH), PUSCH, Intra/Inter-Cell Interference, Quality of Service (QoS), Block Error Rate (BLER)