Due to a lack of resources, the diagnosis of Methicillin-resistant Staphylococcus aureus (MRSA) is a challenge in Burkina Faso and West Africa, making MRSA surveillance difficult. In our study, we included 33 beta-lactam resistant S. aureus isolates from the Ouagadougou region which we further tested for susceptibility to cefoxitin using standard methods.Isolates resistant to cefoxitin were further investigated using Chrom MRSA ID® agar medium. In addition, genetic determinants including the mecA gene and SCCmec cassettes were searched using conventional PCR. Fourteen isolates (42.42%) were resistant to cefoxitin, out of which six (18.18%) tested positive when using the Chrom MRSA ID ® agar medium. Six S. aureus isolates (18.18%) tested positive for mecA, and seven (21.21%) tested positive for the SCCmec IVa cassette. This study described circulating MRSA in the city of Ouagadougou. These MRSA harbor mecA resistance genes and SCCmec IVa cassettes.

MRSA ·mecA · SCCmec · Clinical · Hospital effluent · Ouagadougou