Détails Publication
Profile of biochemical markers of malnutrition and iron deficiency in chronic kidney disease patients hemodialyzed at Souro Sanou University Hospital,
Lien de l'article: DOI: 10.5897/AJBR2023.1178
Discipline: Sciences biologiques
Auteur(s): Arnaud Kouraogo, Ollo Da, Fabienne Soudré, Amidou Sawadogo, Alice Kiba, Raoul Karfo, Aoua Semdé, Emmanuel Zongo, Fatou Gueye/Tall, Abdoul Salam Ouédraogo, Sanata Bamba, Georges Anicet Ouédraogo, Elie Kabré and Jean Sakandé
Renseignée par : KARFO W. Raoul
Résumé

Undernutrition and iron deficiency in hemodialysis patients are associated with a high risk of mortality.
The aim of this study was to evaluate the profile of biochemical markers of protein undernutrition and
iron deficiency in hemodialysis patients. This was a descriptive cross-sectional study with data collected
from January 1, 2022 to February 28, 2022. The study included hemodialysis patients who did not present
with an inflammatory syndrome (chronic renal failure [CRP] < 5 mg/L) at the Souro Sanou University
Hospital (SS-UH). The parameters measured in the biochemistry laboratory included CRP, prealbumin,
albumin, alpha-1-glycoprotein, haptoglobin, transferrin, ferritin, serum iron, and transferrin saturation
coefficient (TSC). A total of 41 hemodialysis patients were included in the study, with a mean age of
42.93±12.21 years. The patients were predominantly male, with a sex ratio (M/F) of 1.56. Glomerular
filtration rate was <15 ml/min/1.73 m2 in 85.37% of patients. All biochemical markers were impaired;
however, the major disorders included 2.44% hypoalbuminemia, 2.44% hypoprealbuminemia, 73.17%
hyposideremia, 85% hypotransferrinemia, and a drop in TSC in 39.03% of patients. The incidence of
undernutrition was 4.88%, while iron deficiency was present in 39.03% of patients. The management of
inflammation, undernutrition, and iron deficiency should be integrated into the overall therapeutic
strategy for CKD hemodialysis patients.

Mots-clés

Hemodialysis, malnutrition, iron deficiency, inflammation

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