Salmonella spp and Shigella spp are implicated in gastroenteritis. The increasing antibiotic resistance of these pathogenic bacteria is a public health problem in Burkina Faso. The aim of this study was to investigate the antibiotic susceptibility profile of Salmonella spp and Shigella spp strains isolated from coprocultures at the Centre Hospitalier Universitaire Pédiatrique Charles De Gaulle (CHUPCDG). This was a descriptive cross-sectional study. Data were collected from 1 January 2018 to 30 April 2022 from patients in whom Salmonella spp and Shigella spp strains were identified from coprocultures at the biomedical analysis laboratory. The study population consisted of patients
whose stool culture samples were received and analysed during the study period with complete data. Five thousand four hundred and eighty-seven (5487) coprocultures were performed during the study period, of which 1.6% (87/5487) were positive for Salmonella spp and Shigella spp 45.97% of the patients were aged between 1 and 29 months. Also, 54.02% were male, giving a sex ratio of 1.18 in favour of males. Salmonella spp and Shigella spp were susceptible to ceftriaxone (82.5%), imipenem (70.84%), ciprofloxacin (64.17%), chloramphenicol (63.33%), gentamicin (62.5%) and cefepime (57.5%). This study revealed a wide variety of Salmonella spp and Shigella spp serotypes circulating at the CHUP-CDG. As a result, the most commonly used and affordable antibiotics no longer appear to be effective against these strains.

Salmonella, Shigella, sensitivity, antibiotics, CHUP, CDG