The present study aimed to assess the physico-chemical and microbiological characteristics of leachates produced on the site of Polesgo. Leachate samples have been collected in Polesgo Site (Ouagadougou). Physical and chemical parameters of water samples such as pH, electrical conductivity, Biochemical Oxygen Demand (BOD5), Chemical Oxygen Demand (COD), nitrate, nitrite, fluoride, ammonium, sulfate and ortho-phosphate have been evaluated using standard methods. From experimental results, the basic pH values showed that the leachate is stabilizing and the electrical conductivity gives us information on the dissolved ion content of the effluent water. Concentrations of aluminum, iron and silicon are the most important and can be a source of pollution if infiltration. Low concentrations of lead and chromium were observed and suggest the presence of unauthorized waste in wastes treatment and recovery Center (CTVD). For the microbiological parameters, the high presence of fecal streptococci and E. coli shows the fecal contamination of water in this area.