Fortunately, proper use of available medicinal resources could contribute to greater efficiency within
the health system. This study, using data extracted from the APURMED application, aims to guide the
rational use of drugs in practice within Burkina Faso. Treatments for infectious and non-communicable
diseases represent a significant portion of therapeutic concerns (50.83%, n=860). These concerns
should be addressed to adapt training and professional practices to the context. Mastery of drugs with
potential equivalents (14.15%, n=2579) could enhance drug substitution and identification of therapeutic
redundancies. Drug-related risks stem from either the patient (risk factors, organ insufficiencies, or
vulnerable physiology) or the drug itself (intrinsic risk), as well as unfavorable drug combinations
(hidden risks). Any drug could pose a risk based on the patient profile (such as allergies). More than
half of the drugs (57.21%, n=860) could lead to unfavorable combinations. Prescription analysis is
necessary to identify and mitigate these risks by using relevant clinical and biological data, select the
safest drug or combination, reducing the number of prescribed medications, avoiding therapeutic
redundancies, advising the patient on correct dosage, and monitoring for drug risks.

APURMED, data extraction, rational use of drug, avoidable risk, Burkina Faso