According to the World Health
Organization, multidrug-resistant tuberculosis
(MDR-TB) represents a major obstacle
towards successful TB treatment and
control. In Dakar, MDR-TB management
began in 2010 with the strengthening of
diagnostic resources. The objective of this
study was to identify the factors associated
with multidrug-resistant tuberculosis in
Dakar between 2010 and 2016. We conducted
a case-control study from January 10 to
February 28, 2017 in tuberculosis centers in
Dakar. of 169 cases and 507 controls. We
used logistic regression with Epi-info version
7.2.1. to estimate the odds ratios of
association. Factors significantly associated
with MDR-TB were: residing in a periurban
area (ORa=1.8; 95% CI (1.5-4.9);
p=0.024), presence of MDR-TB in the
entourage of patient (ORa=7.0; 95% CI
(6.1-9.5); p=0.002), previous treatment failure
(ORa=29.5; 95% CI (27.3-30.1);
p=0.000), treatment not directly observed
by a health care provider (ORa=4.3; 95% CI
(4.1-7,2); p=0.000) and irregularity of treatment
(ORa=1.7; 95% CI (0.5-5.4);
p=0.037). Focusing interventions on population
at-risk will prevent MDR-TB.

multidrug-resistant tuberculosis, factors