Periodontal disease in patients with rheumatoid arthritis in Sub-Saharan Africa: A case-control study,
Lien de l'article:
http://dx.doi.org/10.1016/j.jbspin.2016.02.014
Auteur(s):
Dieu-Donné Ouédraogo, Joelle Tiendrébéogoa, Patrice Laurent Wendpouiré Guiguimdé, Pascal Ismaël Nikiéma, Dieudonné Ouédraogo, Fulgence Kaboré; Enselme Zongo, Gilles Hayemd
Auteur(s) tagués:
Wendpouiré Patrice Laurent GUIGUIMDE ;
Dieu-Donné OUEDRAOGO ;
Résumé
Rheumatoid arthritis (RA) and periodontal disease are both
common in humans throughout the world. Clinical and epidemiological data support a link between these two conditions . Periodontal disease has been implicated in the initiation and perpetuation of autoimmunity in RA via activation of the enzyme peptidyl arginine deiminase 4 (PAD4) produced by bacteria such as Porphyromonas gingivalis . The objective of this work was to assess the prevalence of periodontal disease and to identify associated factors in black African patients with RA.
Mots-clés
rheumatoid arthritis periodontal disease anti-citrullinated peptide antibodies