Evaluation of enzymes inhibition activities of medicinal plant from Burkina Faso.,
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Auteur(s): Bangou M. J., M. Kiendrebeogo, M. Compaoré, A. Y. Coulibaly, N. T. R. Meda, B. Zeba, N. A. Abarca, J. Millogo-Rasolodimby and O. G. Nacoulma
Auteur(s) tagués: Moussa COMPAORE ;
Résumé

The aim of the present study was to evaluate some enzymes inhibitory effects of 11 plant species belonging to 9 families from Burkina Faso. Methanolic extracts were used for their Glutathione-s-transferase (GST), Acetylcholinesterase (AChE), Carboxylesterase (CES) and Xanthine Oxidase (XO) inhibitory activities at final concentration of 100| rg mL_1. The total phenolics, flavonoids and tannins were also determined spectrophotometrically using Folin-Ciocalteu, A1C13 and ammonium citrate iron reagents, respectively. Among the 11 species tested, the best inhibitory percentages were found with Euphorbia hirta, Sclerocarya birrea and Scoparia dulcis (inhibition 40%) followed by Annona senegalensis, Annona squamosa, Polygala arenaria and Ceratotheca sesamoides (inhibition 25%). The best total phenolic and tannin contents were found with S. birrea with 56.10 mg GAE/100 mg extract …

Mots-clés

Polyphenolic compounds glutathion-S-transferase Acetylcholinesterase Carboxylesterase

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