Serum Amylase Activity in Children Living with HIV-1 at the Charles de Gaulle Pediatric University Hospital in Ouagadougou,
Auteur(s): Fabienne Marie Soudre, Arnaud Kouraogo, Abdou Nombre, Issa Tonde, Ollo Da, Thierry Etienne Kafando, Asciel Laël Ouedraogo, Delwende Job Tenkodogo, Alice Kiba, Raoul Karfo, Elie Kabre, Jean Sakande
Résumé

Biological monitoring is an essential part of the management of HIV infection. The aim of this study was to assess serum
amylase activity during follow-up of children living with HIV-1 (CLHIV-1) at the Charles de Gaulle Pediatric University
Hospital (CHUP-CDG). This was a descriptive and analytical cross-sectional study, with retrospective data collection from
January 1, 2020 to December 31, 2022. Patients under 15 years of age who were being monitored for HIV-1 at CHUP-CDG
and who had undergone a serum amylase assay during the study period were included. A total of 746 patients have been
included, with a M/F sex ratio of 0.91 and a mean age of 8.52±4.08 years. Among CLHIV-1, 88.05% had a TCD4 lymphocyte
count 500/mm3 and 60.32% an undetectable plasma viral load (PVL). The incidence of hyperamylasemia in the study
population was 57.64%. Hyperamylasemia was significantly more frequent in children aged 0-2 years (p

Mots-clés

Hyperamylasemia Serum Amylase Activity Children HIV-1 Burkina Faso

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