Retinoblastoma: The Situation in Burkina Faso over Ten Years,
Auteur(s): Amadou Ouattara 1, Anicet Corneille Beremwidougou2 , Paté Sankara3, Mariam Traore/Dolo4 , Tierinyê Armand Meda 5, Windinmanégdé Pierre Djiguimde6, Rolande Kabore7, Chantal Gabrielle Bouda 7, Gertrude Augustine Meda/Hien7 , Jerome Sanou 7, Jean Wenceslas Diallo4, Ahgbatouhabeba Zabsonre/Ahnoux7
Résumé

Abstract
Context: In Burkina Faso, there is only one retinoblastoma treatment center located in the capital. Nowadays, the treatment of retinoblastoma has benefited from the contribution of scientific progress. Objective: The aim was to
take stock of the situation of retinoblastoma in the pediatric oncology department from January 1, 2010 to December 31, 2019. Materials and Methods: This was a descriptive cross-sectional study with retrospective data collection over a 10-year period, based on records of patients admitted to pediatric oncology department of CHU-YO. Data were analysed using CS Pro version 7.2 software. Categorical variables were compared using Pearson’s Chi-square test at the 5% significance level. Overall survival was estimated using the Kaplan-Meier method. Operational definitions were used for lost to follow-up, consultation and diagnosis delays. Results: We collected a total of 204 cases in 10 years, i.e. an annual average of 20.4 cases/year. The mean age at diagnosis was 37.5 months for unilateral cases and 26.4 months for bilateral cases. Male predominance was noted, with a sex ratio of 1.31. The majority of patients came from disadvantaged backgrounds (72% farming fathers and 91% housewives). Clinically, leukocoria and exophthalmos were the main presenting features. The average time to consultation was long (8.73 months) and unilateral localization was predominantly unilateral at 77%. In terms of treatment, 102 patients were eligible for curative treatment and 80 for pallia- tive treatment. The prognosis was poor, with 41% death and numerous cases
Keywords
Retinoblastoma, Prognosis, Pediatric Oncology, CHU-YO, Burkina Faso

Mots-clés

Keywords Retinoblastoma Prognosis Pediatric Oncology CHU-YO

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