Mathematical analysis and optimal control of dengue fever epidemic model,
Auteur(s): YODA Yacouba, OUEDRAOGO Harouna , OUEDRAOGO Dramane and GUIRO Aboudramane
Auteur(s) tagués: Harouna OUEDRAOGO ;
Résumé

In this article, we are working on an SEIR-SI type model for dengue disease in order to
better observe the dynamics of infection in human beings. We calculate the basic
reproduction number R0 and determine the equilibrium points. We then show the
existence of global stability in each of the different states depending on the value of
R0. Moreover, to support the theoretical work, we present numerical simulations
obtained using Python. We also study the sensitivity of the parameters included in
the expression of R0 with the aim of identifying the most influential parameters in
the dynamics of dengue disease spread. Finally, we introduce two functions u and v,
respectively indicating the treatment of the infected people and any prevention
system minimizing contact between humans and the disease causing vectors. We
present the curves of the controlled system after calculating the optimal pair of
controls capable of reducing the dynamics of the disease spread, still using Python.

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