Publications (228)
ARTICLE
Effects of Crude Shea Butters and Their Polar Extracts on Singlet Oxygen Quenching and Against Rose Bengal-Induced HaCaT Cell Phototoxicity
Bertrand W. F. Goumbri , Olivia Jansen , Roland Marini Djang’eing’a , Michel Frederich , Rasmané Semdé , Touridomon Issa Somé , Sabine Danthine and Ange Mouithys-Mickalad ,*
Abstract: Shea butter (SB) is a raw material fat obtained from Vitellaria paradoxa C.F. Gaertn kernels. We investigated the direct and indirect protective effects of 10 traditional
and industrial SBs and their polar extracts on cell-free systems using ABTS and DPPH radical scavenging assays as well as on singlet oxygen (1O2) produced by Rose(...)
shea butter; phenol; antioxidant; singlet oxygen; photoprotection; HaCaT
ARTICLE
Gestion des risques toxicologiques au Burkina Faso : contribution du Laboratoire national de santé publique
Naâ-Imwine Stanislas Dimitri Meda , Cheick Armand Noukami Palm, Moumouni Bandé, Arouna Zoungrana , Odile Gambo, Soumaïla Konaté, Abdou Azize W. Ouédraogo, Pane Bernadette Sourabié-Ouattara, Fulbert Nikiema, Elie Kabré, Moussa Ouédraogo
vec l’augmentation des produits chimiques dans le monde, l’homme et son environnement sont de plus en plus exposés à leurs effets toxiques. Ainsi, une veille toxicologique est mise en place à tous les niveaux, afin de renseigner sur les risques chimiques éventuels et orienter sur la mise en œuvre d’interventions de santé publique pour y remédi(...)
Risque toxicologique ; Expertise toxicologique ; Réquisition judiciaire ; LNSP
ARTICLE
In Silico Inhibitory Potential of Isolated Molecules of Scoparia dulcis L. (Scrophulariaceae) on SARS-CoV-2 Main Protease Mpro
Ouedraogo, M. , Ouedraogo, W. , Yameogo, H. , Traore, I. , Boly, R. , Ouedraogo, N. , Semde, R. and Ouedraogo, S.
Background: The Coronavirus disease 2019 (COVID-19) pandemic, caused by the SARS-CoV-2 coronavirus, remains a global threat despite lifting the health emergency. Scientists from all continents have been mobilized to develop vaccines and medicines for prevention and cure. In Burkina Faso, traditional healers proposed using Scoparia dulcis L., a(...)
COVID-19, Molecular Docking, Mpro, Biomolecules, Scoparia dulcis
ARTICLE
In Silico Inhibitory Potential of Isolated Molecules of Scoparia dulcis L. (Scrophulariaceae) on SARS-CoV-2 Main Protease Mpro
Moussa Ouedraogo, Windbedema Prisca Ouedraogo, Hermann W. Yameogo, Inna T. Traore, Raïnatou Boly, Noufou Ouedraogo, Rasmané Semde, Sylvin Ouedraogo
Background: The Coronavirus disease 2019 (COVID-19) pandemic, caused
by the SARS-CoV-2 coronavirus, remains a global threat despite lifting the
health emergency. Scientists from all continents have been mobilized to develop
vaccines and medicines for prevention and cure. In Burkina Faso, traditional
healers proposed using Scoparia dulcis L(...)
COVID-19, Molecular Docking, Mpro, Biomolecules, Scoparia dulcis
ARTICLE
Characterization of medication errors in the Neonatology Unit of Teaching Pediatric Hospital of Ouagadougou, Burkina Faso
Moussa Ouedraogo, Guembre Adama, Emile W. Ouedraogo, Geoffroy W. Dibri, Charles B. Sombie, Aïssata Kabore and Kisito Nagalo
Medication errors were reported for the first time in 1962. Neonates are more exposed than other pediatric and adult patients. In Burkina Faso, a few medication errors in neonate care units are known.
This study aimed to characterize medication errors along the clinical medication circuit in the neonatology unit of the teaching pediatric hosp(...)
Medication errors, newborns, error characterization, Burkina Faso
ARTICLE
Medication Reconciliation at the Admission of the Medical Emergency Unit of Teaching Pediatric Hospital of Ouagadougou, Burkina Faso
Ouédraogo, M., Dibri, G.W., Ouédraogo, E.W., Ouoba, K., Adama, G., Sombie, C.B., Ouédraogo, A., Yoni, H., Kabore, A. and Youl, E.N.H.
Abstract
Introduction and Problem Statement: Many medication errors occur during
the community and hospital transition. Indeed, the World Health Organization
launched the international “High 5S” project to implement medication
reconciliation in healthcare facilities to reduce them and ensure patients a safe,
high-quality healthcare pathwa(...)
Admission Medication Reconciliation, Medication-Error, Medical Emergency Unit, Pediatric, Burkina Faso
ARTICLE
Contribution of clinical pharmacy to the rational and safe use of medicines in the neonatology unit of the pediatric university hospital Charles de Gaulle of Ouagadougou, Burkina Faso
Moussa Ouedraogo, Bonsdawindé Pagbelguem, Arsène Wendwaoga Nikiema, Charles B. Sombié, Emile W. Ouedraogo, Colette Zoungrana, Kisito Nagalo, Aïssata Kabore
Background: Newborns are exposed to drug therapeutic risks due to off-label prescribing and immaturity. The purpose of this study is to identify drug-related problems through the prescription and administration of drugs in the neonatology Unit and identify the need for pharmaceutical interventions.
Methods: To assess drug-related problems, a(...)
Neonatology, Drug-related problem, Medicines prescription and administration, Burkina Faso
ARTICLE
Comparison of good review practices of seven countries participating in the ECOWAS medicines regulatory harmonisation initiative: identifying opportunities for improvement
Owusu-Asante M, Darko DM, Seaneke S, Nacoulma A, Traore OIO, Adeyeye CM, Akinyemi A, Assane C, Clamoungou CÉKM, Ndao OK, Kande RN, Komeh J, Mansaray S, Lamboni D, Agba M, Walker S and Salek S
Introduction: When implemented by national and regional regulatory agencies
good review practices (GRevPs) support the timely high-quality review of
medicines for enhanced patients’ availability to safe, quality and efficacious
innovative and generic products. It is important that all aspects of GRevPs are
continuously evaluated and update(...)
Economic Community of West African States Medicines Regulatory Harmonisation (ECOWAS-MRH), good review practices, African Medicines Agency (AMA), regulatory reliance, Optimising Efficiencies in Regulatory Agencies (OpERA)
ARTICLE
Impacts of SAYE PLUS , an Antimalarial Phytomedicine With Potential Anti‐COVID‐19, on the Physical, Biological, and Genotoxicity Parameters of Rodents in Short‐Term Toxicity Studies
Joël Ouédraogo, Sylvain Ilboudo, Geoffroy Gueswindé Ouédraogo, Virginie Dakuyo, Salfo OUEDRAOGO, Gaëtan Donzéo SOMDA, Jean Claude Romaric Pingdwindé Ouédraogo, Moussa Ouédraogo, Rasmané Semdé, Sylvin Ouédraogo
In response to the COVID-19 pandemic and following the World Health Organization's call for action, several traditional medicine recipes were used without any scientific prerequisites concerning their safety. The current study investigated several short-term toxicity parameters of SAYE PLUS, an antimalarial phytomedicine used in COVID-19 patie(...)
Phytomedicine, Toxicity, Medicine, No-observed-adverse-effect level, Acute toxicity, Pharmacology, Genotoxicity, Physiology, Median lethal dose, Toxicology, Traditional medicine, Internal medicine, Biology
ARTICLE
Optimization and Standardization of the Extraction Method of Balanites aegyptiaca Del. Seeds (Zygophyllaceae) Used in the Formulation of an Antiparasitic Phytomedicine
Mohamed Bonewendé Belemlilga, Salfo Ouedraogo, Gilchrist Abdoul Laurent Boly, Do Harouna Dao, Jonas Tiami Coulibaly, Jean Claude Romaric Pingdwindé Ouedraogo, Souleymane Compaoré, Sidiki Traore, Moumouni Koala, Estelle Noëla Hoho Youl, Lazare Belemnaba, Félix Bondo Kini, Aristide Traore, Séni Kouanda and Sylvin Ouedraogo
Background/Objectives: Balanites aegyptiaca Del. (Zygophyllaceae) is widely used in traditional medicine, both human and veterinary, throughout Africa for its many properties, including antiparasitic properties. This experimental study aims to optimize the extraction conditions of the seeds of Balanites aegyptiaca Del. Methods: Aqueous macerat(...)
optimization; standardization; Balanites aegyptiaca; antiparasitic phytomedicine
ARTICLE
Guidelines for rational use of drug based data extracted from the APURMED application in Burkina Faso
Tinguéri L. B., Ki A. , Nikiema S., Kafando H. , Bationo B. G., Coulibaly M.1 , Zan I., Rouamba M. , Zoungrana A. B. , Semdé S., Zohoncon T. M., Somé P. C., Bonkoungou V. and Ouédraogo M.
Fortunately, proper use of available medicinal resources could contribute to greater efficiency within
the health system. This study, using data extracted from the APURMED application, aims to guide the
rational use of drugs in practice within Burkina Faso. Treatments for infectious and non-communicable
diseases represent a significant p(...)
APURMED, data extraction, rational use of drug, avoidable risk, Burkina Faso
ARTICLE
Investigation on chemical composition and insecticidal activity against Anopheles gambiae of essential oil obtained by co-distillation of Cymbopogon citratus and Hyptis suaveolens from Western Burkina Faso
Bily Nebié, Constantin M. Dabiré, Remy K. Bationo, Dieudonné D. Soma, Moussa Namountougou, Siaka Sosso, Roger C. H. Nebié, Roch K. Dabiré, Eloi Palé and Pierre Duez
Background Essential oils of Cymbopogon citratus and Hyptis suaveolens are known for their insecticidal propertiesbut remain ineffective against mosquitoes resistant to synthetic insecticides. In order to improve insecticidal properties of these plants, this study aimed to investigate the chemical composition and insecticidal activity against A(...)
Cymbopogon citratus, Hyptis suaveolens, Co-distillation, Essential oil, Insecticidal activity, Resistant Anopheles gambiae
ARTICLE
Evaluation of acute and subacute toxicity and sedative effect of Feretia apodanthera Delile (Rubiaceae) leaves
Gniènèfèrètien Nounaféri Awa Silué, Sylvain Ilboudo, Lenoir Thierry Ayoman Djadji, Geoffroy Ouedraogo, Mohamed Bonewendé Belemlilga, Gisèle Kouakou-Siransy, Rasmané Semdé
Evaluation of acute and subacute toxicity and sedative effect of Feretia apodanthera Delile (Rubiaceae) leaves)
Feretia apodanthera Delile, toxicity, sedative effects
ARTICLE
Development of a digital application for the rational use of medicine in Burkina Faso
Tinguéri L. B.1 , Ki A.2 , Nikiema S.1 , Kafando H.1 , Bationo B. G.3 , Coulibaly M.1 , Zan I.4 , Rouamba M.5 , Zoungrana A. B.1 , Semdé S.1 , Zohoncon T. M. 6,7, Somé P. C.1 , Bonkoungou V. 8 and Ouédraogo M.9
Developing countries lack enough human and financial resources, making it difficult for them to
respond adequately to the population's essential health needs. Using digital applications to promote
the rational use of medicines presents a solution to increase the health system's efficiency and
encourage saving limited medicinal resources.(...)
Digital application, rational use of medicines, drug database, equivalence search option, prescription analysis options.
ARTICLE
PROTECTIVE EFFECT OF COMBINATION OF ETHANOLIC EXTRACTS OF XIMENIA AMERICANA AND TERMINALIA MACROPTERA AGAINST ALCOHOL-INDUCED HEPATOTOXICITY IN RATS
Mahamadou Ballo, Sekou Bah, Estelle NH Youl
Objective: The aim of this study was to evaluate the hepatoprotective effect of the combination
Methods: Serum liver markers, tissue antioxidant activity, and histological changes in the livers of rats from the blank, negative (distilled water), positive (silymarin 100 mg/kg bw), and test (combination 500 mg/kg bw) groups were measured after(...)
Antioxidant, Hepatoprotective, Ximenia americana, Terminalia macroptera, Combination$